Histamine diphosphate monohydrate - ≥99% , Histamine H1 receptor agonist, CAS No.51-74-1, Histamine H1 receptor agonist

CAS: 51-74-1 Cat. No.: H106192 Molecular Weight: 325.15 Beilstein Registry Number: 3744619 EC Number: 200-118-4

GRADE & PURITY ≥99%

Synonyms

Histamine phosphate [USP] | MFCD00064316 | Histamine Phosphate,(S) | Histamine acid phosphate | AC-24100 | DTXSID7058759 | HY-A0129 | Histamine diphosphate, 98% | Histaminephosphate | QWB37T4WZZ | Histamine phosphate (USP) | UNII-QWB37T4WZZ | 1H-Imidazole

Storage

Store at -20°C,Argon charged

Shipped In

Ice chest + Ice pads

Overview

Histamine bisphosphate monohydrate is a potent agonist of histamine receptors.
A potent histamine receptor agonist

Specifications

Synonyms

Histamine phosphate [USP] | MFCD00064316 | Histamine Phosphate, (S) | Histamine acid phosphate | AC-24100 | DTXSID7058759 | HY-A0129 | Histamine diphosphate, 98% | Histaminephosphate | QWB37T4WZZ | Histamine phosphate (USP) | UNII-QWB37T4WZZ | 1H-Imidazole

Specifications & Purity

≥99%

Biochemical and Physiological Mechanisms

Phosphate salt of Histamine . Acts as a neurotransmitter in the nervous system and as a local mediator in the gut, skin, and immune system.

Storage

Store at -20°C, Argon charged

Shipped In

Ice chest + Ice pads

This product requires cold chain shipping. Ground and other economy services are not available.

Action Type

AGONIST

Mechanism of action

Histamine H1 receptor agonist

Note

Wherever possible, you should prepare and use solutions on the same day. However, if you need to make up stock solutions in advance, we recommend that you store the solution as aliquots in tightly sealed vials at -20°C. Generally, these will be useable for up to one month. Before use, and prior to opening the vial we recommend that you allow your product to equilibrate to room temperature for at least 1 hour. Need more advice on solubility, usage and handling? Please visit our frequently asked questions (FAQ) page for more details.

Purity

≥99%

Names and Identifiers

• Pubchem Sid: 504753988
• Pubchem Sid Url: https://pubchem.ncbi.nlm.nih.gov/substance/504753988
• Canonical Smiles: C1=C(NC=N1)CCN.OP(=O)(O)O.OP(=O)(O)O
• IUPAC Name: 2-(1H-imidazol-5-yl)ethanamine;phosphoric acid
• InChIKey: ZHIBQGJKHVBLJJ-UHFFFAOYSA-N
• INCHI: 1S/C5H9N3.2H3O4P/c6-2-1-5-3-7-4-8-5;2*1-5(2,3)4/h3-4H,1-2,6H2,(H,7,8);2*(H3,1,2,3,4)
• Isomeric SMILES: C1=C(NC=N1)CCN.OP(=O)(O)O.OP(=O)(O)O
• WGK Germany: 3
• RTECS: NI5425000
• Alternate CAS: 23297-93-0
• Molecular Weight: 325.15
• Beilstein: 3744619
• Reaxy-Rn: 6250304
• Reaxys-RN_link_address: https://www.reaxys.com/reaxys/secured/hopinto.do?context=S&query=IDE.XRN=6250304&ln=

Taxonomic Classification

Taxonomy Tree

• Kingdom Organic compounds
  • Superclass Organic nitrogen compounds
    • Class Organonitrogen compounds
      • Subclass Amines
        • Level5 Primary amines
          • Level6 2-arylethylamines

• Kingdom: Organic compounds
• Superclass: Organic nitrogen compounds
• Class: Organonitrogen compounds
• Subclass: Amines
• Intermediate Tree Nodes: Primary amines
• Direct Parent: 2-arylethylamines
• Alternative Parents: Aralkylamines Organic phosphoric acids and derivatives Imidazoles Heteroaromatic compounds Azacyclic compounds Organopnictogen compounds Organic oxides Monoalkylamines Hydrocarbon derivatives
• Molecular Framework: Aromatic heteromonocyclic compounds
• Substituents: 2-arylethylamine - Aralkylamine - Organic phosphoric acid derivative - Heteroaromatic compound - Imidazole - Azole - Azacycle - Organoheterocyclic compound - Organic oxygen compound - Organopnictogen compound - Organic oxide - Hydrocarbon derivative - Primary aliphatic amine - Aromatic heteromonocyclic compound
• Description: This compound belongs to the class of organic compounds known as 2-arylethylamines. These are primary amines that have the general formula RCCNH2, where R is an organic group.
• External Descriptors: phosphate salt

Data sources

1. Djoumbou Feunang Y, Eisner R, Knox C, Chepelev L, Hastings J, Owen G, Fahy E, Steinbeck C, Subramanian S, Bolton E, Greiner R, and Wishart DS. ClassyFire: Automated Chemical Classification With A Comprehensive, Computable Taxonomy. Journal of Cheminformatics, 2016, 8:61.

DOI: 10.1186/s13321-016-0174-y

Mechanisms of Action

Chemical and Physical Properties

• Solubility: Soluble in water.
• Sensitivity: Heat & Moisture sensitive
• Melt Point(°C): 126-132°C
• Molecular Weight: 307.140 g/mol
• Hydrogen Bond Donor Count: 8
• Hydrogen Bond Acceptor Count: 10
• Rotatable Bond Count: 2
• Exact Mass: 307.033 Da
• Monoisotopic Mass: 307.033 Da
• Topological Polar Surface Area: 210.000 Ų
• Heavy Atom Count: 18
• Formal Charge: 0
• Complexity: 114.000
• Isotope Atom Count: 0
• Defined Atom Stereocenter Count: 0
• Undefined Atom Stereocenter Count: 0
• Defined Bond Stereocenter Count: 0
• Undefined Bond Stereocenter Count: 0
• The total count of all stereochemical bonds: 0
• Covalently-Bonded Unit Count: 3

XLogP3