Lefamulin acetate (Xenleta) - 10mM in DMSO , Bacterial 70S ribosome inhibitor, CAS No.1350636-82-6, Bacterial 70S ribosome inhibitor

CAS: 1350636-82-6 Cat. No.: L421318 Molecular Weight: 567.78 EC Number: 695-920-8 PubChem CID: 86346053
AVAILABLE TO ORDER
GRADE & PURITY 10mM in DMSO
Synonyms
BC-3781 acetateAcetic acid | 2-​[[(1R,​2R,​4R)​-​4-​amino-​2-​hydroxycyclohexyl]​thio]​-​,(3aS,​4R,​5S,​6S,​8R,​9R,​9aR,​10R)​-​6-​ethenyldecahydro-​5-​hydroxy-​4,​6,​9,​10-​tetramethyl-​1-​oxo-​3a,​9-​propano-​3aH-​cyclopentacycloocten​-​8-​yl ester acet
Storage
Store at -80°C
Shipped In
Dry ice packs + Cold packs
 ·  off list, applied to all prices below.
Size
Status
Price
Qty
1ml
L421318-1ml
1

$47.90

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Why this grade

10mM in DMSO for sensitive chromatographic and analytical workflows requiring minimal baseline interference.

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Storage & shipping

Store at -80°C Ships Dry ice packs + Cold packs Check lot-specific COA for exact specifications.

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Quality documents

SDS, COA, datasheet, and spec sheet available for download. Lot-specific COA accessible via lot number lookup.

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Literature proof

Cited in 0 peer-reviewed publications across chromatography, organic synthesis, and cross-coupling reactions.

Overview

Information

Lefamulin acetate (Xenleta) Lefamulin acetate (Xenleta, BC-3781 acetate) is a pleuromutilin antibiotic for community-acquired bacterial pneumonia (CABP) treatment. Lefamulin acetate inhibits protein synthesis by binding to the peptidyl transferase center of the 50S bacterial ribosome , thus preventing the binding of transfer RNA for peptide transfer.

Specifications

Synonyms
BC-3781 acetateAcetic acid | 2-​[[(1R, ​2R, ​4R)​-​4-​amino-​2-​hydroxycyclohexyl]​thio]​-​, (3aS, ​4R, ​5S, ​6S, ​8R, ​9R, ​9aR, ​10R)​-​6-​ethenyldecahydro-​5-​hydroxy-​4, ​6, ​9, ​10-​tetramethyl-​1-​oxo-​3a, ​9-​propano-​3aH-​cyclopentacycloocten​-​8-​yl ester acet
Specifications & Purity
10mM in DMSO
Biochemical and Physiological Mechanisms
Lefamulin acetate (Xenleta, BC-3781 acetate) is a pleuromutilin antibiotic for community-acquired bacterial pneumonia (CABP) treatment. Lefamulin acetate inhibits protein synthesis by binding to the peptidyl transferase center of the 50S bacterial ribosom
Storage
Store at -80°C
Shipped In
Dry ice packs + Cold packs
This product requires cold chain shipping. Ground and other economy services are not available.
Action Type
INHIBITOR
Mechanism of action
Bacterial 70S ribosome inhibitor
Product Properties
ALogP0.083
HBD Count3
Rotatable Bond6
Names and Identifiers
Isomeric SMILES C[C@@H]1CC[C@@]23CCC(=O)[C@H]2[C@@]1([C@@H](C[C@@]([C@H]([C@@H]3C)O)(C)C=C)OC(=O)CS[C@@H]4CC[C@H](C[C@H]4O)N)C.CC(=O)O
PubChem CID 86346053
Molecular Weight 567.78

Documentation

📋 Safety Data Sheet (SDS)

Comprehensive hazard, handling, storage, and regulatory compliance document.

Download SDS →

✅ Certificate of Analysis (COA)

Lot-specific quality data. Enter your lot number to retrieve the exact COA.

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📊 Datasheet

Quick-reference summary of product specifications and applications.

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🔬 Specification Sheet

Full quality attributes and acceptance criteria for this grade.

View spec sheet →

Advanced Data

Certificates(CoA,COO,BSE/TSE and Analysis Chart)
C of A & Other Certificates(BSE/TSE, COO):
Analytical Chart:
Chemical and Physical Properties
DMSO(mg / mL) Max Solubility100
DMSO(mM) Max Solubility176.124555285498
Water(mg / mL) Max Solubility100
Water(mM) Max Solubility176.124555285498
Solution Calculators
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