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Platelet-derived growth factor receptor beta (PDGFRB)

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  1. SU-5402
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    SU-5402
    CAS: 215543-92-3 Formula: C17H16N2O3 Molecular Weight: 296.32
    ≥98%
    In Stock Item #: S276590
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    Technical Identifiers
    IUPAC Name
    3-[4-methyl-2-[(Z)-(2-oxo-1H-indol-3-ylidene)methyl]-1H-pyrrol-3-yl]propanoic acid
    SMILES
    CC1=CNC(=C1CCC(=O)O)C=C2C3=CC=CC=C3NC2=O
    InChIKey
    JNDVEAXZWJIOKB-JYRVWZFOSA-N
    InChI
    1S/C17H16N2O3/c1-10-9-18-15(11(10)6-7-16(20)21)8-13-12-4-2-3-5-14(12)19-17(13)22/h2-5,8-9,18H,6-7H2,1H3,(H,19,22)(H,20,21)/b13-8-
    Synonyms
    HY-10407G | BCPP000060 | SCHEMBL177917 | SU 5402 | su5402 | SU-5402 | (Z)-3-(4-methyl-2-((2-oxoindolin-3-ylidene)meth...
  2. NVP-BHG712
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    NVP-BHG712
    CAS: 940310-85-0 EC Number: 804-395-8 Formula: C26H20F3N7O Molecular Weight: 503.48
    ≥98%
    In Stock Item #: N127928
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    Technical Identifiers
    IUPAC Name
    4-methyl-3-[(1-methyl-6-pyridin-3-ylpyrazolo[3,4-d]pyrimidin-4-yl)amino]-N-[3-(trifluoromethyl)phenyl]benzamide
    SMILES
    CC1=C(C=C(C=C1)C(=O)NC2=CC=CC(=C2)C(F)(F)F)NC3=C4C=NN(C4=NC(=N3)C5=CN=CC=C5)C
    InChIKey
    ZCCPLJOKGAACRT-UHFFFAOYSA-N
    InChI
    1S/C26H20F3N7O/c1-15-8-9-16(25(37)32-19-7-3-6-18(12-19)26(27,28)29)11-21(15)33-23-20-14-31-36(2)24(20)35-22(34-23)17-5-4-10-30-13-17/h3-14H,1-2H3,(H,3show more
    Synonyms
    4-Methyl-3-(1-methyl-6-pyridin-3-yl-1H-pyrazolo[3,4-d]pyrimidin-4-ylamino)-N-(3-trifluoromethyl-phenyl)-benzamide | B...
  3. RAF265 (CHIR-265), Vascular endothelial growth factor receptor 2 inhibitor
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    RAF265 (CHIR-265), Vascular endothelial growth factor receptor 2 inhibitor
    CAS: 927880-90-8 PubChem CID: 11656518 Formula: C24H16F6N6O Molecular Weight: 518.43
    Moligand™ ? Moligand™ — Aladdin's line of ligands and bioactive small molecules. Use for receptor, pathway, and binding studies needing defined small-molecule tools. ≥98%
    In Stock Item #: R127906
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    IUPAC Name
    1-methyl-5-[2-[5-(trifluoromethyl)-1H-imidazol-2-yl]pyridin-4-yl]oxy-N-[4-(trifluoromethyl)phenyl]benzimidazol-2-amine
    SMILES
    CN1C2=C(C=C(C=C2)OC3=CC(=NC=C3)C4=NC=C(N4)C(F)(F)F)N=C1NC5=CC=C(C=C5)C(F)(F)F
    InChIKey
    YABJJWZLRMPFSI-UHFFFAOYSA-N
    InChI
    1S/C24H16F6N6O/c1-36-19-7-6-15(10-17(19)34-22(36)33-14-4-2-13(3-5-14)23(25,26)27)37-16-8-9-31-18(11-16)21-32-12-20(35-21)24(28,29)30/h2-12H,1H3,(H,32,show more
    Synonyms
    CHIR265 | CHIR-265 | FT-0746327 | HMS3672I21 | NCGC00015003-02 | 1-methyl-5-[2-(5-trifluoromethyl-1H-imidazol-2-yl)py...
  4. Regorafenib (BAY 73-4506), Nerve growth factor receptor Trk-A
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    Regorafenib (BAY 73-4506), Nerve growth factor receptor Trk-A
    CAS: 755037-03-7 EC Number: 815-051-1 PubChem CID: 11167602 Formula: C21H15ClF4N4O3 Molecular Weight: 482.82
    Moligand™ ? Moligand™ — Aladdin's line of ligands and bioactive small molecules. Use for receptor, pathway, and binding studies needing defined small-molecule tools. ≥99%
    In Stock Item #: R127804
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    IUPAC Name
    4-[4-[[4-chloro-3-(trifluoromethyl)phenyl]carbamoylamino]-3-fluorophenoxy]-N-methylpyridine-2-carboxamide
    SMILES
    CNC(=O)C1=NC=CC(=C1)OC2=CC(=C(C=C2)NC(=O)NC3=CC(=C(C=C3)Cl)C(F)(F)F)F
    InChIKey
    FNHKPVJBJVTLMP-UHFFFAOYSA-N
    InChI
    1S/C21H15ClF4N4O3/c1-27-19(31)18-10-13(6-7-28-18)33-12-3-5-17(16(23)9-12)30-20(32)29-11-2-4-15(22)14(8-11)21(24,25)26/h2-10H,1H3,(H,27,31)(H2,29,30,32show more
    Synonyms
    CCG-269571 | AB00076187-01 | CHEBI:68647 | 755037-03-7 , Regorafenib | AC-25075 | MFCD16038047 | Regorafenib,BAY 73-4...
  5. SU 16f - ≥98%(HPLC) CAS No(251356-45-3) by Aladdin Scientific
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    SU 16f
    CAS: 251356-45-3 PubChem CID: 5329150 Formula: C24H22N2O3 Molecular Weight: 386.44
    Solid ≥98%(HPLC)
    In Stock Item #: S288019
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    IUPAC Name
    3-[2,4-dimethyl-5-[(Z)-(2-oxo-6-phenyl-1H-indol-3-ylidene)methyl]-1H-pyrrol-3-yl]propanoic acid
    SMILES
    CC1=C(NC(=C1CCC(=O)O)C)C=C2C3=C(C=C(C=C3)C4=CC=CC=C4)NC2=O
    InChIKey
    APYYTEJNOZQZNA-MOSHPQCFSA-N
    InChI
    1S/C24H22N2O3/c1-14-18(10-11-23(27)28)15(2)25-21(14)13-20-19-9-8-17(12-22(19)26-24(20)29)16-6-4-3-5-7-16/h3-9,12-13,25H,10-11H2,1-2H3,(H,26,29)(H,27,2show more
    Synonyms
    (Z)-3-(2,4-Dimethyl-5-(2-oxo-1,2-dihydro-indol-3-ylidenemethyl-6-phenyl)-1H-pyrrol-3-yl)-propionic acid | VEGFR Tyros...
  6. PF-04217903, Hepatocyte growth factor receptor inhibitor
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    PF-04217903, Hepatocyte growth factor receptor inhibitor
    CAS: 956905-27-4 Formula: C19H16N8O Molecular Weight: 372.38
    ≥98%
    In Stock Item #: P127567
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    IUPAC Name
    2-[4-[3-(quinolin-6-ylmethyl)triazolo[4,5-b]pyrazin-5-yl]pyrazol-1-yl]ethanol
    SMILES
    C1=CC2=C(C=CC(=C2)CN3C4=NC(=CN=C4N=N3)C5=CN(N=C5)CCO)N=C1
    InChIKey
    PDMUGYOXRHVNMO-UHFFFAOYSA-N
    InChI
    1S/C19H16N8O/c28-7-6-26-12-15(9-22-26)17-10-21-18-19(23-17)27(25-24-18)11-13-3-4-16-14(8-13)2-1-5-20-16/h1-5,8-10,12,28H,6-7,11H2
    Synonyms
    2-(4-(3-(quinolin-6-ylmethyl)-3H-[1,2,3]triazolo[4,5-b]pyrazin-5-yl)-1H-pyrazol-1-yl)ethanol | 2-[4-[1-(Quinolin-6-yl...
  7. JNJ-10198409
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    JNJ-10198409
    CAS: 627512-69-0 Formula: C18H16FN3O2 Molecular Weight: 325.34
    ≥98%
    Out of Stock Item #: J276446
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    Technical Identifiers
    IUPAC Name
    N-(3-fluorophenyl)-6,7-dimethoxy-1,4-dihydroindeno[1,2-c]pyrazol-3-amine
    SMILES
    COC1=C(C=C2C(=C1)CC3=C2NN=C3NC4=CC(=CC=C4)F)OC
    InChIKey
    ZDNURMVOKAERHZ-UHFFFAOYSA-N
    InChI
    1S/C18H16FN3O2/c1-23-15-7-10-6-14-17(13(10)9-16(15)24-2)21-22-18(14)20-12-5-3-4-11(19)8-12/h3-5,7-9H,6H2,1-2H3,(H2,20,21,22)
    Synonyms
    JNJ 10198409 | HMS3650O03 | DTXSID70430890 | CAB51840 | HMS3229I11 | HMS3674K21 | BDBM50179207 | SR-01000946814-1 | N...
  8. AG 1295
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    AG 1295
    CAS: 71897-07-9 Formula: C16H14N2 Molecular Weight: 234.30
    Moligand™ ? Moligand™ — Aladdin's line of ligands and bioactive small molecules. Use for receptor, pathway, and binding studies needing defined small-molecule tools. ≥98%
    In Stock Item #: T275676
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    IUPAC Name
    6,7-dimethyl-2-phenylquinoxaline
    SMILES
    CC1=CC2=NC=C(N=C2C=C1C)C3=CC=CC=C3
    InChIKey
    FQNCLVJEQCJWSU-UHFFFAOYSA-N
    InChI
    1S/C16H14N2/c1-11-8-14-15(9-12(11)2)18-16(10-17-14)13-6-4-3-5-7-13/h3-10H,1-2H3
    Synonyms
    6,7-Dimethyl-2-phenylquinoxaline
  9. Vatalanib succinate
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    Vatalanib succinate
    CAS: 212142-18-2 EC Number: 658-085-0 PubChem CID: 151193 Formula: C20H15ClN4•C4H6O4 Molecular Weight: 464.90
    ≥99%(HPLC)
    In Stock Item #: V286725
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    IUPAC Name
    butanedioic acid;N-(4-chlorophenyl)-4-(pyridin-4-ylmethyl)phthalazin-1-amine
    SMILES
    C1=CC=C2C(=C1)C(=NN=C2NC3=CC=C(C=C3)Cl)CC4=CC=NC=C4.C(CC(=O)O)C(=O)O
    InChIKey
    LLDWLPRYLVPDTG-UHFFFAOYSA-N
    InChI
    1S/C20H15ClN4.C4H6O4/c21-15-5-7-16(8-6-15)23-20-18-4-2-1-3-17(18)19(24-25-20)13-14-9-11-22-12-10-14;5-3(6)1-2-4(7)8/h1-12H,13H2,(H,23,25);1-2H2,(H,5,6show more
    Synonyms
    1-(4-chloroanilino)-4-(4-pyridylmethyl)phthalazine succinate | PTK 787/ZK 222584 | 1-Phthalazinamine, N-(4-chlorophen...
  10. Pazopanib, Inhibitor of colony stimulating factor 1 receptor;Inhibitor of fibroblast growth factor receptor 1;Inhibitor of fms related receptor tyrosine kinase 1;Inhibitor of fms related receptor tyrosine kinase 4;Inhibitor of kinase insert domain receptor;Inhibitor
    Wish List Compare
    Pazopanib, Inhibitor of colony stimulating factor 1 receptor;Inhibitor of fibroblast growth factor receptor 1;Inhibitor of fms related receptor tyrosine kinase 1;Inhibitor of fms related receptor tyrosine kinase 4;Inhibitor of kinase insert domain receptor;Inhibitor
    CAS: 444731-52-6 EC Number: 963-764-2 Formula: C21H23N7O2S Molecular Weight: 437.53
    Moligand™ ? Moligand™ — Aladdin's line of ligands and bioactive small molecules. Use for receptor, pathway, and binding studies needing defined small-molecule tools. ≥99%
    In Stock Item #: P125184
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    IUPAC Name
    5-[[4-[(2,3-dimethylindazol-6-yl)-methylamino]pyrimidin-2-yl]amino]-2-methylbenzenesulfonamide
    SMILES
    CC1=C(C=C(C=C1)NC2=NC=CC(=N2)N(C)C3=CC4=NN(C(=C4C=C3)C)C)S(=O)(=O)N
    InChIKey
    CUIHSIWYWATEQL-UHFFFAOYSA-N
    InChI
    1S/C21H23N7O2S/c1-13-5-6-15(11-19(13)31(22,29)30)24-21-23-10-9-20(25-21)27(3)16-7-8-17-14(2)28(4)26-18(17)12-16/h5-12H,1-4H3,(H2,22,29,30)(H,23,24,25)
    Synonyms
    5-[[4-[(2,3-Dimethyl-2H-indazol-6-yl)(methyl)amino]-pyrimidin-2-yl]amino]-2-methyl-benzenesulfonamide | 5-[[4-[(2,3-d...
  11. Linifanib (ABT-869), Vascular endothelial growth factor receptor inhibitor
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    Linifanib (ABT-869), Vascular endothelial growth factor receptor inhibitor
    CAS: 796967-16-3 EC Number: 681-638-2 Formula: C21H18FN5O Molecular Weight: 375.41
    Moligand™ ? Moligand™ — Aladdin's line of ligands and bioactive small molecules. Use for receptor, pathway, and binding studies needing defined small-molecule tools. ≥99%
    In Stock Item #: L126993
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    IUPAC Name
    1-[4-(3-amino-1H-indazol-4-yl)phenyl]-3-(2-fluoro-5-methylphenyl)urea
    SMILES
    CC1=CC(=C(C=C1)F)NC(=O)NC2=CC=C(C=C2)C3=C4C(=CC=C3)NN=C4N
    InChIKey
    MPVGZUGXCQEXTM-UHFFFAOYSA-N
    InChI
    1S/C21H18FN5O/c1-12-5-10-16(22)18(11-12)25-21(28)24-14-8-6-13(7-9-14)15-3-2-4-17-19(15)20(23)27-26-17/h2-11H,1H3,(H3,23,26,27)(H2,24,25,28)
    Synonyms
    A19393 | D09635 | A-741439 | FT-0696226 | LINIFANIB [INN] | NSC764237 | NSC-764237 | CCG-264767 | J-503186 | Linifani...
  12. Masitinib (AB1010), Platelet-derived growth factor receptor inhibitor
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    Masitinib (AB1010), Platelet-derived growth factor receptor inhibitor
    CAS: 790299-79-5 Formula: C28H30N6OS Molecular Weight: 498.65
    Moligand™ ? Moligand™ — Aladdin's line of ligands and bioactive small molecules. Use for receptor, pathway, and binding studies needing defined small-molecule tools. ≥98%
    In Stock Item #: M126981
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    IUPAC Name
    4-[(4-methylpiperazin-1-yl)methyl]-N-[4-methyl-3-[(4-pyridin-3-yl-1,3-thiazol-2-yl)amino]phenyl]benzamide
    SMILES
    CC1=C(C=C(C=C1)NC(=O)C2=CC=C(C=C2)CN3CCN(CC3)C)NC4=NC(=CS4)C5=CN=CC=C5
    InChIKey
    WJEOLQLKVOPQFV-UHFFFAOYSA-N
    InChI
    1S/C28H30N6OS/c1-20-5-10-24(16-25(20)31-28-32-26(19-36-28)23-4-3-11-29-17-23)30-27(35)22-8-6-21(7-9-22)18-34-14-12-33(2)13-15-34/h3-11,16-17,19H,12-15show more
    Synonyms
    4-((4-METHYLPIPERAZIN-1-YL)METHYL)-N-(4-METHYL-3-((4-PYRIDIN-3-YL-1,3-THIAZOL-2-YL)AMINO)PHENYL)BENZAMIDE | Masitinib...
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