Iopamidol - 10mM in DMSO , Diagnostic agent, CAS No.60166-93-0, Diagnostic agent

CAS: 60166-93-0 Cat. No.: I424998 Molecular Weight: 777.09 EC Number: 262-093-6

GRADE & PURITY 10mM in DMSO

Synonyms

iopamidol|60166-93-0|Iopamiron|Isovue|Iopamiro|Niopam|Solutrast|iomapidol|Gastromiro|Iopamidol 300|Iopamidolum|Oypalomin|Iopamiron 300|Iopamiron 370|Jopamiron 200|Iopamiro 370|Isovue-370|Niopam 300|Iopamidol-200|Iopamidol-250|Iopamidol-300|Iopamidol-370|S

Storage

Store at -80°C

Shipped In

Dry ice packs + Cold packs

Overview

Iopamidol is a nonionic radiocontrast medium. It is used as a diagnostic aid (radiopaque medium).

Specifications

Synonyms

iopamidol | 60166-93-0 | Iopamiron | Isovue | Iopamiro | Niopam | Solutrast | iomapidol | Gastromiro | Iopamidol 300 | Iopamidolum | Oypalomin | Iopamiron 300 | Iopamiron 370 | Jopamiron 200 | Iopamiro 370 | Isovue-370 | Niopam 300 | Iopamidol-200 | Iopamidol-250 | Iopamidol-300 | Iopamidol-370 | S

Specifications & Purity

10mM in DMSO

Storage

Store at -80°C

Shipped In

Dry ice packs + Cold packs

This product requires cold chain shipping. Ground and other economy services are not available.

Mechanism of action

Diagnostic agent

Product Properties

• ALogP: -2.4

Names and Identifiers

• Canonical Smiles: CC(C(=O)NC1=C(C(=C(C(=C1I)C(=O)NC(CO)CO)I)C(=O)NC(CO)CO)I)O
• IUPAC Name: 1-N,3-N-bis(1,3-dihydroxypropan-2-yl)-5-[[(2S)-2-hydroxypropanoyl]amino]-2,4,6-triiodobenzene-1,3-dicarboxamide
• InChIKey: XQZXYNRDCRIARQ-LURJTMIESA-N
• INCHI: 1S/C17H22I3N3O8/c1-6(28)15(29)23-14-12(19)9(16(30)21-7(2-24)3-25)11(18)10(13(14)20)17(31)22-8(4-26)5-27/h6-8,24-28H,2-5H2,1H3,(H,21,30)(H,22,31)(H,23,29)/t6-/m0/s1
• Isomeric SMILES: C[C@@H](C(=O)NC1=C(C(=C(C(=C1I)C(=O)NC(CO)CO)I)C(=O)NC(CO)CO)I)O
• Molecular Weight: 777.09
• Reaxy-Rn: 6773333
• Reaxys-RN_link_address: https://www.reaxys.com/reaxys/secured/hopinto.do?context=S&query=IDE.XRN=6773333&ln=

Taxonomic Classification

Taxonomy Tree

• Kingdom Organic compounds
  • Superclass Benzenoids
    • Class Benzene and substituted derivatives
      • Subclass Halobenzenes

• Kingdom: Organic compounds
• Superclass: Benzenoids
• Class: Benzene and substituted derivatives
• Subclass: Halobenzenes
• Intermediate Tree Nodes: Not available
• Direct Parent: Iodobenzenes
• Alternative Parents: Aryl iodides Secondary alcohols Propargyl-type 1,3-dipolar organic compounds Carboximidic acids Primary alcohols Organopnictogen compounds Organonitrogen compounds Organoiodides Hydrocarbon derivatives
• Molecular Framework: Aromatic homomonocyclic compounds
• Substituents: Iodobenzene - Aryl halide - Aryl iodide - Secondary alcohol - Carboximidic acid - Carboximidic acid derivative - Propargyl-type 1,3-dipolar organic compound - Organic 1,3-dipolar compound - Organooxygen compound - Organonitrogen compound - Organoiodide - Organohalogen compound - Organopnictogen compound - Alcohol - Primary alcohol - Hydrocarbon derivative - Organic nitrogen compound - Organic oxygen compound - Aromatic homomonocyclic compound
• Description: This compound belongs to the class of organic compounds known as iodobenzenes. These are aromatic compounds containing one or more iodine atoms attached to a benzene.
• External Descriptors: organoiodine compound - benzenedicarboxamide - pentol

Data sources

1. Djoumbou Feunang Y, Eisner R, Knox C, Chepelev L, Hastings J, Owen G, Fahy E, Steinbeck C, Subramanian S, Bolton E, Greiner R, and Wishart DS. ClassyFire: Automated Chemical Classification With A Comprehensive, Computable Taxonomy. Journal of Cheminformatics, 2016, 8:61.

DOI: 10.1186/s13321-016-0174-y

Associated Targets(Human)

CYP2D6 Tclin Cytochrome P450 2D6 (33882 Activities)

Discover Target: CYP2D6

Activity Type	Relation	Activity value	Units	Action Type	Journal	PubMed Id	doi	Assay Aladdin ID

CYP1A2 Tchem Cytochrome P450 1A2 (26471 Activities)

Discover Target: CYP1A2

Activity Type	Relation	Activity value	Units	Action Type	Journal	PubMed Id	doi	Assay Aladdin ID

CYP2C9 Tchem Cytochrome P450 2C9 (32119 Activities)

Discover Target: CYP2C9

Activity Type	Relation	Activity value	Units	Action Type	Journal	PubMed Id	doi	Assay Aladdin ID

CYP2C19 Tchem Cytochrome P450 2C19 (29246 Activities)

Discover Target: CYP2C19

Activity Type	Relation	Activity value	Units	Action Type	Journal	PubMed Id	doi	Assay Aladdin ID

CYP3A4 Tclin Cytochrome P450 3A4 (53859 Activities)

Discover Target: CYP3A4

Activity Type	Relation	Activity value	Units	Action Type	Journal	PubMed Id	doi	Assay Aladdin ID

LMNA Tbio Prelamin-A/C (36751 Activities)

Discover Target: LMNA

Activity Type	Relation	Activity value	Units	Action Type	Journal	PubMed Id	doi	Assay Aladdin ID

PMP22 Tbio Peripheral myelin protein 22 (699 Activities)

Discover Target: PMP22

Activity Type	Relation	Activity value	Units	Action Type	Journal	PubMed Id	doi	Assay Aladdin ID

USP1 Tchem Ubiquitin carboxyl-terminal hydrolase 1 (22556 Activities)

Discover Target: USP1

Activity Type	Relation	Activity value	Units	Action Type	Journal	PubMed Id	doi	Assay Aladdin ID

Associated Targets(non-human)

Hdac6 Histone deacetylase 6 (222 Activities)

Discover Target: Hdac6

Activity Type	Relation	Activity value	Units	Action Type	Journal	PubMed Id	doi	Assay Aladdin ID

Plasmodium falciparum (966862 Activities)

Explore this target

Activity Type	Relation	Activity value	Units	Action Type	Journal	PubMed Id	doi	Assay Aladdin ID

rep Replicase polyprotein 1ab (378 Activities)

Discover Target: rep

Activity Type	Relation	Activity value	Units	Action Type	Journal	PubMed Id	doi	Assay Aladdin ID

Mechanisms of Action

Chemical and Physical Properties

• Melt Point(°C): >320° C (dec.)
• Molecular Weight: 777.100 g/mol
• XLogP3: -2.400
• Hydrogen Bond Donor Count: 8
• Hydrogen Bond Acceptor Count: 8
• Rotatable Bond Count: 10
• Exact Mass: 776.854 Da
• Monoisotopic Mass: 776.854 Da
• Topological Polar Surface Area: 188.000 Ų
• Heavy Atom Count: 31
• Formal Charge: 0
• Complexity: 583.000
• Isotope Atom Count: 0
• Defined Atom Stereocenter Count: 1
• Undefined Atom Stereocenter Count: 0
• Defined Bond Stereocenter Count: 0
• Undefined Bond Stereocenter Count: 0
• The total count of all stereochemical bonds: 0
• Covalently-Bonded Unit Count: 1

References

1. Yurong Gu, Zi Song, Zijun Dong, Feiyun Sun, Chengchun Jiang, Jikun Qi.  (2022)  Efficient degradation and deiodination of iopamidol by UV/sulfite process: Assessment of typical process parameters and transformation paths.  ENVIRONMENT INTERNATIONAL,      [PMID:35952467] [10.1016/j.envint.2022.107383]

2. Jingdong Yang, Yu Li, Zequn Yang, Kaimin Shih, Guang-Guo Ying, Yong Feng.  (2022)  Activation of ozone by peroxymonosulfate for selective degradation of 1,4-dioxane: Limited water matrices effects.  JOURNAL OF HAZARDOUS MATERIALS,      [PMID:35739743] [10.1016/j.jhazmat.2022.129223]

3. Shuwei Xiao, Pengchao Wang, Jian Zhao, Zhengyun Ling, Ziyan An, Zhouyang Fu, Weijun Fu, Xu Zhang.  (2021)  Bi-layer silk fibroin skeleton and bladder acellular matrix hydrogel encapsulating adipose-derived stem cells for bladder reconstruction.  Biomaterials Science,  9  (18): (6169-6182).  [PMID:34346416] [10.1039/D1BM00761K]

4. Chaoqun Tan, Yuhao Guo, Wangqi Yu, Ming Chen, Lianghu Su, Dongsheng Wang.  (2025)  Alkaline regeneration of activated carbon in biological activated carbon filter from drinking water treatment：Adsorption of micropollutant.  Journal of Environmental Chemical Engineering,      [PMID:] [10.1016/j.jece.2025.118035]

5. Qiang Tan, Zhonglin Chen, Jimin Shen, Pengwei Yan, Jing Kang, Binyuan Wang, Shengxin Zhao, Yang Shen, Yabin Li.  (2025)  In situ construction of ZnFe-layered double oxides on biochar for improving interfacial adsorption-catalysis of ozone achieves efficient water purification.  SEPARATION AND PURIFICATION TECHNOLOGY,      [PMID:] [10.1016/j.seppur.2025.135358]