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Mitogen-activated protein kinase kinase kinase 19 (MAP3K19)

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  1. Lestaurtinib, Tyrosine-protein kinase receptor RET inhibitor
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    Lestaurtinib, Tyrosine-protein kinase receptor RET inhibitor
    CAS: 111358-88-4 Formula: C26H21N3O4 Molecular Weight: 439.46
    Solid Moligand™ ? Moligand™ — Aladdin's line of ligands and bioactive small molecules. Use for receptor, pathway, and binding studies needing defined small-molecule tools. ≥98%
    In Stock Item #: L275009
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    IUPAC Name
    (15S,16S,18R)-16-hydroxy-16-(hydroxymethyl)-15-methyl-28-oxa-4,14,19-triazaoctacyclo[12.11.2.115,18.02,6.07,27.08,13.019,26.020,25]octacosa-1,6,8,10,1show more
    SMILES
    CC12C(CC(O1)N3C4=CC=CC=C4C5=C6C(=C7C8=CC=CC=C8N2C7=C53)CNC6=O)(CO)O
    InChIKey
    UIARLYUEJFELEN-LROUJFHJSA-N
    InChI
    1S/C26H21N3O4/c1-25-26(32,12-30)10-18(33-25)28-16-8-4-2-6-13(16)20-21-15(11-27-24(21)31)19-14-7-3-5-9-17(14)29(25)23(19)22(20)28/h2-9,18,30,32H,10-12Hshow more
    Synonyms
    SPM-924 | (5S,6S,8R)-6-hydroxy-6-(hydroxymethyl)-5-methyl-7,8,14,15-tetrahydro-5H-16-oxa-4b,8a,14-triaza-5,8-methanod...
  2. BMS 345541
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    BMS 345541
    CAS: 445430-58-0 Formula: C14H17N5 Molecular Weight: 255.32
    ≥99%
    In Stock Item #: B275312
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    IUPAC Name
    N'-(1,8-dimethylimidazo[1,2-a]quinoxalin-4-yl)ethane-1,2-diamine
    SMILES
    CC1=CC2=C(C=C1)N=C(C3=NC=C(N23)C)NCCN
    InChIKey
    PSPFQEBFYXJZEV-UHFFFAOYSA-N
    InChI
    1S/C14H17N5/c1-9-3-4-11-12(7-9)19-10(2)8-17-14(19)13(18-11)16-6-5-15/h3-4,7-8H,5-6,15H2,1-2H3,(H,16,18)
    Synonyms
    Kinome_3215 | NCGC00165761-02 | AS-76298 | DTXSID60196216 | JEFFSOL GLYCERINE CARBONATE | N-(2-aminoethyl)-3,12-dimet...
  3. GDC-0879, Inhibitor of B-Raf proto-oncogene; serine/threonine kinase
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    GDC-0879, Inhibitor of B-Raf proto-oncogene; serine/threonine kinase
    CAS: 905281-76-7 Formula: C19H18N4O2 Molecular Weight: 334.37
    Moligand™ ? Moligand™ — Aladdin's line of ligands and bioactive small molecules. Use for receptor, pathway, and binding studies needing defined small-molecule tools. ≥96%
    In Stock Item #: G127893
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    IUPAC Name
    2-[4-[(1E)-1-hydroxyimino-2,3-dihydroinden-5-yl]-3-pyridin-4-ylpyrazol-1-yl]ethanol
    SMILES
    C1CC(=NO)C2=C1C=C(C=C2)C3=CN(N=C3C4=CC=NC=C4)CCO
    InChIKey
    DEZZLWQELQORIU-RELWKKBWSA-N
    InChI
    1S/C19H18N4O2/c24-10-9-23-12-17(19(21-23)13-5-7-20-8-6-13)15-1-3-16-14(11-15)2-4-18(16)22-25/h1,3,5-8,11-12,24-25H,2,4,9-10H2/b22-18+
    Synonyms
    SCHEMBL2467603 | 2,3-dihydro-5-(1-(2-hydroxyethyl)-3-(4-pyridinyl)-1h-pyrazol-4-yl)-1h-inden-1-one oxime | CCG-264821...
  4. BAY-985, Inhibitor of fms related receptor tyrosine kinase 3;Inhibitor of inhibitor of nuclear factor kappa B kinase subunit epsilon;Inhibitor of ribosomal protein S6 kinase A6;Inhibitor of serine/threonine kinase 17a;Inhibitor of TANK binding kinase 1
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    BAY-985, Inhibitor of fms related receptor tyrosine kinase 3;Inhibitor of inhibitor of nuclear factor kappa B kinase subunit epsilon;Inhibitor of ribosomal protein S6 kinase A6;Inhibitor of serine/threonine kinase 17a;Inhibitor of TANK binding kinase 1
    CAS: 2409479-29-2 Formula: C27H30F3N9O Molecular Weight: 553.58
    Moligand™ ? Moligand™ — Aladdin's line of ligands and bioactive small molecules. Use for receptor, pathway, and binding studies needing defined small-molecule tools. ≥98%
    In Stock Item #: B414279
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    IUPAC Name
    1-[4-[(1R)-1-[2-[[6-[6-(dimethylamino)pyrimidin-4-yl]-1H-benzimidazol-2-yl]amino]pyridin-4-yl]ethyl]piperazin-1-yl]-3,3,3-trifluoropropan-1-one
    SMILES
    CC(C1=CC(=NC=C1)NC2=NC3=C(N2)C=C(C=C3)C4=CC(=NC=N4)N(C)C)N5CCN(CC5)C(=O)CC(F)(F)F
    InChIKey
    HZRJHVDNTDBTOZ-QGZVFWFLSA-N
    InChI
    1S/C27H30F3N9O/c1-17(38-8-10-39(11-9-38)25(40)15-27(28,29)30)18-6-7-31-23(13-18)36-26-34-20-5-4-19(12-22(20)35-26)21-14-24(37(2)3)33-16-32-21/h4-7,12-show more
    Synonyms
    1-Propanone,1-[4-[(1R)-1-[2-[[6-[6-(dimethylamino)-4-pyrimidinyl]-1H-benzimidazol-2-yl]amino]-4-pyridinyl]ethyl]-1-pi...
  6. GDC-0879, Inhibitor of B-Raf proto-oncogene; serine/threonine kinase
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    GDC-0879, Inhibitor of B-Raf proto-oncogene; serine/threonine kinase
    CAS: 905281-76-7 Formula: C19H18N4O2 Molecular Weight: 334.37
    Moligand™ ? Moligand™ — Aladdin's line of ligands and bioactive small molecules. Use for receptor, pathway, and binding studies needing defined small-molecule tools. 10mM in DMSO
    In Stock Item #: G409101
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    Synonyms
    AR-00341677 | (E)-5-(1-(2-hydroxyethyl)-3-(pyridin-4-yl)-1H-pyrazol-4-yl)-2,3-dihydroinden-1-one oxime
  7. JH-X-119-01 - 10mM in DMSO CAS No(2227368-54-7) by Aladdin Scientific
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    JH-X-119-01
    CAS: 2227368-54-7 Formula: C25H20N6O3 Molecular Weight: 452.46
    Liquid 10mM in DMSO
    Out of Stock Item #: J580425
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    IUPAC Name
    N-[4-[[3-(prop-2-enoylamino)benzoyl]amino]phenyl]-6-(1H-pyrazol-5-yl)pyridine-2-carboxamide
    SMILES
    C=CC(=O)NC1=CC=CC(=C1)C(=O)NC2=CC=C(C=C2)NC(=O)C3=CC=CC(=N3)C4=CC=NN4
    InChIKey
    WQVPGYMGERDXLH-UHFFFAOYSA-N
    InChI
    1S/C25H20N6O3/c1-2-23(32)27-19-6-3-5-16(15-19)24(33)28-17-9-11-18(12-10-17)29-25(34)22-8-4-7-20(30-22)21-13-14-26-31-21/h2-15H,1H2,(H,26,31)(H,27,32)(show more
  8. JH-X-119-01
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    JH-X-119-01
    CAS: 2227368-54-7 Formula: C25H20N6O3 Molecular Weight: 452.46
    ≥97%
    In Stock Item #: J420000
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    Technical Identifiers
    IUPAC Name
    N-[4-[[3-(prop-2-enoylamino)benzoyl]amino]phenyl]-6-(1H-pyrazol-5-yl)pyridine-2-carboxamide
    SMILES
    C=CC(=O)NC1=CC=CC(=C1)C(=O)NC2=CC=C(C=C2)NC(=O)C3=CC=CC(=N3)C4=CC=NN4
    InChIKey
    WQVPGYMGERDXLH-UHFFFAOYSA-N
    InChI
    1S/C25H20N6O3/c1-2-23(32)27-19-6-3-5-16(15-19)24(33)28-17-9-11-18(12-10-17)29-25(34)22-8-4-7-20(30-22)21-13-14-26-31-21/h2-15H,1H2,(H,26,31)(H,27,32)(show more
  9. 4-Aminocinnoline-3-carboxamide
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    4-Aminocinnoline-3-carboxamide
    CAS: 38024-35-0 PubChem CID: 2814562 Formula: C9H8N4O Molecular Weight: 188.19
    ≥95%
    Out of Stock Item #: A701369
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    Technical Identifiers
    IUPAC Name
    4-aminocinnoline-3-carboxamide
    SMILES
    C1=CC=C2C(=C1)C(=C(N=N2)C(=O)N)N
    InChIKey
    FCYPWSQPDXUBPV-UHFFFAOYSA-N
    InChI
    1S/C9H8N4O/c10-7-5-3-1-2-4-6(5)12-13-8(7)9(11)14/h1-4H,(H2,10,12)(H2,11,14)
  10. CDK8/19-IN-1
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    CDK8/19-IN-1
    CAS: 1818427-07-4 PubChem CID: 126511854
    ≥98%
    Out of Stock Item #: C1424122
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    Technical Identifiers
    IUPAC Name
    8-[6-(2-methoxyethylcarbamoyl)pyridin-3-yl]oxy-4,5-dihydrothieno[3,4-g][1,2]benzothiazole-6-carboxamide
    SMILES
    COCCNC(=O)C1=NC=C(C=C1)OC2=C3C(=C(S2)C(=O)N)CCC4=C3SN=C4
    InChIKey
    NENJFZKQHYXRDQ-UHFFFAOYSA-N
    InChI
    1S/C19H18N4O4S2/c1-26-7-6-21-18(25)13-5-3-11(9-22-13)27-19-14-12(16(28-19)17(20)24)4-2-10-8-23-29-15(10)14/h3,5,8-9H,2,4,6-7H2,1H3,(H2,20,24)(H,21,25)
  11. BAY-985
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    BAY-985
    CAS: 2409479-29-2 Formula: C27H30F3N9O Molecular Weight: 553.58
    Moligand™ ? Moligand™ — Aladdin's line of ligands and bioactive small molecules. Use for receptor, pathway, and binding studies needing defined small-molecule tools. 10 mM in DMSO
    Out of Stock Item #: B1496245
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  12. BIIB068 - Moligand™, 10 mM in DMSO CAS No(1798787-27-5) by Aladdin Scientific
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    BIIB068
    CAS: 1798787-27-5 Formula: C23H29N7O2 Molecular Weight: 435.52
    Moligand™ ? Moligand™ — Aladdin's line of ligands and bioactive small molecules. Use for receptor, pathway, and binding studies needing defined small-molecule tools. 10 mM in DMSO
    Out of Stock Item #: B1496103
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