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Serine/threonine-protein kinase n2 (PKN2)

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  1. GSK 269962, Inhibitor of Rho associated coiled-coil containing protein kinase 1;Inhibitor of Rho associated coiled-coil containing protein kinase 2
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    GSK 269962, Inhibitor of Rho associated coiled-coil containing protein kinase 1;Inhibitor of Rho associated coiled-coil containing protein kinase 2
    CAS: 850664-21-0 Formula: C29H30N8O5 Molecular Weight: 570.6
    Moligand™ ? Moligand™ — Aladdin's line of ligands and bioactive small molecules. Use for receptor, pathway, and binding studies needing defined small-molecule tools. ≥98%
    In Stock Item #: G287476
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    Technical Identifiers
    IUPAC Name
    N-[3-[2-(4-amino-1,2,5-oxadiazol-3-yl)-1-ethylimidazo[4,5-c]pyridin-6-yl]oxyphenyl]-4-(2-morpholin-4-ylethoxy)benzamide
    SMILES
    CCN1C2=CC(=NC=C2N=C1C3=NON=C3N)OC4=CC=CC(=C4)NC(=O)C5=CC=C(C=C5)OCCN6CCOCC6
    InChIKey
    YOVNFNXUCOWYSG-UHFFFAOYSA-N
    InChI
    1S/C29H30N8O5/c1-2-37-24-17-25(31-18-23(24)33-28(37)26-27(30)35-42-34-26)41-22-5-3-4-20(16-22)32-29(38)19-6-8-21(9-7-19)40-15-12-36-10-13-39-14-11-36/show more
    Synonyms
    GTPL8037 | NSC-767348 | SCHEMBL1838346 | UNII-F89KMM7TE2 | N-(3-((2-(4-Amino-1,2,5-oxadiazol-3-yl)-1-ethyl-1H-imidazo...
  2. PHA-767491, Inhibitor of MAPK activated protein kinase 2;Inhibitor of ribosomal protein S6 kinase A4
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    PHA-767491, Inhibitor of MAPK activated protein kinase 2;Inhibitor of ribosomal protein S6 kinase A4
    CAS: 845714-00-3 Formula: C12H11N3O Molecular Weight: 213.24
    Moligand™ ? Moligand™ — Aladdin's line of ligands and bioactive small molecules. Use for receptor, pathway, and binding studies needing defined small-molecule tools. ≥98%
    In Stock Item #: P127009
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    IUPAC Name
    2-pyridin-4-yl-1,5,6,7-tetrahydropyrrolo[3,2-c]pyridin-4-one
    SMILES
    C1CNC(=O)C2=C1NC(=C2)C3=CC=NC=C3
    InChIKey
    DKXHSOUZPMHNIZ-UHFFFAOYSA-N
    InChI
    1S/C12H11N3O/c16-12-9-7-11(8-1-4-13-5-2-8)15-10(9)3-6-14-12/h1-2,4-5,7,15H,3,6H2,(H,14,16)
    Synonyms
    2-(4-pyridyl)-1,5,6,7-tetrahydropyrrolo[3,2-c]pyridin-4-one | BDBM27344 | SMR004702829 | CAY10572(PHA-767491) | CHEBI...
  3. Y-33075, Rho-associated protein kinase inhibitor
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    Y-33075, Rho-associated protein kinase inhibitor
    CAS: 199433-58-4 PubChem CID: 9810884 Formula: C16H16N4O Molecular Weight: 280.33
    ≥98%
    Out of Stock Item #: Y125409
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    IUPAC Name
    4-[(1R)-1-aminoethyl]-N-(1H-pyrrolo[2,3-b]pyridin-4-yl)benzamide
    SMILES
    CC(C1=CC=C(C=C1)C(=O)NC2=C3C=CNC3=NC=C2)N
    InChIKey
    JTVBXQAYBIJXRP-SNVBAGLBSA-N
    InChI
    1S/C16H16N4O/c1-10(17)11-2-4-12(5-3-11)16(21)20-14-7-9-19-15-13(14)6-8-18-15/h2-10H,17H2,1H3,(H2,18,19,20,21)/t10-/m1/s1
    Synonyms
    CHEMBL571948|(R)-4-(1-aminoethyl)-N-(1H-pyrrolo[2,3-b]pyridin-4-yl)benzamide
  4. Hydroxyfasudil
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    Hydroxyfasudil
    CAS: 105628-72-6 Formula: C14H17N3O3S Molecular Weight: 307.37
    ≥98%
    In Stock Item #: H127222
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    Technical Identifiers
    IUPAC Name
    5-(1,4-diazepan-1-ylsulfonyl)-2H-isoquinolin-1-one
    SMILES
    C1CNCCN(C1)S(=O)(=O)C2=CC=CC3=C2C=CNC3=O
    InChIKey
    ZAVGJDAFCZAWSZ-UHFFFAOYSA-N
    InChI
    1S/C14H17N3O3S/c18-14-12-3-1-4-13(11(12)5-7-16-14)21(19,20)17-9-2-6-15-8-10-17/h1,3-5,7,15H,2,6,8-10H2,(H,16,18)
    Synonyms
    BRD-K77793136-003-02-2 | SY345499 | EYH4AU7P63 | AC-36853 | SCHEMBL123699 | Q27095449 | Hydroxyfasudil; HA-1100 | MFC...
  5. 2-(4-Pyridyl)benzimidazole
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    2-(4-Pyridyl)benzimidazole
    CAS: 2208-59-5 EC Number: 678-451-3 PubChem CID: 247634 Formula: C12H9N3 Molecular Weight: 195.23
    ≥96%(HPLC)
    In Stock Item #: P160620
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    IUPAC Name
    2-pyridin-4-yl-1H-benzimidazole
    SMILES
    C1=CC=C2C(=C1)NC(=N2)C3=CC=NC=C3
    InChIKey
    UYWWLYCGNNCLKE-UHFFFAOYSA-N
    InChI
    1S/C12H9N3/c1-2-4-11-10(3-1)14-12(15-11)9-5-7-13-8-6-9/h1-8H,(H,14,15)
    Synonyms
    Z50129789 | BDBM55759 | SMR000282981 | 2-(4-Pyridinyl)-1H-benzimidazole | 2-(Pyridin-4(1H)-ylidene)-2H-benzo[d]imidaz...
  6. AT13148, MAP kinase-activated protein kinase 2 inhibitor
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    AT13148, MAP kinase-activated protein kinase 2 inhibitor
    CAS: 1056901-62-2 Formula: C17H16ClN3O Molecular Weight: 313.78
    ≥98%
    In Stock Item #: A413783
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    Technical Identifiers
    IUPAC Name
    (1S)-2-amino-1-(4-chlorophenyl)-1-[4-(1H-pyrazol-4-yl)phenyl]ethanol
    SMILES
    C1=CC(=CC=C1C2=CNN=C2)C(CN)(C3=CC=C(C=C3)Cl)O
    InChIKey
    IIRWNGPLJQXWFJ-KRWDZBQOSA-N
    InChI
    1S/C17H16ClN3O/c18-16-7-5-15(6-8-16)17(22,11-19)14-3-1-12(2-4-14)13-9-20-21-10-13/h1-10,22H,11,19H2,(H,20,21)/t17-/m0/s1
    Synonyms
    (S)-1-(4-(1H-Pyrazol-4-yl)phenyl)-2-amino-1-(4-chlorophenyl)ethanol; SCHEMBL851471 | NCGC00386423-03 | SCHEMBL851471 ...
  7. AT13148, MAP kinase-activated protein kinase 2 inhibitor
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    AT13148, MAP kinase-activated protein kinase 2 inhibitor
    CAS: 1056901-62-2 Formula: C17H16ClN3O Molecular Weight: 313.78
    10mM in DMSO
    In Stock Item #: A420481
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    Technical Identifiers
    IUPAC Name
    (1S)-2-amino-1-(4-chlorophenyl)-1-[4-(1H-pyrazol-4-yl)phenyl]ethanol
    SMILES
    C1=CC(=CC=C1C2=CNN=C2)C(CN)(C3=CC=C(C=C3)Cl)O
    InChIKey
    IIRWNGPLJQXWFJ-KRWDZBQOSA-N
    InChI
    1S/C17H16ClN3O/c18-16-7-5-15(6-8-16)17(22,11-19)14-3-1-12(2-4-14)13-9-20-21-10-13/h1-10,22H,11,19H2,(H,20,21)/t17-/m0/s1
    Synonyms
    (S)-1-(4-(1H-Pyrazol-4-yl)phenyl)-2-amino-1-(4-chlorophenyl)ethanol; SCHEMBL851471 | NCGC00386423-03 | SCHEMBL851471 ...
  8. GSK 269962, Inhibitor of Rho associated coiled-coil containing protein kinase 1;Inhibitor of Rho associated coiled-coil containing protein kinase 2
    Wish List Compare
    GSK 269962, Inhibitor of Rho associated coiled-coil containing protein kinase 1;Inhibitor of Rho associated coiled-coil containing protein kinase 2
    CAS: 850664-21-0 Formula: C29H30N8O5 Molecular Weight: 570.6
    Moligand™ ? Moligand™ — Aladdin's line of ligands and bioactive small molecules. Use for receptor, pathway, and binding studies needing defined small-molecule tools. 10mM in DMSO
    In Stock Item #: G426254
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    Technical Identifiers
    IUPAC Name
    N-[3-[2-(4-amino-1,2,5-oxadiazol-3-yl)-1-ethylimidazo[4,5-c]pyridin-6-yl]oxyphenyl]-4-(2-morpholin-4-ylethoxy)benzamide
    SMILES
    CCN1C2=CC(=NC=C2N=C1C3=NON=C3N)OC4=CC=CC(=C4)NC(=O)C5=CC=C(C=C5)OCCN6CCOCC6
    InChIKey
    YOVNFNXUCOWYSG-UHFFFAOYSA-N
    InChI
    1S/C29H30N8O5/c1-2-37-24-17-25(31-18-23(24)33-28(37)26-27(30)35-42-34-26)41-22-5-3-4-20(16-22)32-29(38)19-6-8-21(9-7-19)40-15-12-36-10-13-39-14-11-36/show more
    Synonyms
    GSK269962A|850664-21-0|GSK 269962|GSK-269962A|925213-63-4|GSK269962|GSK 269962A|N-[3-[2-(4-amino-1,2,5-oxadiazol-3-yl...
  9. no_selection
    Wish List Compare
    (3S,4R)-N-(7-chloro-1-oxo-1,2-dihydroisoquinolin-6-yl)-4-(4-chlorophenyl)pyrrolidine-3-carboxamide, Inhibitor of Protein kinase G (PKG) 2;Inhibitor of protein kinase N2;Inhibitor of Rho associated coiled-coil containing protein kinase 2
    Moligand™ ? Moligand™ — Aladdin's line of ligands and bioactive small molecules. Use for receptor, pathway, and binding studies needing defined small-molecule tools.
    Out of Stock Item #: S609112
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    Technical Identifiers
    IUPAC Name
    (3S,4R)-N-(7-chloro-1-oxo-1,2-dihydroisoquinolin-6-yl)-4-(4-chlorophenyl)pyrrolidine-3-carboxamide
    SMILES
    O=C([C@@H]1CNC[C@H]1c1ccc(cc1)Cl)Nc1cc2cc[nH]c(=O)c2cc1Cl
    InChIKey
    XBFAFSAUQFDEOK-JKSUJKDBSA-N
    InChI
    1S/C20H17Cl2N3O2/c21-13-3-1-11(2-4-13)15-9-23-10-16(15)20(27)25-18-7-12-5-6-24-19(26)14(12)8-17(18)22/h1-8,15-16,23H,9-10H2,(H,24,26)(H,25,27)/t15-,16show more
    Synonyms
    compound 32
  10. no_selection
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    N-(7-chloro-1-oxo-1,2-dihydroisoquinolin-6-yl)-2-(cyclopropylamino)-2-phenylacetamide, Inhibitor of NIMA related kinase 6;Inhibitor of NIMA related kinase 7;Inhibitor of Rho associated coiled-coil containing protein kinase 1;Inhibitor of Rho associated coiled-coil containing protein kinase 2
    Moligand™ ? Moligand™ — Aladdin's line of ligands and bioactive small molecules. Use for receptor, pathway, and binding studies needing defined small-molecule tools.
    Out of Stock Item #: N608956
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    Technical Identifiers
    IUPAC Name
    N-(7-chloro-1-oxo-1,2-dihydroisoquinolin-6-yl)-2-(cyclopropylamino)-2-phenylacetamide
    SMILES
    O=C(C(c1ccccc1)NC1CC1)Nc1cc2cc[nH]c(=O)c2cc1Cl
    InChIKey
    SKYALJGMRAGHEN-UHFFFAOYSA-N
    InChI
    1S/C20H18ClN3O2/c21-16-11-15-13(8-9-22-19(15)25)10-17(16)24-20(26)18(23-14-6-7-14)12-4-2-1-3-5-12/h1-5,8-11,14,18,23H,6-7H2,(H,22,25)(H,24,26)
    Synonyms
    compound 22
  11. no_selection
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    6-piperidin-4-yloxy-2H-isoquinolin-1-one, Inhibitor of Rho associated coiled-coil containing protein kinase 1;Inhibitor of Rho associated coiled-coil containing protein kinase 2
    Moligand™ ? Moligand™ — Aladdin's line of ligands and bioactive small molecules. Use for receptor, pathway, and binding studies needing defined small-molecule tools.
    Out of Stock Item #: P613413
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    Technical Identifiers
    IUPAC Name
    6-piperidin-4-yloxy-2H-isoquinolin-1-one
    SMILES
    O=c1[nH]ccc2c1ccc(c2)OC1CCNCC1
    InChIKey
    IPEXHQGMTHOKQV-UHFFFAOYSA-N
    InChI
    1S/C14H16N2O2/c17-14-13-2-1-12(9-10(13)3-8-16-14)18-11-4-6-15-7-5-11/h1-3,8-9,11,15H,4-7H2,(H,16,17)
    Synonyms
    AMMONIUM BISULFITE [INCI] | BCP20035 | 3B974D670O | C77162 | SCHEMBL8934240 | A903661 | UNII-3B974D670O | IPEXHQGMTHO...
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