LCS-1 - Moligand™, 10 mM in DMSO , CAS No.41931-13-9

CAS: 41931-13-9 Cat. No.: L1494909 Molecular Weight: 255.1

GRADE & PURITY Moligand™, 10 mM in DMSO

Storage

Store at -80°C

Shipped In

Dry ice packs + Cold packs

Overview

LCS-1 is a superoxide dismutase 1 ( SOD1 ) inhibitor. LCS-1 inhibits SOD1 activity with an IC 50 value of 1.07 μM. LCS-1 induces the early- and late-stage apoptosis of multiple myeloma (MM.1S) cells.

Specifications

Specifications & Purity

Moligand™, 10 mM in DMSO

Storage

Store at -80°C

Shipped In

Dry ice packs + Cold packs

This product requires cold chain shipping. Ground and other economy services are not available.

Grade

Moligand™

Names and Identifiers

• Isomeric SMILES: CC1=CC(=CC=C1)N2C(=O)C(=C(C=N2)Cl)Cl
• UN Number: 2811
• Packing Group: III
• Molecular Weight: 255.1
• Reaxy-Rn: 790931
• Reaxys-RN_link_address: https://www.reaxys.com/reaxys/secured/hopinto.do?context=S&query=IDE.XRN=790931&ln=

Chemical and Physical Properties

• Refractive Index: n20D1.63 (Predicted)
• Boil Point(°C): ~339.6° C at 760 mmHg (Predicted)
• Melt Point(°C): 117° C

References

1. Renzheng Zhang, Xian Guo, Chunnian Liang, Jie Pei, Pengjia Bao, Mancai Yin, Fude Wu, Min Chu, Ping Yan.  (2022)  Identification and Validation of Yak (Bos grunniens) Frozen–Thawed Sperm Proteins Associated with Capacitation and the Acrosome Reaction.  JOURNAL OF PROTEOME RESEARCH,      [PMID:36251486] [10.1021/acs.jproteome.2c00528]