ATP-sensitive inward rectifier potassium channel 11 (KCNJ11)

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  1. Glyburide, Sulfonylurea receptor 1, Kir6.2 blocker
    CAS: 10238-21-8 EC Number: 233-570-6 Formula: C23H28ClN3O5S Molecular Weight: 494.00
    Moligand™ ? Moligand™ — Aladdin's line of ligands and bioactive small molecules. Use for receptor, pathway, and binding studies needing defined small-molecule tools. ≥99%
    In Stock Item #: G127198
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    IUPAC Name
    5-chloro-N-[2-[4-(cyclohexylcarbamoylsulfamoyl)phenyl]ethyl]-2-methoxybenzamide
    SMILES
    COC1=C(C=C(C=C1)Cl)C(=O)NCCC2=CC=C(C=C2)S(=O)(=O)NC(=O)NC3CCCCC3
    InChIKey
    ZNNLBTZKUZBEKO-UHFFFAOYSA-N
    InChI
    1S/C23H28ClN3O5S/c1-32-21-12-9-17(24)15-20(21)22(28)25-14-13-16-7-10-19(11-8-16)33(30,31)27-23(29)26-18-5-3-2-4-6-18/h7-12,15,18H,2-6,13-14H2,1H3,(H,2show more
    Synonyms
    Bastiverit | Daonil | Semi-daonil | Euglucan | Glucolon | Glibenil | glyburide | Duraglucon | Glibenclamide | Glybenc...
  2. Cromakalim, Activator of K ir6.1;Activator of K ir6.2;Channel blocker of K v1.7;Channel blocker of K v3.1
    CAS: 94470-67-4 Formula: C16H18N2O3 Molecular Weight: 286.33
    Moligand™ ? Moligand™ — Aladdin's line of ligands and bioactive small molecules. Use for receptor, pathway, and binding studies needing defined small-molecule tools. ≥99%
    Out of Stock Item #: C274992
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    IUPAC Name
    3-hydroxy-2,2-dimethyl-4-(2-oxopyrrolidin-1-yl)-3,4-dihydrochromene-6-carbonitrile
    SMILES
    CC1(C(C(C2=C(O1)C=CC(=C2)C#N)N3CCCC3=O)O)C
    InChIKey
    TVZCRIROJQEVOT-UHFFFAOYSA-N
    InChI
    1S/C16H18N2O3/c1-16(2)15(20)14(18-7-3-4-13(18)19)11-8-10(9-17)5-6-12(11)21-16/h5-6,8,14-15,20H,3-4,7H2,1-2H3
    Synonyms
    GTPL2413 | (+/-)-cromakalim | 2H-Benzopyran-6-carbonitrile, 3,4-dihydro-3-hydroxy-2,2-dimethyl-4-(2-oxo-1-pyrrolidiny...
  3. P1075
    CAS: 60559-98-0 EC Number: 690-021-7 PubChem CID: 43345 Formula: C12H17N5 Molecular Weight: 231.30
    In Stock Item #: P287039
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    IUPAC Name
    1-cyano-2-(2-methylbutan-2-yl)-3-pyridin-3-ylguanidine
    SMILES
    CCC(C)(C)N=C(NC#N)NC1=CN=CC=C1
    InChIKey
    HKZNADVVGXKQDL-UHFFFAOYSA-N
    InChI
    1S/C12H17N5/c1-4-12(2,3)17-11(15-9-13)16-10-6-5-7-14-8-10/h5-8H,4H2,1-3H3,(H2,15,16,17)
    Synonyms
    BRN 0480738 | FT-0640699 | N-cyano-N'-(1,1-dimethylpropyl)-N'-3-pyridinyl-guanidine | CAS_60559-98-0 | NCGC00025121-0...
  4. Diazoxide, Activator of K ir6.1;Activator of K ir6.2
    CAS: 364-98-7 EC Number: 206-668-1 Formula: C8H7ClN2O2S Molecular Weight: 230.67
    Moligand™ ? Moligand™ — Aladdin's line of ligands and bioactive small molecules. Use for receptor, pathway, and binding studies needing defined small-molecule tools. ≥98%
    In Stock Item #: D136582
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    IUPAC Name
    7-chloro-3-methyl-4H-1λ6,2,4-benzothiadiazine 1,1-dioxide
    SMILES
    CC1=NS(=O)(=O)C2=C(N1)C=CC(=C2)Cl
    InChIKey
    GDLBFKVLRPITMI-UHFFFAOYSA-N
    InChI
    1S/C8H7ClN2O2S/c1-5-10-7-3-2-6(9)4-8(7)14(12,13)11-5/h2-4H,1H3,(H,10,11)
    Synonyms
    MFCD00078578 | Diazoxido | EINECS 206-668-1 | SMR000058392 | 7-Chloro-3-methyl-2H-1,4-benzothiadiazine 1,1-dioxide | ...
  5. Diazoxide, Activator of K ir6.1;Activator of K ir6.2
    CAS: 364-98-7 EC Number: 206-668-1 Formula: C8H7ClN2O2S Molecular Weight: 230.67
    Moligand™ ? Moligand™ — Aladdin's line of ligands and bioactive small molecules. Use for receptor, pathway, and binding studies needing defined small-molecule tools. 10mM in DMSO
    In Stock Item #: D423637
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    Technical Identifiers
    IUPAC Name
    7-chloro-3-methyl-4H-1λ6,2,4-benzothiadiazine 1,1-dioxide
    SMILES
    CC1=NS(=O)(=O)C2=C(N1)C=CC(=C2)Cl
    InChIKey
    GDLBFKVLRPITMI-UHFFFAOYSA-N
    InChI
    1S/C8H7ClN2O2S/c1-5-10-7-3-2-6(9)4-8(7)14(12,13)11-5/h2-4H,1H3,(H,10,11)
    Synonyms
    diazoxide|364-98-7|Proglycem|Hyperstat|Hypertonalum|Eudemine|Proglicem|Dizoxide|Mutabase|7-Chloro-3-methyl-2H-1,2,4-b...
  6. Glyburide (Glibenclamide), Sulfonylurea receptor 1, Kir6.2 blocker
    CAS: 10238-21-8 EC Number: 233-570-6 Formula: C23H28ClN3O5S Molecular Weight: 494.00
    Moligand™ ? Moligand™ — Aladdin's line of ligands and bioactive small molecules. Use for receptor, pathway, and binding studies needing defined small-molecule tools. 10mM in DMSO
    In Stock Item #: G407851
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    Technical Identifiers
    Synonyms
    5-​chloro-​N-​[2-​[4-​[[[(cyclohexylamino)​carbonyl]​amino]​sulfonyl]​phenyl]​ethyl]​-​2-​methoxy-benzamide
  7. VU0071063
    CAS: 333415-38-6 PubChem CID: 590142 Formula: C18H22N4O2 Molecular Weight: 326.39
    Out of Stock Item #: V413696
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    IUPAC Name
    7-[(4-tert-butylphenyl)methyl]-1,3-dimethylpurine-2,6-dione
    SMILES
    CC(C)(C)C1=CC=C(C=C1)CN2C=NC3=C2C(=O)N(C(=O)N3C)C
    InChIKey
    ZFZAIHKQJBMYLO-UHFFFAOYSA-N
    InChI
    1S/C18H22N4O2/c1-18(2,3)13-8-6-12(7-9-13)10-22-11-19-15-14(22)16(23)21(5)17(24)20(15)4/h6-9,11H,10H2,1-5H3
  8. BMS-191095
    CAS: 166095-21-2 PubChem CID: 9822753 Formula: C22H21ClN4O2 Molecular Weight: 408.88
    Out of Stock Item #: B648805
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    IUPAC Name
    (3R,4S)-4-[4-chloro-N-(1H-imidazol-2-ylmethyl)anilino]-3-hydroxy-2,2-dimethyl-3,4-dihydrochromene-6-carbonitrile
    SMILES
    CC1(C(C(C2=C(O1)C=CC(=C2)C#N)N(CC3=NC=CN3)C4=CC=C(C=C4)Cl)O)C
    InChIKey
    SMIKIPXIDLITMP-LEWJYISDSA-N
    InChI
    1S/C22H21ClN4O2/c1-22(2)21(28)20(17-11-14(12-24)3-8-18(17)29-22)27(13-19-25-9-10-26-19)16-6-4-15(23)5-7-16/h3-11,20-21,28H,13H2,1-2H3,(H,25,26)/t20-,2show more
    Synonyms
    AKOS030526638 | K6V527OYN8 | (3R,4S)-4-[4-chloro-N-(1H-imidazol-2-ylmethyl)anilino]-3-hydroxy-2,2-dimethyl-3,4-dihydr...
  9. VU041
    CAS: 332943-64-3 PubChem CID: 1129704 Formula: C19H20F3N3O Molecular Weight: 363.38
    Solid Moligand™ ? Moligand™ — Aladdin's line of ligands and bioactive small molecules. Use for receptor, pathway, and binding studies needing defined small-molecule tools. ≥98%
    Out of Stock Item #: V649263
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    IUPAC Name
    1-(3,4-dihydro-2H-quinolin-1-yl)-2-[3-(trifluoromethyl)-4,5,6,7-tetrahydroindazol-1-yl]ethanone
    SMILES
    C1CCC2=C(C1)C(=NN2CC(=O)N3CCCC4=CC=CC=C43)C(F)(F)F
    InChIKey
    DLAGRCZUELSZFG-UHFFFAOYSA-N
    InChI
    1S/C19H20F3N3O/c20-19(21,22)18-14-8-2-4-10-16(14)25(23-18)12-17(26)24-11-5-7-13-6-1-3-9-15(13)24/h1,3,6,9H,2,4-5,7-8,10-12H2
    Synonyms
    1,2,3,4-Tetrahydro-1-[[4,5,6,7-tetrahydro-3-(trifluoromethyl)-1H-indazol-1-yl]acetyl]-quinoline | 1-(3,4-Dihydroquino...
  10. Tifenazoxide
    CAS: 279215-43-9 PubChem CID: 135410911 Formula: C9H10ClN3O2S2 Molecular Weight: 291.78
    Out of Stock Item #: T647796
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    IUPAC Name
    6-chloro-N-(1-methylcyclopropyl)-1,1-dioxo-4H-thieno[3,2-e][1,2,4]thiadiazin-3-imine
    SMILES
    CC1(CC1)N=C2NC3=C(SC(=C3)Cl)S(=O)(=O)N2
    InChIKey
    KYSFUHHFTIGRJN-UHFFFAOYSA-N
    InChI
    1S/C9H10ClN3O2S2/c1-9(2-3-9)12-8-11-5-4-6(10)16-7(5)17(14,15)13-8/h4H,2-3H2,1H3,(H2,11,12,13)
    Synonyms
    6-Chloro-3-((1-methylcyclopropyl)amino)-2H-thieno[3,2-e][1,2,4]thiadiazine 1,1-dioxide | 6-Chloro-3-((1-methylcyclopr...
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