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Nadph oxidase 5 (NOX5)

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  1. Celastrol, Inhibitor of regulator of G-protein signaling 17
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    Celastrol, Inhibitor of regulator of G-protein signaling 17
    CAS: 34157-83-0 EC Number: 636-472-5 Formula: C29H38O4 Molecular Weight: 450.61
    Analytical standard ? Analytical standard — certified-purity material for quantitative calibration. Use to prepare calibration standards and validate analytical methods. Moligand™ ? Moligand™ — Aladdin's line of ligands and bioactive small molecules. Use for receptor, pathway, and binding studies needing defined small-molecule tools. ≥98%
    In Stock Item #: C107671
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    Technical Identifiers
    IUPAC Name
    (2R,4aS,6aR,6aS,14aS,14bR)-10-hydroxy-2,4a,6a,6a,9,14a-hexamethyl-11-oxo-1,3,4,5,6,13,14,14b-octahydropicene-2-carboxylic acid
    SMILES
    CC1=C(C(=O)C=C2C1=CC=C3C2(CCC4(C3(CCC5(C4CC(CC5)(C)C(=O)O)C)C)C)C)O
    InChIKey
    KQJSQWZMSAGSHN-JJWQIEBTSA-N
    InChI
    1S/C29H38O4/c1-17-18-7-8-21-27(4,19(18)15-20(30)23(17)31)12-14-29(6)22-16-26(3,24(32)33)10-9-25(22,2)11-13-28(21,29)5/h7-8,15,22,31H,9-14,16H2,1-6H3,(show more
    Synonyms
    (2R,4aS,6aR,6aS,14aS,14bR)-10-hydroxy-2,4a,6a,6a,9,14a-hexamethyl-11-oxo-1,3,4,5,6,13,14,14b-octahydropicene-2-carbox...
  2. VAS 2870
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    VAS 2870
    CAS: 722456-31-7 EC Number: 804-251-4 PubChem CID: 4058452 Formula: C18H12N6OS Molecular Weight: 360.39
    ≥98%
    In Stock Item #: V276146
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    IUPAC Name
    2-(3-benzyltriazolo[4,5-d]pyrimidin-7-yl)sulfanyl-1,3-benzoxazole
    SMILES
    C1=CC=C(C=C1)CN2C3=C(C(=NC=N3)SC4=NC5=CC=CC=C5O4)N=N2
    InChIKey
    HZSOKHVVANONPV-UHFFFAOYSA-N
    InChI
    1S/C18H12N6OS/c1-2-6-12(7-3-1)10-24-16-15(22-23-24)17(20-11-19-16)26-18-21-13-8-4-5-9-14(13)25-18/h1-9,11H,10H2
    Synonyms
    XDB45631 | 1,3-benzoxazol-2-yl 3-benzyl-3H-[1,2,3]triazolo[4,5-d]pyrimidin-7-yl sulfide | NOX Inhibitor III, VAS2870 ...
  3. Diphenyleneiodonium chloride, Agonist of GPR3
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    Diphenyleneiodonium chloride, Agonist of GPR3
    CAS: 4673-26-1 EC Number: 805-298-3 PubChem CID: 2733504 Formula: C12H8ClI Molecular Weight: 314.55
    Moligand™ ? Moligand™ — Aladdin's line of ligands and bioactive small molecules. Use for receptor, pathway, and binding studies needing defined small-molecule tools. ≥97%
    In Stock Item #: D113448
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    Technical Identifiers
    IUPAC Name
    8-iodoniatricyclo[7.4.0.02,7]trideca-1(13),2,4,6,9,11-hexaene;chloride
    SMILES
    C1=CC=C2C(=C1)C3=CC=CC=C3[I+]2.[Cl-]
    InChIKey
    FCFZKAVCDNTYID-UHFFFAOYSA-M
    InChI
    1S/C12H8I.ClH/c1-3-7-11-9(5-1)10-6-2-4-8-12(10)13-11;/h1-8H;1H/q+1;/p-1
    Synonyms
    8-iodoniatricyclo[7.4.0.02,7]trideca-1(13),2,4,6,9,11-hexaene;chloride | 8-iodoniatricyclo[7.4.0.0^{2,7]trideca-1(13)...
  4. Ebselen, Antioxidant
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    Ebselen, Antioxidant
    CAS: 60940-34-3 EC Number: 612-054-8 Formula: C13H9NOSe Molecular Weight: 274.18
    Moligand™ ? Moligand™ — Aladdin's line of ligands and bioactive small molecules. Use for receptor, pathway, and binding studies needing defined small-molecule tools. ≥98%
    In Stock Item #: P137293
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    IUPAC Name
    2-phenyl-1,2-benzoselenazol-3-one
    SMILES
    C1=CC=C(C=C1)N2C(=O)C3=CC=CC=C3[Se]2
    InChIKey
    DYEFUKCXAQOFHX-UHFFFAOYSA-N
    InChI
    1S/C13H9NOSe/c15-13-11-8-4-5-9-12(11)16-14(13)10-6-2-1-3-7-10/h1-9H
    Synonyms
    Ebselen, cysteine modifier | HMS502P13 | Lopac-E-3520 | Prestwick0_000740 | SCHEMBL33829 | C042986 | NCGC00024072-04 ...
  5. Celastrol
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    Celastrol
    CAS: 34157-83-0 EC Number: 636-472-5 Formula: C29H38O4 Molecular Weight: 450.61
    Moligand™ ? Moligand™ — Aladdin's line of ligands and bioactive small molecules. Use for receptor, pathway, and binding studies needing defined small-molecule tools. ≥98%
    In Stock Item #: C107672
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    Technical Identifiers
    IUPAC Name
    (2R,4aS,6aR,6aS,14aS,14bR)-10-hydroxy-2,4a,6a,6a,9,14a-hexamethyl-11-oxo-1,3,4,5,6,13,14,14b-octahydropicene-2-carboxylic acid
    SMILES
    CC1=C(C(=O)C=C2C1=CC=C3C2(CCC4(C3(CCC5(C4CC(CC5)(C)C(=O)O)C)C)C)C)O
    InChIKey
    KQJSQWZMSAGSHN-JJWQIEBTSA-N
    InChI
    1S/C29H38O4/c1-17-18-7-8-21-27(4,19(18)15-20(30)23(17)31)12-14-29(6)22-16-26(3,24(32)33)10-9-25(22,2)11-13-28(21,29)5/h7-8,15,22,31H,9-14,16H2,1-6H3,(show more
    Synonyms
    (2R,4aS,6aR,6aS,14aS,14bR)-10-hydroxy-2,4a,6a,6a,9,14a-hexamethyl-11-oxo-1,3,4,5,6,13,14,14b-octahydropicene-2-carbox...
  6. Celastrol (NSC 70931), Inhibitor of regulator of G-protein signaling 17
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    Celastrol (NSC 70931), Inhibitor of regulator of G-protein signaling 17
    CAS: 34157-83-0 EC Number: 636-472-5 Formula: C29H38O4 Molecular Weight: 450.61
    Moligand™ ? Moligand™ — Aladdin's line of ligands and bioactive small molecules. Use for receptor, pathway, and binding studies needing defined small-molecule tools. 10mM in DMSO
    In Stock Item #: C408328
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    Technical Identifiers
    Synonyms
    Tripterine | (2R,4aS,6aS,12bR,14aS,14bR)-10-hydroxy-2,4a,6a,9,12b,14a-hexamethyl-11-oxo-1,2,3,4,4a,5,6,6a,11,12b,13,1...
  7. Diphenyleneiodonium chloride, Agonist of GPR3
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    Diphenyleneiodonium chloride, Agonist of GPR3
    CAS: 4673-26-1 EC Number: 805-298-3 PubChem CID: 2733504 Formula: C12H8ClI Molecular Weight: 314.55
    Moligand™ ? Moligand™ — Aladdin's line of ligands and bioactive small molecules. Use for receptor, pathway, and binding studies needing defined small-molecule tools. 10mM in DMSO
    In Stock Item #: D424096
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    Technical Identifiers
    IUPAC Name
    8-iodoniatricyclo[7.4.0.02,7]trideca-1(13),2,4,6,9,11-hexaene;chloride
    SMILES
    C1=CC=C2C(=C1)C3=CC=CC=C3[I+]2.[Cl-]
    InChIKey
    FCFZKAVCDNTYID-UHFFFAOYSA-M
    InChI
    1S/C12H8I.ClH/c1-3-7-11-9(5-1)10-6-2-4-8-12(10)13-11;/h1-8H;1H/q+1;/p-1
    Synonyms
    8-iodoniatricyclo[7.4.0.02,7]trideca-1(13),2,4,6,9,11-hexaene;chloride | 8-iodoniatricyclo[7.4.0.0^{2,7]trideca-1(13)...
  8. Ebselen, Antioxidant
    Wish List Compare
    Ebselen, Antioxidant
    CAS: 60940-34-3 EC Number: 612-054-8 Formula: C13H9NOSe Molecular Weight: 274.18
    Moligand™ ? Moligand™ — Aladdin's line of ligands and bioactive small molecules. Use for receptor, pathway, and binding studies needing defined small-molecule tools. 10mM in DMSO
    In Stock Item #: E425045
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    Technical Identifiers
    IUPAC Name
    2-phenyl-1,2-benzoselenazol-3-one
    SMILES
    C1=CC=C(C=C1)N2C(=O)C3=CC=CC=C3[Se]2
    InChIKey
    DYEFUKCXAQOFHX-UHFFFAOYSA-N
    InChI
    1S/C13H9NOSe/c15-13-11-8-4-5-9-12(11)16-14(13)10-6-2-1-3-7-10/h1-9H
    Synonyms
    ebselen|60940-34-3|2-Phenyl-1,2-benzisoselenazol-3(2H)-one|2-phenylbenzo[d][1,2]selenazol-3(2H)-one|Ebselenum|2-pheny...
  9. Setanaxib (GKT137831), Inhibitor of cytochrome b-245 beta chain;Inhibitor of NADPH oxidase 1;Inhibitor of NADPH oxidase 4;Inhibitor of NADPH oxidase 5
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    Setanaxib (GKT137831), Inhibitor of cytochrome b-245 beta chain;Inhibitor of NADPH oxidase 1;Inhibitor of NADPH oxidase 4;Inhibitor of NADPH oxidase 5
    CAS: 1218942-37-0 EC Number: 942-974-8 PubChem CID: 58496428 Formula: C21H19ClN4O2 Molecular Weight: 394.85
    Moligand™ ? Moligand™ — Aladdin's line of ligands and bioactive small molecules. Use for receptor, pathway, and binding studies needing defined small-molecule tools. 10mM in DMSO
    In Stock Item #: S407890
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    Synonyms
    GKT831 | 2-(2-chlorophenyl)-4-(3-(dimethylamino)phenyl)-5-methyl-1,2-dihydro-5H-pyrazolo[4,3-c]pyridine-3,6-dione
  10. Setanaxib (GKT137831), Inhibitor of cytochrome b-245 beta chain;Inhibitor of NADPH oxidase 1;Inhibitor of NADPH oxidase 4;Inhibitor of NADPH oxidase 5
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    Setanaxib (GKT137831), Inhibitor of cytochrome b-245 beta chain;Inhibitor of NADPH oxidase 1;Inhibitor of NADPH oxidase 4;Inhibitor of NADPH oxidase 5
    CAS: 1218942-37-0 EC Number: 942-974-8 PubChem CID: 58496428 Formula: C21H19ClN4O2 Molecular Weight: 394.85
    Moligand™ ? Moligand™ — Aladdin's line of ligands and bioactive small molecules. Use for receptor, pathway, and binding studies needing defined small-molecule tools. ≥99%
    In Stock Item #: S413718
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    Technical Identifiers
    IUPAC Name
    2-(2-chlorophenyl)-4-[3-(dimethylamino)phenyl]-5-methyl-1H-pyrazolo[4,3-c]pyridine-3,6-dione
    SMILES
    CN1C(=O)C=C2C(=C1C3=CC(=CC=C3)N(C)C)C(=O)N(N2)C4=CC=CC=C4Cl
    InChIKey
    RGYQPQARIQKJKH-UHFFFAOYSA-N
    InChI
    1S/C21H19ClN4O2/c1-24(2)14-8-6-7-13(11-14)20-19-16(12-18(27)25(20)3)23-26(21(19)28)17-10-5-4-9-15(17)22/h4-12,23H,1-3H3
    Synonyms
    DTXSID30153432 | SCHEMBL1302603 | 1H-Pyrazolo[4,3-c]pyridine-3,6(2H,5H)-dione, 2-(2-chlorophenyl)-4-[3-(dimethylamino...
  11. VAS 2870
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    VAS 2870
    CAS: 722456-31-7 EC Number: 804-251-4 PubChem CID: 4058452 Formula: C18H12N6OS Molecular Weight: 360.39
    10mM in DMSO
    In Stock Item #: V425664
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    Pricing & Pack Sizes
    Technical Identifiers
    IUPAC Name
    2-(3-benzyltriazolo[4,5-d]pyrimidin-7-yl)sulfanyl-1,3-benzoxazole
    SMILES
    C1=CC=C(C=C1)CN2C3=C(C(=NC=N3)SC4=NC5=CC=CC=C5O4)N=N2
    InChIKey
    HZSOKHVVANONPV-UHFFFAOYSA-N
    InChI
    1S/C18H12N6OS/c1-2-6-12(7-3-1)10-24-16-15(22-23-24)17(20-11-19-16)26-18-21-13-8-4-5-9-14(13)25-18/h1-9,11H,10H2
    Synonyms
    XDB45631 | 1,3-benzoxazol-2-yl 3-benzyl-3H-[1,2,3]triazolo[4,5-d]pyrimidin-7-yl sulfide | NOX Inhibitor III, VAS2870 ...
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