Phosphatidylinositol 4-phosphate 3-kinase c2 domain-containing subunit alpha (PIK3C2A)

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  1. SAR-405, Inhibitor of phosphatidylinositol 3-kinase catalytic subunit type 3
    CAS: 1523406-39-4 Formula: C19H21ClF3N5O2 Molecular Weight: 443.85
    Solid Moligand™ ? Moligand™ — Aladdin's line of ligands and bioactive small molecules. Use for receptor, pathway, and binding studies needing defined small-molecule tools. ≥97%
    Out of Stock Item #: S174388
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    IUPAC Name
    (8S)-9-[(5-chloropyridin-3-yl)methyl]-2-[(3R)-3-methylmorpholin-4-yl]-8-(trifluoromethyl)-7,8-dihydro-6H-pyrimido[1,2-a]pyrimidin-4-one
    SMILES
    CC1COCCN1C2=CC(=O)N3CCC(N(C3=N2)CC4=CC(=CN=C4)Cl)C(F)(F)F
    InChIKey
    SPDQRCUBFSRAFI-DOMZBBRYSA-N
    InChI
    1S/C19H21ClF3N5O2/c1-12-11-30-5-4-26(12)16-7-17(29)27-3-2-15(19(21,22)23)28(18(27)25-16)10-13-6-14(20)9-24-8-13/h6-9,12,15H,2-5,10-11H2,1H3/t12-,15+/mshow more
    Synonyms
    (S)-9-((5-Chloropyridin-3-yl)methyl)-2-((R)-3-methylmorpholino)-8-(trifluoromethyl)-6,7,8,9-tetrahydro-4H-pyrimido[1,...
  2. A66
    CAS: 1166227-08-2 PubChem CID: 42636535 Formula: C17H23N5O2S2 Molecular Weight: 393.53
    In Stock Item #: A128051
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    IUPAC Name
    (2S)-1-N-[5-(2-tert-butyl-1,3-thiazol-4-yl)-4-methyl-1,3-thiazol-2-yl]pyrrolidine-1,2-dicarboxamide
    SMILES
    CC1=C(SC(=N1)NC(=O)N2CCCC2C(=O)N)C3=CSC(=N3)C(C)(C)C
    InChIKey
    HBPXWEPKNBHKAX-NSHDSACASA-N
    InChI
    1S/C17H23N5O2S2/c1-9-12(10-8-25-14(20-10)17(2,3)4)26-15(19-9)21-16(24)22-7-5-6-11(22)13(18)23/h8,11H,5-7H2,1-4H3,(H2,18,23)(H,19,21,24)/t11-/m0/s1
    Synonyms
    AKOS025293511 | BDBM50042922 | CHEBI:91449 | C71541 | SMR004702785 | s2636 | SCHEMBL14833311 | A66, >=98% (HPLC) | BA...
  3. A66
    CAS: 1166227-08-2 PubChem CID: 42636535 Formula: C17H23N5O2S2 Molecular Weight: 393.53
    10mM in DMSO
    In Stock Item #: A408153
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    Synonyms
    (2S)-N1-(5-(2-tert-butylthiazol-4-yl)-4-methylthiazol-2-yl)pyrrolidine-1,2-dicarboxamide
  4. SAR405, Inhibitor of phosphatidylinositol 3-kinase catalytic subunit type 3
    CAS: 1523406-39-4 Formula: C19H21ClF3N5O2 Molecular Weight: 443.85
    Moligand™ ? Moligand™ — Aladdin's line of ligands and bioactive small molecules. Use for receptor, pathway, and binding studies needing defined small-molecule tools. 10mM in DMSO
    Out of Stock Item #: S408270
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    Synonyms
    4H-​Pyrimido[1,​2-​a]​pyrimidin-​4-​one, 9-​[(5-​chloro-​3-​pyridinyl)​methyl]​-​6,​7,​8,​9-​tetrahydro-​2-​[(3R)​-​3-...
  5. Torin 1, Inhibitor of mechanistic target of rapamycin kinase
    CAS: 1222998-36-8 PubChem CID: 49836027 Formula: C35H28F3N5O2 Molecular Weight: 607.62
    Moligand™ ? Moligand™ — Aladdin's line of ligands and bioactive small molecules. Use for receptor, pathway, and binding studies needing defined small-molecule tools. 2mM in DMSO
    In Stock Item #: T420960
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    IUPAC Name
    1-[4-(4-propanoylpiperazin-1-yl)-3-(trifluoromethyl)phenyl]-9-quinolin-3-ylbenzo[h][1,6]naphthyridin-2-one
    SMILES
    CCC(=O)N1CCN(CC1)C2=C(C=C(C=C2)N3C(=O)C=CC4=CN=C5C=CC(=CC5=C43)C6=CC7=CC=CC=C7N=C6)C(F)(F)F
    InChIKey
    AKCRNFFTGXBONI-UHFFFAOYSA-N
    InChI
    1S/C35H28F3N5O2/c1-2-32(44)42-15-13-41(14-16-42)31-11-9-26(19-28(31)35(36,37)38)43-33(45)12-8-24-20-40-30-10-7-22(18-27(30)34(24)43)25-17-23-5-3-4-6-2show more
    Synonyms
    BCP02504 | J-504118 | HMS3265P03 | Torin 1 is known as a selective mTOR inhibitor. | AS-55924 | s2827 | AC-31516 | CC...
  6. CNX-1351
    CAS: 1276105-89-5 PubChem CID: 58441401 Formula: C30H35N7O3S Molecular Weight: 573.71
    Solid Moligand™ ? Moligand™ — Aladdin's line of ligands and bioactive small molecules. Use for receptor, pathway, and binding studies needing defined small-molecule tools. ≥99%
    Out of Stock Item #: C647904
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    IUPAC Name
    1-[4-[[2-(1H-indazol-4-yl)-4-morpholin-4-ylthieno[3,2-d]pyrimidin-6-yl]methyl]piperazin-1-yl]-6-methylhept-5-ene-1,4-dione
    SMILES
    CC(=CC(=O)CCC(=O)N1CCN(CC1)CC2=CC3=C(S2)C(=NC(=N3)C4=C5C=NNC5=CC=C4)N6CCOCC6)C
    InChIKey
    DLNUPKDFXMWRFP-UHFFFAOYSA-N
    InChI
    1S/C30H35N7O3S/c1-20(2)16-21(38)6-7-27(39)36-10-8-35(9-11-36)19-22-17-26-28(41-22)30(37-12-14-40-15-13-37)33-29(32-26)23-4-3-5-25-24(23)18-31-34-25/h3show more
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