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Serine/threonine-protein kinase chk2 (CHEK2)

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  1. 6-(Dimethylamino)purine
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    6-(Dimethylamino)purine
    CAS: 938-55-6 EC Number: 213-344-3 Formula: C7H9N5 Molecular Weight: 163.18
    ≥97%(HPLC)
    In Stock Item #: D131565
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    Technical Identifiers
    IUPAC Name
    N,N-dimethyl-7H-purin-6-amine
    SMILES
    CN(C)C1=NC=NC2=C1NC=N2
    InChIKey
    BVIAOQMSVZHOJM-UHFFFAOYSA-N
    InChI
    1S/C7H9N5/c1-12(2)7-5-6(9-3-8-5)10-4-11-7/h3-4H,1-2H3,(H,8,9,10,11)
    Synonyms
    6-DMAP | N6 | Dimethyl-(9H-purin-6-yl)-amine | AKOS015850812 | 9H-PURIN-6-AMINE, N,N-DIMETHYL- | 6-DMAP | AKOS0281091...
  2. TSU-68 (SU6668, Orantinib), Inhibitor of epidermal growth factor receptor;Inhibitor of fibroblast growth factor receptor 1;Inhibitor of kinase insert domain receptor;Inhibitor of platelet derived growth factor receptor beta
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    TSU-68 (SU6668, Orantinib), Inhibitor of epidermal growth factor receptor;Inhibitor of fibroblast growth factor receptor 1;Inhibitor of kinase insert domain receptor;Inhibitor of platelet derived growth factor receptor beta
    CAS: 252916-29-3 PubChem CID: 5329099 Formula: C18H18N2O3 Molecular Weight: 310.35
    Moligand™ ? Moligand™ — Aladdin's line of ligands and bioactive small molecules. Use for receptor, pathway, and binding studies needing defined small-molecule tools. ≥98%
    In Stock Item #: T125079
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    Technical Identifiers
    IUPAC Name
    3-[2,4-dimethyl-5-[(Z)-(2-oxo-1H-indol-3-ylidene)methyl]-1H-pyrrol-3-yl]propanoic acid
    SMILES
    CC1=C(NC(=C1CCC(=O)O)C)C=C2C3=CC=CC=C3NC2=O
    InChIKey
    NHFDRBXTEDBWCZ-ZROIWOOFSA-N
    InChI
    1S/C18H18N2O3/c1-10-12(7-8-17(21)22)11(2)19-16(10)9-14-13-5-3-4-6-15(13)20-18(14)23/h3-6,9,19H,7-8H2,1-2H3,(H,20,23)(H,21,22)/b14-9-
    Synonyms
    3-{2,4-Dimethyl-5-[(Z)-(2-Oxo-1,2-Dihydro-3h-Indol-3-Ylidene)methyl]-1h-Pyrrol-3-Yl}propanoic Acid | J-502593 | ORANT...
  3. 6-(Dimethylamino)purine
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    6-(Dimethylamino)purine
    CAS: 938-55-6 EC Number: 213-344-3 Formula: C7H9N5 Molecular Weight: 163.18
    10mM in DMSO
    In Stock Item #: D426998
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    Technical Identifiers
    IUPAC Name
    N,N-dimethyl-7H-purin-6-amine
    SMILES
    CN(C)C1=NC=NC2=C1NC=N2
    InChIKey
    BVIAOQMSVZHOJM-UHFFFAOYSA-N
    InChI
    1S/C7H9N5/c1-12(2)7-5-6(9-3-8-5)10-4-11-7/h3-4H,1-2H3,(H,8,9,10,11)
    Synonyms
    6-DMAP | Dimethyl-(9H-purin-6-yl)-amine | AKOS015850812 | 9H-PURIN-6-AMINE, N,N-DIMETHYL- | 6-DMAP | AKOS028109175 | ...
  4. AZD7762, Serine/threonine-protein kinase Chk1 inhibitor
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    AZD7762, Serine/threonine-protein kinase Chk1 inhibitor
    CAS: 860352-01-8 EC Number: 804-400-3 Formula: C17H19FN4O2S Molecular Weight: 362.42
    Moligand™ ? Moligand™ — Aladdin's line of ligands and bioactive small molecules. Use for receptor, pathway, and binding studies needing defined small-molecule tools. 10mM in DMSO
    In Stock Item #: A408077
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    Synonyms
    1-(2-((S)-piperidin-3-ylcarbamoyl)-5-(3-fluorophenyl)thiophen-3-yl)urea
  5. AZD7762, Serine/threonine-protein kinase Chk1 inhibitor
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    AZD7762, Serine/threonine-protein kinase Chk1 inhibitor
    CAS: 860352-01-8 EC Number: 804-400-3 Formula: C17H19FN4O2S Molecular Weight: 362.42
    Moligand™ ? Moligand™ — Aladdin's line of ligands and bioactive small molecules. Use for receptor, pathway, and binding studies needing defined small-molecule tools. ≥98%
    In Stock Item #: A127862
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    Technical Identifiers
    IUPAC Name
    3-(carbamoylamino)-5-(3-fluorophenyl)-N-[(3S)-piperidin-3-yl]thiophene-2-carboxamide
    SMILES
    C1CC(CNC1)NC(=O)C2=C(C=C(S2)C3=CC(=CC=C3)F)NC(=O)N
    InChIKey
    IAYGCINLNONXHY-LBPRGKRZSA-N
    InChI
    1S/C17H19FN4O2S/c18-11-4-1-3-10(7-11)14-8-13(22-17(19)24)15(25-14)16(23)21-12-5-2-6-20-9-12/h1,3-4,7-8,12,20H,2,5-6,9H2,(H,21,23)(H3,19,22,24)/t12-/m0show more
    Synonyms
    5D822Y3L1H | H1206 | 4,4'-DIMETHOXYTHIOCARBANILIDE | BS-22319 | C17H19FN4O2S | CCG-264907 | J-502468 | AZD 7762 | BDB...
  6. CCT241533, Inhibitor of checkpoint kinase 1;Inhibitor of checkpoint kinase 2
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    CCT241533, Inhibitor of checkpoint kinase 1;Inhibitor of checkpoint kinase 2
    CAS: 1262849-73-9 Formula: C23H27FN4O4 Molecular Weight: 442.48
    Moligand™ ? Moligand™ — Aladdin's line of ligands and bioactive small molecules. Use for receptor, pathway, and binding studies needing defined small-molecule tools.
    Out of Stock Item #: C125629
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    IUPAC Name
    4-fluoro-2-[4-[[(3S,4R)-4-(2-hydroxypropan-2-yl)pyrrolidin-3-yl]amino]-6,7-dimethoxyquinazolin-2-yl]phenol
    SMILES
    CC(C)(C1CNCC1NC2=NC(=NC3=CC(=C(C=C32)OC)OC)C4=C(C=CC(=C4)F)O)O
    InChIKey
    HZASIAXCPXTISQ-NVXWUHKLSA-N
    InChI
    1S/C23H27FN4O4/c1-23(2,30)15-10-25-11-17(15)27-21-13-8-19(31-3)20(32-4)9-16(13)26-22(28-21)14-7-12(24)5-6-18(14)29/h5-9,15,17,25,29-30H,10-11H2,1-4H3,show more
    Synonyms
    A922008 | 4-fluoro-2-[4-[[(3S,4R)-4-(2-hydroxypropan-2-yl)pyrrolidin-3-yl]amino]-6,7-dimethoxyquinazolin-2-yl]phenol ...
  7. Chk2 inhibitor
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    Chk2 inhibitor
    CAS: 724708-21-8 Formula: C15H15N5O2 Molecular Weight: 295.3
    ≥95%
    Out of Stock Item #: C337162
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    IUPAC Name
    5-(2-amino-4-hydroxy-1H-imidazol-5-yl)-3,4-dihydro-2H-azepino[3,4-b]indol-1-one
    SMILES
    C1CNC(=O)C2=NC3=CC=CC=C3C2=C1C4=C(N=C(N4)N)O
    InChIKey
    RZEPRPGFGRQXDI-UHFFFAOYSA-N
    InChI
    1S/C15H13N5O2/c16-15-19-11(14(22)20-15)8-5-6-17-13(21)12-10(8)7-3-1-2-4-9(7)18-12/h1-4,22H,5-6H2,(H,17,21)(H3,16,19,20)
    Synonyms
    5-(2-Amino-5-oxo-1,5-dihydroimidazol-4-ylidine)-3,4,5,10-2H-azepino[3,4-b]indol-1-one
  8. Chk2 inhibitor II, Inhibitor of checkpoint kinase 2
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    Chk2 inhibitor II, Inhibitor of checkpoint kinase 2
    CAS: 516480-79-8 Formula: C20H14CIN3O2 Molecular Weight: 363.8
    Moligand™ ? Moligand™ — Aladdin's line of ligands and bioactive small molecules. Use for receptor, pathway, and binding studies needing defined small-molecule tools. ≥98%
    In Stock Item #: C275315
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    Technical Identifiers
    IUPAC Name
    2-[4-(4-chlorophenoxy)phenyl]-3H-benzimidazole-5-carboxamide
    SMILES
    C1=CC(=CC=C1C2=NC3=C(N2)C=C(C=C3)C(=O)N)OC4=CC=C(C=C4)Cl
    InChIKey
    UXGJAOIJSROTTN-UHFFFAOYSA-N
    InChI
    1S/C20H14ClN3O2/c21-14-4-8-16(9-5-14)26-15-6-1-12(2-7-15)20-23-17-10-3-13(19(22)25)11-18(17)24-20/h1-11H,(H2,22,25)(H,23,24)
    Synonyms
    Regadenoson; CVT-3146 | Chk2 Inhibitor II | BML277 | BML-277 | HMS3745A07 | NCGC00165768-02 | NSC741899 | NSC-741899 ...
  9. Chk2 inhibitor II, Inhibitor of checkpoint kinase 2
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    Chk2 inhibitor II, Inhibitor of checkpoint kinase 2
    CAS: 516480-79-8 Formula: C20H14CIN3O2 Molecular Weight: 363.8
    Moligand™ ? Moligand™ — Aladdin's line of ligands and bioactive small molecules. Use for receptor, pathway, and binding studies needing defined small-molecule tools. 10mM in DMSO
    In Stock Item #: C424436
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    Technical Identifiers
    IUPAC Name
    2-[4-(4-chlorophenoxy)phenyl]-3H-benzimidazole-5-carboxamide
    SMILES
    C1=CC(=CC=C1C2=NC3=C(N2)C=C(C=C3)C(=O)N)OC4=CC=C(C=C4)Cl
    InChIKey
    UXGJAOIJSROTTN-UHFFFAOYSA-N
    InChI
    1S/C20H14ClN3O2/c21-14-4-8-16(9-5-14)26-15-6-1-12(2-7-15)20-23-17-10-3-13(19(22)25)11-18(17)24-20/h1-11H,(H2,22,25)(H,23,24)
    Synonyms
    Regadenoson; CVT-3146 | Chk2 Inhibitor II | BML277 | BML-277 | HMS3745A07 | NCGC00165768-02 | NSC741899 | NSC-741899 ...
  10. Orantinib (SU6668), Inhibitor of epidermal growth factor receptor;Inhibitor of fibroblast growth factor receptor 1;Inhibitor of kinase insert domain receptor;Inhibitor of platelet derived growth factor receptor beta
    Wish List Compare
    Orantinib (SU6668), Inhibitor of epidermal growth factor receptor;Inhibitor of fibroblast growth factor receptor 1;Inhibitor of kinase insert domain receptor;Inhibitor of platelet derived growth factor receptor beta
    CAS: 252916-29-3 PubChem CID: 5329099 Formula: C18H18N2O3 Molecular Weight: 310.35
    Moligand™ ? Moligand™ — Aladdin's line of ligands and bioactive small molecules. Use for receptor, pathway, and binding studies needing defined small-molecule tools. 10mM in DMSO
    In Stock Item #: O407925
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    Technical Identifiers
    Synonyms
    TSU-68 | (Z)-3-(2,4-dimethyl-5-((2-oxoindolin-3-ylidene)methyl)-1H-pyrrol-3-yl)propanoic acid
  11. SAR-020106
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    SAR-020106
    CAS: 1184843-57-9 PubChem CID: 44203948 Formula: C19H19ClN6O Molecular Weight: 382.85
    10mM in DMSO
    In Stock Item #: S420813
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    Technical Identifiers
    IUPAC Name
    5-[(8-chloroisoquinolin-3-yl)amino]-3-[(2R)-1-(dimethylamino)propan-2-yl]oxypyrazine-2-carbonitrile
    SMILES
    CC(CN(C)C)OC1=NC(=CN=C1C#N)NC2=NC=C3C(=C2)C=CC=C3Cl
    InChIKey
    SRBJWIBAMIKCMV-GFCCVEGCSA-N
    InChI
    1S/C19H19ClN6O/c1-12(11-26(2)3)27-19-16(8-21)22-10-18(25-19)24-17-7-13-5-4-6-15(20)14(13)9-23-17/h4-7,9-10,12H,11H2,1-3H3,(H,23,24,25)/t12-/m1/s1
    Synonyms
    5-[(8-Chloro-3-isoquinolinyl)amino]-3-[(1R)-2-(dimethylamino)-1-methylethoxy]-2-pyrazinecarbonitrile
  12. SAR-020106 - ≥97% CAS No(1184843-57-9) by Aladdin Scientific
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    SAR-020106
    CAS: 1184843-57-9 PubChem CID: 44203948 Formula: C19H19ClN6O Molecular Weight: 382.85
    ≥97%
    In Stock Item #: S413824
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    Pricing & Pack Sizes
    Technical Identifiers
    IUPAC Name
    5-[(8-chloroisoquinolin-3-yl)amino]-3-[(2R)-1-(dimethylamino)propan-2-yl]oxypyrazine-2-carbonitrile
    SMILES
    CC(CN(C)C)OC1=NC(=CN=C1C#N)NC2=NC=C3C(=C2)C=CC=C3Cl
    InChIKey
    SRBJWIBAMIKCMV-GFCCVEGCSA-N
    InChI
    1S/C19H19ClN6O/c1-12(11-26(2)3)27-19-16(8-21)22-10-18(25-19)24-17-7-13-5-4-6-15(20)14(13)9-23-17/h4-7,9-10,12H,11H2,1-3H3,(H,23,24,25)/t12-/m1/s1
    Synonyms
    5-[(8-Chloro-3-isoquinolinyl)amino]-3-[(1R)-2-(dimethylamino)-1-methylethoxy]-2-pyrazinecarbonitrile
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