Potassium/sodium hyperpolarization-activated cyclic nucleotide-gated channel 4 (HCN4)

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  1. ZD7288
    CAS: 133059-99-1 PubChem CID: 123983 Formula: C15H21N4 •Cl Molecular Weight: 292.81
    In Stock Item #: Z274826
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    IUPAC Name
    N-ethyl-1,2-dimethyl-6-methylimino-N-phenylpyrimidin-4-amine;hydrochloride
    SMILES
    CCN(C1=CC=CC=C1)C2=CC(=NC)N(C(=N2)C)C.Cl
    InChIKey
    DUWKUHWHTPRMAP-UHFFFAOYSA-N
    InChI
    1S/C15H20N4.ClH/c1-5-19(13-9-7-6-8-10-13)15-11-14(16-3)18(4)12(2)17-15;/h6-11H,5H2,1-4H3;1H
    Synonyms
    BZ162628 | HB1152 | N-Ethyl-1,6-dihydro-1,2-dimethyl-6-(methylimino)-N-phenyl-4-pyrimidinamine monohydrochloride | ZD...
  2. AZD5718
    Moligand™ ? Moligand™ — Aladdin's line of ligands and bioactive small molecules. Use for receptor, pathway, and binding studies needing defined small-molecule tools.
    Out of Stock Item #: A607875
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    IUPAC Name
    (1R,2R)-2-[4-(5-methyl-1H-pyrazol-3-yl)benzoyl]-N-(4-oxo-6,7-dihydro-5H-pyrazolo[1,5-a]pyrazin-3-yl)cyclohexane-1-carboxamide
    SMILES
    O=C([C@@H]1CCCC[C@H]1C(=O)c1ccc(cc1)c1n[nH]c(c1)C)Nc1cnn2c1C(=O)NCC2
    InChIKey
    ROTWSDMXHVGAHZ-QZTJIDSGSA-N
    InChI
    1S/C24H26N6O3/c1-14-12-19(29-28-14)15-6-8-16(9-7-15)22(31)17-4-2-3-5-18(17)23(32)27-20-13-26-30-11-10-25-24(33)21(20)30/h6-9,12-13,17-18H,2-5,10-11H2,show more
    Synonyms
    AZD 5718 [WHO-DD] | HY-122908 | (1R,2R)-2-[4-(5-methyl-1H-pyrazol-3-yl)benzoyl]-N-(4-oxo-6,7-dihydro-5H-pyrazolo[1,5-...
  3. Ivabradine, Potassium/sodium hyperpolarization-activated cyclic nucleotide-gated channel 4 blocker
    CAS: 155974-00-8 PubChem CID: 132999 Formula: C27H36N2O5 Molecular Weight: 468.59
    Moligand™ ? Moligand™ — Aladdin's line of ligands and bioactive small molecules. Use for receptor, pathway, and binding studies needing defined small-molecule tools. ≥98%
    In Stock Item #: I611210
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    IUPAC Name
    3-[3-[[(7S)-3,4-dimethoxy-7-bicyclo[4.2.0]octa-1,3,5-trienyl]methyl-methylamino]propyl]-7,8-dimethoxy-2,5-dihydro-1H-3-benzazepin-4-one
    SMILES
    CN(CCCN1CCC2=CC(=C(C=C2CC1=O)OC)OC)CC3CC4=CC(=C(C=C34)OC)OC
    InChIKey
    ACRHBAYQBXXRTO-OAQYLSRUSA-N
    InChI
    1S/C27H36N2O5/c1-28(17-21-11-20-14-25(33-4)26(34-5)16-22(20)21)8-6-9-29-10-7-18-12-23(31-2)24(32-3)13-19(18)15-27(29)30/h12-14,16,21H,6-11,15,17H2,1-5show more
    Synonyms
    AB01566878_01 | AKOS015896494 | AT22349 | NCGC00181343-03 | S 16257 | 3-[3-({[(7S)-3,4-dimethoxybicyclo[4.2.0]octa-1,...
  4. Zatebradine, Channel blocker of HCN1;Channel blocker of HCN2;Channel blocker of HCN3;Channel blocker of HCN4
    CAS: 85175-67-3 Formula: C26H36N2O5 Molecular Weight: 456.57
    Moligand™ ? Moligand™ — Aladdin's line of ligands and bioactive small molecules. Use for receptor, pathway, and binding studies needing defined small-molecule tools. ≥98%
    Out of Stock Item #: Z614949
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    IUPAC Name
    3-[3-[2-(3,4-dimethoxyphenyl)ethyl-methylamino]propyl]-7,8-dimethoxy-2,5-dihydro-1H-3-benzazepin-4-one
    SMILES
    CN(CCCN1CCC2=CC(=C(C=C2CC1=O)OC)OC)CCC3=CC(=C(C=C3)OC)OC
    InChIKey
    KEDQCFRVSHYKLR-UHFFFAOYSA-N
    InChI
    1S/C26H36N2O5/c1-27(13-9-19-7-8-22(30-2)23(15-19)31-3)11-6-12-28-14-10-20-16-24(32-4)25(33-5)17-21(20)18-26(28)29/h7-8,15-17H,6,9-14,18H2,1-5H3
    Synonyms
    3-(3-((3,4-Dimethoxyphenethyl)(methyl)amino)propyl)-7,8-dimethoxy-4,5-dihydro-1H-benzo[d]azepin-2(3H)-one | 3-(3-{[2-...
  5. 4-Ethylphenylamino-1,2-dimethyl-6-methylaminopyrimidinium chloride
    Formula: C15H21ClN4 Molecular Weight: 292.81
    Out of Stock Item #: E669002
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    IUPAC Name
    4-N-ethyl-6-N,1,2-trimethyl-4-N-phenylpyrimidin-1-ium-4,6-diamine;chloride
    SMILES
    CCN(C1=CC=CC=C1)C2=CC(=[N+](C(=N2)C)C)NC.[Cl-]
    InChIKey
    DUWKUHWHTPRMAP-UHFFFAOYSA-N
    InChI
    1S/C15H20N4.ClH/c1-5-19(13-9-7-6-8-10-13)15-11-14(16-3)18(4)12(2)17-15;/h6-11H,5H2,1-4H3;1H
    Synonyms
    ICI D7288 | 4-ETHYLPHENYLAMINO-1,2-DIMETHYL-6-METHYLAMINOPYRIMIDINIUM CHLORIDE | 4-N-ethyl-6-N,1,2-trimethyl-4-N-phen...
  6. Zatebradine
    CAS: 85175-67-3 Formula: C26H36N2O5 Molecular Weight: 456.57
    Moligand™ ? Moligand™ — Aladdin's line of ligands and bioactive small molecules. Use for receptor, pathway, and binding studies needing defined small-molecule tools. 10 mM in DMSO
    Out of Stock Item #: Z1496306
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  7. ZD7288
    CAS: 133059-99-1 PubChem CID: 123983 Formula: C15H21N4 •Cl Molecular Weight: 292.81
    Moligand™ ? Moligand™ — Aladdin's line of ligands and bioactive small molecules. Use for receptor, pathway, and binding studies needing defined small-molecule tools. 10 mM in DMSO
    Out of Stock Item #: Z1493342
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