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Glutamate receptor ionotropic, kainate 1 (GRIK1)

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  1. Tezampanel, Antagonist of GluA1;Antagonist of GluA2;Antagonist of GluA3;Antagonist of GluA4
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    Tezampanel, Antagonist of GluA1;Antagonist of GluA2;Antagonist of GluA3;Antagonist of GluA4
    CAS: 154652-83-2 Formula: C13H21N5O2 Molecular Weight: 279.34
    Moligand™ ? Moligand™ — Aladdin's line of ligands and bioactive small molecules. Use for receptor, pathway, and binding studies needing defined small-molecule tools.
    Out of Stock Item #: T125750
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    IUPAC Name
    (3S,4aR,6R,8aR)-6-[2-(2H-tetrazol-5-yl)ethyl]-1,2,3,4,4a,5,6,7,8,8a-decahydroisoquinoline-3-carboxylic acid
    SMILES
    C1CC2CNC(CC2CC1CCC3=NNN=N3)C(=O)O
    InChIKey
    ZXFRFPSZAKNPQQ-YTWAJWBKSA-N
    InChI
    1S/C13H21N5O2/c19-13(20)11-6-10-5-8(1-3-9(10)7-14-11)2-4-12-15-17-18-16-12/h8-11,14H,1-7H2,(H,19,20)(H,15,16,17,18)/t8-,9+,10-,11+/m1/s1
    Synonyms
    BDBM50494341 | TEZAMPANEL ANHYDROUS | Tezampanel, anhydrous | 1-Methyl-2-phenylethylamine | LY 293558 | ly215490 | GA...
  2. NS 3763, Antagonist of GluK1
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    NS 3763, Antagonist of GluK1
    CAS: 70553-45-6 EC Number: 635-331-5 Formula: C22H16N2O6 Molecular Weight: 404.38
    Moligand™ ? Moligand™ — Aladdin's line of ligands and bioactive small molecules. Use for receptor, pathway, and binding studies needing defined small-molecule tools. ≥98%(HPLC)
    Out of Stock Item #: N288816
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    IUPAC Name
    4,6-dibenzamidobenzene-1,3-dicarboxylic acid
    SMILES
    C1=CC=C(C=C1)C(=O)NC2=CC(=C(C=C2C(=O)O)C(=O)O)NC(=O)C3=CC=CC=C3
    InChIKey
    UUDYZUDTQPLDDP-UHFFFAOYSA-N
    InChI
    1S/C22H16N2O6/c25-19(13-7-3-1-4-8-13)23-17-12-18(16(22(29)30)11-15(17)21(27)28)24-20(26)14-9-5-2-6-10-14/h1-12H,(H,23,25)(H,24,26)(H,27,28)(H,29,30)
    Synonyms
    NCGC00092326-01 | UNII-R4HH3BUP3T | NS 3763 | NS3763 | NS-3763 | 4,6-Dibenzamidoisophthalic acid | Q27088064 | BDBM50...
  3. NBQX
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    NBQX
    CAS: 118876-58-7 EC Number: 621-100-6 Formula: C12H8N4O6S Molecular Weight: 336.28
    ≥99%
    In Stock Item #: N274693
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    IUPAC Name
    6-nitro-2,3-dioxo-1,4-dihydrobenzo[f]quinoxaline-7-sulfonamide
    SMILES
    C1=CC2=C3C(=CC(=C2C(=C1)S(=O)(=O)N)[N+](=O)[O-])NC(=O)C(=O)N3
    InChIKey
    UQNAFPHGVPVTAL-UHFFFAOYSA-N
    InChI
    1S/C12H8N4O6S/c13-23(21,22)8-3-1-2-5-9(8)7(16(19)20)4-6-10(5)15-12(18)11(17)14-6/h1-4H,(H,14,17)(H,15,18)(H2,13,21,22)
    Synonyms
    2,3-Dihydroxy-6-nitro-benzo[f]quinoxaline-7-sulfonic acid amide | BPBio1_001312 | SR-01000597617-1 | NBQX hydrate | B...
  4. SYM 2081, Inhibitor of Excitatory amino acid transporter 2;Agonist of GluK1;Agonist of GluK2;Agonist of GluK3;Agonist of GluK4;Agonist of GluK5
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    SYM 2081, Inhibitor of Excitatory amino acid transporter 2;Agonist of GluK1;Agonist of GluK2;Agonist of GluK3;Agonist of GluK4;Agonist of GluK5
    CAS: 31137-74-3 PubChem CID: 95883 Formula: C6H11NO4 Molecular Weight: 161.16
    Moligand™ ? Moligand™ — Aladdin's line of ligands and bioactive small molecules. Use for receptor, pathway, and binding studies needing defined small-molecule tools. ≥97%(HPLC)
    In Stock Item #: S288041
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    IUPAC Name
    (2S,4R)-2-amino-4-methylpentanedioic acid
    SMILES
    CC(CC(C(=O)O)N)C(=O)O
    InChIKey
    KRKRAOXTGDJWNI-DMTCNVIQSA-N
    InChI
    1S/C6H11NO4/c1-3(5(8)9)2-4(7)6(10)11/h3-4H,2,7H2,1H3,(H,8,9)(H,10,11)/t3-,4+/m1/s1
    Synonyms
    XH88WJG9LJ | 4-Methyl-DL-glutamic acid, erythro- | L-Glutamic acid, 4-methyl-, (4R)- | HY-101310 | threo-gamma-Methyl...
  5. Kainic acid - Moligand™, ≥98% CAS No(487-79-6) by Aladdin Scientific
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    Kainic acid
    CAS: 487-79-6 Formula: C10H15NO4 Molecular Weight: 213.233
    Solid Moligand™ ? Moligand™ — Aladdin's line of ligands and bioactive small molecules. Use for receptor, pathway, and binding studies needing defined small-molecule tools. ≥98%
    In Stock Item #: K303803
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    IUPAC Name
    (2S,3S,4S)-3-(carboxymethyl)-4-prop-1-en-2-ylpyrrolidine-2-carboxylic acid
    SMILES
    CC(=C)C1CNC(C1CC(=O)O)C(=O)O
    InChIKey
    VLSMHEGGTFMBBZ-OOZYFLPDSA-N
    InChI
    1S/C10H15NO4/c1-5(2)7-4-11-9(10(14)15)6(7)3-8(12)13/h6-7,9,11H,1,3-4H2,2H3,(H,12,13)(H,14,15)/t6-,7+,9-/m0/s1
    Synonyms
    Acide kainique | Digenic acid | Helminal | L-alpha-Kainic acid | Kainsaeure | Digenin | Acidum kainicum | Kainate | A...
  6. Kainic acid, Agonist of GluK1;Agonist of GluK2;Agonist of GluK3;Agonist of GluK4;Agonist of GluK5
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    Kainic acid, Agonist of GluK1;Agonist of GluK2;Agonist of GluK3;Agonist of GluK4;Agonist of GluK5
    CAS: 487-79-6 Formula: C10H15NO4 Molecular Weight: 213.233
    Liquid Moligand™ ? Moligand™ — Aladdin's line of ligands and bioactive small molecules. Use for receptor, pathway, and binding studies needing defined small-molecule tools. 10mM in DMSO
    In Stock Item #: K276587
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    Technical Identifiers
    IUPAC Name
    (2S,3S,4S)-3-(carboxymethyl)-4-prop-1-en-2-ylpyrrolidine-2-carboxylic acid
    SMILES
    CC(=C)C1CNC(C1CC(=O)O)C(=O)O
    InChIKey
    VLSMHEGGTFMBBZ-OOZYFLPDSA-N
    InChI
    1S/C10H15NO4/c1-5(2)7-4-11-9(10(14)15)6(7)3-8(12)13/h6-7,9,11H,1,3-4H2,2H3,(H,12,13)(H,14,15)/t6-,7+,9-/m0/s1
    Synonyms
    Acide kainique | Digenic acid | Helminal | L-alpha-Kainic acid | Digenin | kainic acid | Kainate | Acido kainico | Di...
  7. (RS)-AMPA - Moligand™, ≥98% CAS No(77521-29-0) by Aladdin Scientific
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    (RS)-AMPA, Agonist of GluA1;Agonist of GluA2;Agonist of GluA3;Agonist of GluA4
    CAS: 77521-29-0 Formula: C7H10N2O4·H2O Molecular Weight: 204.19
    Moligand™ ? Moligand™ — Aladdin's line of ligands and bioactive small molecules. Use for receptor, pathway, and binding studies needing defined small-molecule tools. ≥98%
    In Stock Item #: R288477
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    IUPAC Name
    2-amino-3-(5-methyl-3-oxo-1,2-oxazol-4-yl)propanoic acid
    SMILES
    CC1=C(C(=O)NO1)CC(C(=O)O)N
    InChIKey
    UUDAMDVQRQNNHZ-UHFFFAOYSA-N
    InChI
    1S/C7H10N2O4/c1-3-4(6(10)9-13-3)2-5(8)7(11)12/h5H,2,8H2,1H3,(H,9,10)(H,11,12)
    Synonyms
    GTPL4077 | (+/-)-alpha-AMINO-3-HYDROXY-5-METHYL-4-ISOXAZOLEPROPIONIC ACID | (R)-2-Amino-3-(3-hydroxy-5-methyl-isoxazo...
  8. NBQX
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    NBQX
    CAS: 118876-58-7 EC Number: 621-100-6 Formula: C12H8N4O6S Molecular Weight: 336.28
    10mM in DMSO
    In Stock Item #: N420833
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    Technical Identifiers
    IUPAC Name
    6-nitro-2,3-dioxo-1,4-dihydrobenzo[f]quinoxaline-7-sulfonamide
    SMILES
    C1=CC2=C3C(=CC(=C2C(=C1)S(=O)(=O)N)[N+](=O)[O-])NC(=O)C(=O)N3
    InChIKey
    UQNAFPHGVPVTAL-UHFFFAOYSA-N
    InChI
    1S/C12H8N4O6S/c13-23(21,22)8-3-1-2-5-9(8)7(16(19)20)4-6-10(5)15-12(18)11(17)14-6/h1-4H,(H,14,17)(H,15,18)(H2,13,21,22)
    Synonyms
    2,3-Dihydroxy-6-nitro-benzo[f]quinoxaline-7-sulfonic acid amide | BPBio1_001312 | SR-01000597617-1 | NBQX hydrate | B...
  9. NS1652 - ≥98% CAS No(1566-81-0) by Aladdin Scientific
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    NS1652
    CAS: 1566-81-0 Formula: C15H11F3N2O3 Molecular Weight: 324.25
    ≥98%
    In Stock Item #: N412826
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    Technical Identifiers
    IUPAC Name
    2-[[3-(trifluoromethyl)phenyl]carbamoylamino]benzoic acid
    SMILES
    C1=CC=C(C(=C1)C(=O)O)NC(=O)NC2=CC=CC(=C2)C(F)(F)F
    InChIKey
    CTNQAPPDQTYTHM-UHFFFAOYSA-N
    InChI
    1S/C15H11F3N2O3/c16-15(17,18)9-4-3-5-10(8-9)19-14(23)20-12-7-2-1-6-11(12)13(21)22/h1-8H,(H,21,22)(H2,19,20,23)
    Synonyms
    2-(3-(3-(Trifluoromethyl)phenyl)ureido)benzoic acid | 9B8X1YC8U2 | UNII-9B8X1YC8U2 | BDBM50137154 | NS1652 | NS-1652 ...
  10. no_selection
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    dysiherbaine, Agonist of GluK1;Agonist of GluK2;Agonist of GluK3;Agonist of GluK4;Agonist of GluK5
    CAS: 185245-55-0 PubChem CID: 9839436
    Moligand™ ? Moligand™ — Aladdin's line of ligands and bioactive small molecules. Use for receptor, pathway, and binding studies needing defined small-molecule tools.
    Out of Stock Item #: D610035
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    Technical Identifiers
    IUPAC Name
    (2R,3aR,6S,7R,7aR)-2-[(2S)-2-amino-2-carboxyethyl]-6-hydroxy-7-(methylamino)-hexahydro-2H-furo[3,2-b]pyran-2-carboxylic acid
    SMILES
    CN[C@@H]1[C@H](O)CO[C@H]2[C@@H]1O[C@@](C2)(C[C@@H](C(=O)O)N)C(=O)O
    InChIKey
    YUSZFKPLFIQTGF-FDNSHYBFSA-N
    InChI
    1S/C12H20N2O7/c1-14-8-6(15)4-20-7-3-12(11(18)19,21-9(7)8)2-5(13)10(16)17/h5-9,14-15H,2-4,13H2,1H3,(H,16,17)(H,18,19)/t5-,6+,7+,8+,9-,12+/m0/s1
  11. no_selection
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    [³H]AMPA, Agonist of GluA1;Agonist of GluA2;GluA3;Agonist of GluA4
    Moligand™ ? Moligand™ — Aladdin's line of ligands and bioactive small molecules. Use for receptor, pathway, and binding studies needing defined small-molecule tools.
    Out of Stock Item #: H614055
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    Technical Identifiers
    IUPAC Name
    2-amino-3-(5-methyl-3-oxo-2,3-dihydro-1,2-oxazol-4-yl)propanoic acid
    SMILES
    OC(=O)C(Cc1c(C)o[nH]c1=O)N
    InChIKey
    UUDAMDVQRQNNHZ-UHFFFAOYSA-N
    InChI
    1S/C7H10N2O4/c1-3-4(6(10)9-13-3)2-5(8)7(11)12/h5H,2,8H2,1H3,(H,9,10)(H,11,12)
    Synonyms
    GTPL4077 | (+/-)-alpha-AMINO-3-HYDROXY-5-METHYL-4-ISOXAZOLEPROPIONIC ACID | (R)-2-Amino-3-(3-hydroxy-5-methyl-isoxazo...
  12. 4-chloro-2-[(3-iodophenyl)carbamoylamino]benzoic Acid
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    4-chloro-2-[(3-iodophenyl)carbamoylamino]benzoic Acid
    CAS: 639009-97-5 PubChem CID: 10001987 Formula: C14H10ClIN2O3 Molecular Weight: 416.6
    Out of Stock Item #: C669058
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    Technical Identifiers
    IUPAC Name
    4-chloro-2-[(3-iodophenyl)carbamoylamino]benzoic acid
    SMILES
    C1=CC(=CC(=C1)I)NC(=O)NC2=C(C=CC(=C2)Cl)C(=O)O
    InChIKey
    HDVLBTNZJJUZTI-UHFFFAOYSA-N
    InChI
    1S/C14H10ClIN2O3/c15-8-4-5-11(13(19)20)12(6-8)18-14(21)17-10-3-1-2-9(16)7-10/h1-7H,(H,19,20)(H2,17,18,21)
    Synonyms
    4-chloro-2-[(3-iodophenyl)carbamoylamino]benzoic Acid | 4-chloro-2-{[(3-iodophenyl)carbamoyl]amino}benzoic acid | BDB...
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