Histamine H1 receptor (HRH1)

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  1. Lofepramine, Inhibitor of NET;Inhibitor of SERT
    CAS: 23047-25-8 EC Number: 245-396-8 Formula: C26H27ClN2O Molecular Weight: 418.97
    Moligand™ ? Moligand™ — Aladdin's line of ligands and bioactive small molecules. Use for receptor, pathway, and binding studies needing defined small-molecule tools. ≥97%
    In Stock Item #: L287104
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    IUPAC Name
    1-(4-chlorophenyl)-2-[3-(5,6-dihydrobenzo[b][1]benzazepin-11-yl)propyl-methylamino]ethanone
    SMILES
    CN(CCCN1C2=CC=CC=C2CCC3=CC=CC=C31)CC(=O)C4=CC=C(C=C4)Cl
    InChIKey
    SAPNXPWPAUFAJU-UHFFFAOYSA-N
    InChI
    1S/C26H27ClN2O/c1-28(19-26(30)22-13-15-23(27)16-14-22)17-6-18-29-24-9-4-2-7-20(24)11-12-21-8-3-5-10-25(21)29/h2-5,7-10,13-16H,6,11-12,17-19H2,1H3
    Synonyms
    1-(4-chlorophenyl)-2-{[3-(10,11-dihydro-5H-dibenzo[b,f]azepin-5-yl)propyl]methylamino}ethanone | Gamanil | HMS3413F21...
  2. Zotepine, Antagonist of 5-HT 1A receptor;Antagonist of 5-HT 1B receptor;Antagonist of 5-HT 1D receptor;Antagonist of 5-ht 1e receptor;Antagonist of 5-HT 2A receptor;Antagonist of 5-HT 2C receptor;Antagonist of 5-HT 6 receptor;Antagonist of 5-HT 7 receptor;Antagonis
    CAS: 26615-21-4 EC Number: 662-775-7 PubChem CID: 5736 Formula: C18H18ClNOS Molecular Weight: 331.86
    Moligand™ ? Moligand™ — Aladdin's line of ligands and bioactive small molecules. Use for receptor, pathway, and binding studies needing defined small-molecule tools. ≥98%(HPLC)
    In Stock Item #: Z132909
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    IUPAC Name
    2-(3-chlorobenzo[b][1]benzothiepin-5-yl)oxy-N,N-dimethylethanamine
    SMILES
    CN(C)CCOC1=CC2=CC=CC=C2SC3=C1C=C(C=C3)Cl
    InChIKey
    HDOZVRUNCMBHFH-UHFFFAOYSA-N
    InChI
    1S/C18H18ClNOS/c1-20(2)9-10-21-16-11-13-5-3-4-6-17(13)22-18-8-7-14(19)12-15(16)18/h3-8,11-12H,9-10H2,1-2H3
    Synonyms
    NCGC00182081-02 | NCGC00182081-03 | 2-(8-chlorobenzo[b][1]benzothiepin-6-yl)oxy-N,N-dimethylethanamine | Q226905 | 2-...
  3. Levocetirizine dihydrochloride, Histamine H1 receptor antagonist
    CAS: 130018-87-0 EC Number: 641-093-3 PubChem CID: 9955977 Formula: C21H25ClN2O3·2HCl Molecular Weight: 461.81
    Solid Moligand™ ? Moligand™ — Aladdin's line of ligands and bioactive small molecules. Use for receptor, pathway, and binding studies needing defined small-molecule tools. ≥98%
    In Stock Item #: L124802
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    IUPAC Name
    2-[2-[4-[(R)-(4-chlorophenyl)-phenylmethyl]piperazin-1-yl]ethoxy]acetic acid;dihydrochloride
    SMILES
    C1CN(CCN1CCOCC(=O)O)C(C2=CC=CC=C2)C3=CC=C(C=C3)Cl.Cl.Cl
    InChIKey
    PGLIUCLTXOYQMV-GHVWMZMZSA-N
    InChI
    1S/C21H25ClN2O3.2ClH/c22-19-8-6-18(7-9-19)21(17-4-2-1-3-5-17)24-12-10-23(11-13-24)14-15-27-16-20(25)26;;/h1-9,21H,10-16H2,(H,25,26);2*1H/t21-;;/m1../sshow more
    Synonyms
    (R)-2-(2-(4-((4-Chlorophenyl)(phenyl)methyl)piperazin-1-yl)ethoxy)acetic acid dihydrochloride | good sense levocetiri...
  4. GSK-239512, Histamine H3 receptor antagonist
    CAS: 720691-69-0 EC Number: 629-871-0 Formula: C23H27N3O2 Molecular Weight: 377.48
    Solid Moligand™ ? Moligand™ — Aladdin's line of ligands and bioactive small molecules. Use for receptor, pathway, and binding studies needing defined small-molecule tools. ≥98%
    Out of Stock Item #: G177277
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    IUPAC Name
    1-[6-[(3-cyclobutyl-1,2,4,5-tetrahydro-3-benzazepin-7-yl)oxy]pyridin-3-yl]pyrrolidin-2-one
    SMILES
    C1CC(C1)N2CCC3=C(CC2)C=C(C=C3)OC4=NC=C(C=C4)N5CCCC5=O
    InChIKey
    YFRBKEVUUCQYOW-UHFFFAOYSA-N
    InChI
    1S/C23H27N3O2/c27-23-5-2-12-26(23)20-7-9-22(24-16-20)28-21-8-6-17-10-13-25(19-3-1-4-19)14-11-18(17)15-21/h6-9,15-16,19H,1-5,10-14H2
    Synonyms
    4I7U5C459M | 1-(6-((3-CYCLOBUTYL-2,3,4,5-TETRAHYDRO-1H-BENZO[D]AZEPIN-7-YL)OXY)PYRIDIN-3-YL)PYRROLIDIN-2-ONE | 2-Pyrr...
  5. Piperacetazine
    CAS: 3819-00-9 EC Number: 223-312-0 PubChem CID: 19675 Formula: C24H30N2O2S Molecular Weight: 410.57
    Solid Moligand™ ? Moligand™ — Aladdin's line of ligands and bioactive small molecules. Use for receptor, pathway, and binding studies needing defined small-molecule tools. ≥98%
    Out of Stock Item #: P339953
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    IUPAC Name
    1-[10-[3-[4-(2-hydroxyethyl)piperidin-1-yl]propyl]phenothiazin-2-yl]ethanone
    SMILES
    CC(=O)C1=CC2=C(C=C1)SC3=CC=CC=C3N2CCCN4CCC(CC4)CCO
    InChIKey
    BTFMCMVEUCGQDX-UHFFFAOYSA-N
    InChI
    1S/C24H30N2O2S/c1-18(28)20-7-8-24-22(17-20)26(21-5-2-3-6-23(21)29-24)13-4-12-25-14-9-19(10-15-25)11-16-27/h2-3,5-8,17,19,27H,4,9-16H2,1H3
    Synonyms
    HMS2230G17 | SR-01000841199 | 1-(10-{3-[4-(2-hydroxyethyl)-1-piperidinyl]propyl}-10H-phenothiazin-2-yl)ethanone | 1-(...
  6. Antazoline
    CAS: 91-75-8 EC Number: 202-094-0 Formula: C17H19N3 Molecular Weight: 265.35
    Moligand™ ? Moligand™ — Aladdin's line of ligands and bioactive small molecules. Use for receptor, pathway, and binding studies needing defined small-molecule tools. ≥98%
    In Stock Item #: A353004
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    N-benzyl-N-(4,5-dihydro-1H-imidazol-2-ylmethyl)aniline
    SMILES
    C1CN=C(N1)CN(CC2=CC=CC=C2)C3=CC=CC=C3
    InChIKey
    REYFJDPCWQRWAA-UHFFFAOYSA-N
    InChI
    1S/C17H19N3/c1-3-7-15(8-4-1)13-20(14-17-18-11-12-19-17)16-9-5-2-6-10-16/h1-10H,11-14H2,(H,18,19)
    Synonyms
    Antazolinum | Azalone | Spectrum2_001259 | 2-Phenyl-benzyl-amino-methylimidazolin | HY-B1067A | SBI-0051285.P003 | KB...
  7. Maprotiline, Channel blocker of K ir3.2;Channel blocker of K ir3.4;Inhibitor of NET;Channel blocker of TRPM3
    CAS: 10262-69-8 EC Number: 233-599-4 Formula: C20H23N Molecular Weight: 277.40
    Moligand™ ? Moligand™ — Aladdin's line of ligands and bioactive small molecules. Use for receptor, pathway, and binding studies needing defined small-molecule tools. ≥98%
    In Stock Item #: M338146
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    IUPAC Name
    N-methyl-3-(1-tetracyclo[6.6.2.02,7.09,14]hexadeca-2,4,6,9,11,13-hexaenyl)propan-1-amine
    SMILES
    CNCCCC12CCC(C3=CC=CC=C31)C4=CC=CC=C24
    InChIKey
    QSLMDECMDJKHMQ-UHFFFAOYSA-N
    InChI
    1S/C20H23N/c1-21-14-6-12-20-13-11-15(16-7-2-4-9-18(16)20)17-8-3-5-10-19(17)20/h2-5,7-10,15,21H,6,11-14H2,1H3
    Synonyms
    Maprotylina | DB00934 | 3-(9,10-ethanoanthracen-9(10H)-yl)-N-methylpropan-1-amine | NCGC00015708-05 | NCGC00015708-11...
  8. NVS-PAK1-1
    CAS: 1783816-74-9 PubChem CID: 137125241 Formula: C23H25ClF3N5O Molecular Weight: 479.93
    In Stock Item #: N275945
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    IUPAC Name
    (3S)-3-[[8-chloro-11-(2,2-difluoroethyl)-3-fluoro-5H-benzo[b][1,4]benzodiazepin-6-ylidene]amino]-N-propan-2-ylpyrrolidine-1-carboxamide
    SMILES
    CC(C)NC(=O)N1CCC(C1)N=C2C3=C(C=CC(=C3)Cl)N(C4=C(N2)C=C(C=C4)F)CC(F)F
    InChIKey
    OINGHOPGNMYCAB-INIZCTEOSA-N
    InChI
    1S/C23H25ClF3N5O/c1-13(2)28-23(33)31-8-7-16(11-31)29-22-17-9-14(24)3-5-19(17)32(12-21(26)27)20-6-4-15(25)10-18(20)30-22/h3-6,9-10,13,16,21H,7-8,11-12Hshow more
    Synonyms
    (S)-3-(2-Chloro-5-(2,2-difluoroethyl)-8-fluoro-5H-dibenzo[b,e][1,4]diazepin-11-ylamino)-N-isopropylpyrrolidine-1-carb...
  9. Rapamycin
    CAS: 53123-88-9 EC Number: 610-965-5 Formula: C51H79NO13 Molecular Weight: 914.19
    Moligand™ ? Moligand™ — Aladdin's line of ligands and bioactive small molecules. Use for receptor, pathway, and binding studies needing defined small-molecule tools. ≥95%(HPLC)
    In Stock Item #: S293790
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    IUPAC Name
    (1R,9S,12S,15R,16E,18R,19R,21R,23S,24E,26E,28E,30S,32S,35R)-1,18-dihydroxy-12-[(2R)-1-[(1S,3R,4R)-4-hydroxy-3-methoxycyclohexyl]propan-2-yl]-19,30-dimshow more
    SMILES
    CC1CCC2CC(C(=CC=CC=CC(CC(C(=O)C(C(C(=CC(C(=O)CC(OC(=O)C3CCCCN3C(=O)C(=O)C1(O2)O)C(C)CC4CCC(C(C4)OC)O)C)C)O)OC)C)C)C)OC
    InChIKey
    QFJCIRLUMZQUOT-HPLJOQBZSA-N
    InChI
    1S/C51H79NO13/c1-30-16-12-11-13-17-31(2)42(61-8)28-38-21-19-36(7)51(60,65-38)48(57)49(58)52-23-15-14-18-39(52)50(59)64-43(33(4)26-37-20-22-40(53)44(27show more
    Synonyms
    AY 22989 | AY-22989 | CHEBI:9168 | EC 610-965-5 | HMS2089A21 | RAPA | (1R,9S,12S,15R,16E,18R,19R,21R,23S,24E,26E,28E,...
  10. Ro 6842262
    CAS: 1396006-71-5 PubChem CID: 71265339 Formula: C28H26N4O4 Molecular Weight: 482.53
    Out of Stock Item #: R287720
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    IUPAC Name
    1-[4-[4-[4-methyl-5-[[(1R)-1-phenylethoxy]carbonylamino]triazol-1-yl]phenyl]phenyl]cyclopropane-1-carboxylic acid
    SMILES
    CC1=C(N(N=N1)C2=CC=C(C=C2)C3=CC=C(C=C3)C4(CC4)C(=O)O)NC(=O)OC(C)C5=CC=CC=C5
    InChIKey
    PXQUHYSYFWQRMF-LJQANCHMSA-N
    InChI
    1S/C28H26N4O4/c1-18-25(29-27(35)36-19(2)20-6-4-3-5-7-20)32(31-30-18)24-14-10-22(11-15-24)21-8-12-23(13-9-21)28(16-17-28)26(33)34/h3-15,19H,16-17H2,1-2show more
    Synonyms
    1-[4'-[4-Methyl-5-[[[(1R)-1-phenylethoxy]carbonylamino]-1H-1,2,3-triazol-1-yl][1,1'-biphenyl]-4-yl]cyclopropanecarbox...
  11. Rapamycin
    CAS: 53123-88-9 EC Number: 610-965-5 Formula: C51H79NO13 Molecular Weight: 914.19
    Moligand™ ? Moligand™ — Aladdin's line of ligands and bioactive small molecules. Use for receptor, pathway, and binding studies needing defined small-molecule tools. ≥98%(HPLC)
    In Stock Item #: S115842
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    Technical Identifiers
    IUPAC Name
    (1R,9S,12S,15R,16E,18R,19R,21R,23S,24E,26E,28E,30S,32S,35R)-1,18-dihydroxy-12-[(2R)-1-[(1S,3R,4R)-4-hydroxy-3-methoxycyclohexyl]propan-2-yl]-19,30-dimshow more
    SMILES
    CC1CCC2CC(C(=CC=CC=CC(CC(C(=O)C(C(C(=CC(C(=O)CC(OC(=O)C3CCCCN3C(=O)C(=O)C1(O2)O)C(C)CC4CCC(C(C4)OC)O)C)C)O)OC)C)C)C)OC
    InChIKey
    QFJCIRLUMZQUOT-HPLJOQBZSA-N
    InChI
    1S/C51H79NO13/c1-30-16-12-11-13-17-31(2)42(61-8)28-38-21-19-36(7)51(60,65-38)48(57)49(58)52-23-15-14-18-39(52)50(59)64-43(33(4)26-37-20-22-40(53)44(27show more
    Synonyms
    AY 22989 | AY-22989 | CHEBI:9168 | EC 610-965-5 | HMS2089A21 | RAPA | (1R,9S,12S,15R,16E,18R,19R,21R,23S,24E,26E,28E,...
  12. Olanzapine, D2-like dopamine receptor antagonist
    CAS: 132539-06-1 EC Number: 603-618-4 Formula: C17H20N4S Molecular Weight: 312.43
    Solid Moligand™ ? Moligand™ — Aladdin's line of ligands and bioactive small molecules. Use for receptor, pathway, and binding studies needing defined small-molecule tools. ≥99%
    In Stock Item #: O126519
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    IUPAC Name
    2-methyl-4-(4-methylpiperazin-1-yl)-10H-thieno[2,3-b][1,5]benzodiazepine
    SMILES
    CC1=CC2=C(S1)NC3=CC=CC=C3N=C2N4CCN(CC4)C
    InChIKey
    KVWDHTXUZHCGIO-UHFFFAOYSA-N
    InChI
    1S/C17H20N4S/c1-12-11-13-16(21-9-7-20(2)8-10-21)18-14-5-3-4-6-15(14)19-17(13)22-12/h3-6,11,19H,7-10H2,1-2H3
    Synonyms
    NSC_4585 | Olanzapine Teva | 2-Methyl-4-(4-methylpiperazin-1-yl)-10H-benzo[b]thieno[2,3-e][1,4]diazepine | OLANZAPIN...
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