L-Glutamic acid γ-(7-amido-4-methylcoumarin) trifluoroacetic acid - ≥98% , CAS No.72669-53-5

CAS: 72669-53-5 Cat. No.: L334056 Molecular Weight: 304.30(free base basis)

GRADE & PURITY ≥98%

Synonyms

G-L-Glutamic acid 7-amido-4-methylcoumarin | H-GLU(AMC)-OH | FD21475 | gamma-l-glutamic acid 7-amido-4-methylcoumarin | AS-49086 | AKOS026674350 | (S)-2-amino-5-(4-methyl-2-oxo-2H-chromen-7-ylamino)-5-oxopentanoic acid | SCHEMBL57489 | (S)-2-Amino-5-((4-m

Storage

Store at -20°C

Shipped In

Ice chest + Ice pads

Overview

L-Glutamic acid γ-(7-amido-4-methylcoumarin) is a substrate for aminopeptidase or the assay of γ-glutamyl transferase producing a blue fluorescent solution upon cleavage.

Specifications

Synonyms

G-L-Glutamic acid 7-amido-4-methylcoumarin | H-GLU(AMC)-OH | FD21475 | gamma-l-glutamic acid 7-amido-4-methylcoumarin | AS-49086 | AKOS026674350 | (S)-2-amino-5-(4-methyl-2-oxo-2H-chromen-7-ylamino)-5-oxopentanoic acid | SCHEMBL57489 | (S)-2-Amino-5-((4-m

Specifications & Purity

≥98%

Storage

Store at -20°C

Shipped In

Ice chest + Ice pads

This product requires cold chain shipping. Ground and other economy services are not available.

Purity

≥98%

Names and Identifiers

• Pubchem Sid: 488191120
• Canonical Smiles: CC1=CC(=O)OC2=C1C=CC(=C2)NC(=O)CCC(C(=O)O)N
• IUPAC Name: (2S)-2-amino-5-[(4-methyl-2-oxochromen-7-yl)amino]-5-oxopentanoic acid
• InChIKey: JPOAPPISZAGCAO-NSHDSACASA-N
• INCHI: 1S/C15H16N2O5/c1-8-6-14(19)22-12-7-9(2-3-10(8)12)17-13(18)5-4-11(16)15(20)21/h2-3,6-7,11H,4-5,16H2,1H3,(H,17,18)(H,20,21)/t11-/m0/s1
• Isomeric SMILES: CC1=CC(=O)OC2=C1C=CC(=C2)NC(=O)CC[C@@H](C(=O)O)N
• WGK Germany: 3
• Molecular Weight: 304.30(free base basis)
• Reaxy-Rn: 49596745
• Reaxys-RN_link_address: https://www.reaxys.com/reaxys/secured/hopinto.do?context=S&query=IDE.XRN=49596745&ln=

Taxonomic Classification

Taxonomy Tree

• Kingdom Organic compounds
  • Superclass Organic acids and derivatives
    • Class Carboxylic acids and derivatives
      • Subclass Amino acids, peptides, and analogues
        • Level5 Amino acids and derivatives
          • Level6 Alpha amino acids and derivatives
            • Level7 Glutamine and derivatives

• Kingdom: Organic compounds
• Superclass: Organic acids and derivatives
• Class: Carboxylic acids and derivatives
• Subclass: Amino acids, peptides, and analogues
• Intermediate Tree Nodes: Amino acids and derivatives - Alpha amino acids and derivatives
• Direct Parent: Glutamine and derivatives
• Alternative Parents: Coumarins and derivatives 1-benzopyrans L-alpha-amino acids N-arylamides Pyranones and derivatives Fatty amides Benzenoids Heteroaromatic compounds Secondary carboxylic acid amides Lactones Amino acids Monocarboxylic acids and derivatives Oxacyclic compounds Carboxylic acids Organic oxides Monoalkylamines Hydrocarbon derivatives Carbonyl compounds Organopnictogen compounds
• Molecular Framework: Aromatic heteropolycyclic compounds
• Substituents: Glutamine or derivatives - Coumarin - Alpha-amino acid - Benzopyran - 1-benzopyran - L-alpha-amino acid - N-arylamide - Pyranone - Fatty amide - Pyran - Benzenoid - Fatty acyl - Heteroaromatic compound - Amino acid - Secondary carboxylic acid amide - Carboxamide group - Lactone - Oxacycle - Organoheterocyclic compound - Carboxylic acid - Monocarboxylic acid or derivatives - Hydrocarbon derivative - Organonitrogen compound - Primary aliphatic amine - Organooxygen compound - Organic nitrogen compound - Organopnictogen compound - Primary amine - Organic oxide - Carbonyl group - Amine - Organic oxygen compound - Aromatic heteropolycyclic compound
• Description: This compound belongs to the class of organic compounds known as glutamine and derivatives. These are compounds containing glutamine or a derivative thereof resulting from reaction of glutamine at the amino group or the carboxy group, or from the replacement of any hydrogen of glycine by a heteroatom.
• External Descriptors: Not available

Data sources

1. Djoumbou Feunang Y, Eisner R, Knox C, Chepelev L, Hastings J, Owen G, Fahy E, Steinbeck C, Subramanian S, Bolton E, Greiner R, and Wishart DS. ClassyFire: Automated Chemical Classification With A Comprehensive, Computable Taxonomy. Journal of Cheminformatics, 2016, 8:61.

DOI: 10.1186/s13321-016-0174-y

Chemical and Physical Properties

• Solubility: Soluble in water (partly), and formic acid (20 mg/ml).
• Refractive Index: n20D1.64 (Predicted)
• Specific Rotation[α]: α20/D +33°±2°, c = 1, 50% in AcOH; α20/D +10.5°±1°, 589 nm, c = 0.3 in 1N NaOH
• Boil Point(°C): ~624.9° C at 760 mmHg (Predicted)
• Melt Point(°C): 190-196° C (dec.)
• Molecular Weight: 304.300 g/mol
• XLogP3: -1.900
• Hydrogen Bond Donor Count: 3
• Hydrogen Bond Acceptor Count: 6
• Rotatable Bond Count: 5
• Exact Mass: 304.106 Da
• Monoisotopic Mass: 304.106 Da
• Topological Polar Surface Area: 119.000 Ų
• Heavy Atom Count: 22
• Formal Charge: 0
• Complexity: 502.000
• Isotope Atom Count: 0
• Defined Atom Stereocenter Count: 1
• Undefined Atom Stereocenter Count: 0
• Defined Bond Stereocenter Count: 0
• Undefined Bond Stereocenter Count: 0
• The total count of all stereochemical bonds: 0
• Covalently-Bonded Unit Count: 1