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Serine/threonine-protein kinase pim-2 (PIM2)

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  1. SMI-4a
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    SMI-4a
    CAS: 438190-29-5 EC Number: 803-742-0 PubChem CID: 1361334 Formula: C11H6F3NO2S Molecular Weight: 273.23
    ≥98%
    In Stock Item #: T125988
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    Technical Identifiers
    IUPAC Name
    (5Z)-5-[[3-(trifluoromethyl)phenyl]methylidene]-1,3-thiazolidine-2,4-dione
    SMILES
    C1=CC(=CC(=C1)C(F)(F)F)C=C2C(=O)NC(=O)S2
    InChIKey
    NGJLOFCOEOHFKQ-YVMONPNESA-N
    InChI
    1S/C11H6F3NO2S/c12-11(13,14)7-3-1-2-6(4-7)5-8-9(16)15-10(17)18-8/h1-5H,(H,15,16,17)/b8-5-
    Synonyms
    5-(3-(Trifluoromethyl)benzylidene)thiazolidine-2,4-dione | 5-[[3-(trifluoromethyl)phenyl]methylene]-2,4-thiazolidined...
  2. TCS PIM-1 1
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    TCS PIM-1 1
    CAS: 491871-58-0 PubChem CID: 1235170 Formula: C18H11BrN2O2 Molecular Weight: 367.2
    ≥98%(HPLC)
    In Stock Item #: T288715
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    Technical Identifiers
    IUPAC Name
    6-(5-bromo-2-hydroxyphenyl)-2-oxo-4-phenyl-1H-pyridine-3-carbonitrile
    SMILES
    C1=CC=C(C=C1)C2=C(C(=O)NC(=C2)C3=C(C=CC(=C3)Br)O)C#N
    InChIKey
    SVSYJTYGPLVUOZ-UHFFFAOYSA-N
    InChI
    1S/C18H11BrN2O2/c19-12-6-7-17(22)14(8-12)16-9-13(11-4-2-1-3-5-11)15(10-20)18(23)21-16/h1-9,22H,(H,21,23)
    Synonyms
    SC 204330 | 3-Cyano-4-phenyl-6-(3-bromo-6-hydroxy)phenyl-2(1H)-pyridone | 6-(5-bromo-2-hydroxyphenyl)-2-oxo-4-phenyl-...
  3. AZD1208, Inhibitor of Pim-1 proto-oncogene; serine/threonine kinase;Inhibitor of Pim-2 proto-oncogene; serine/threonine kinase;Inhibitor of Pim-3 proto-oncogene; serine/threonine kinase
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    AZD1208, Inhibitor of Pim-1 proto-oncogene; serine/threonine kinase;Inhibitor of Pim-2 proto-oncogene; serine/threonine kinase;Inhibitor of Pim-3 proto-oncogene; serine/threonine kinase
    CAS: 1204144-28-4 Formula: C21H21N3O2S Molecular Weight: 379.48
    Moligand™ ? Moligand™ — Aladdin's line of ligands and bioactive small molecules. Use for receptor, pathway, and binding studies needing defined small-molecule tools. ≥98%
    In Stock Item #: A127698
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    Technical Identifiers
    IUPAC Name
    (5Z)-5-[[2-[(3R)-3-aminopiperidin-1-yl]-3-phenylphenyl]methylidene]-1,3-thiazolidine-2,4-dione
    SMILES
    C1CC(CN(C1)C2=C(C=CC=C2C3=CC=CC=C3)C=C4C(=O)NC(=O)S4)N
    InChIKey
    MCUJKPPARUPFJM-UWCCDQBKSA-N
    InChI
    1S/C21H21N3O2S/c22-16-9-5-11-24(13-16)19-15(12-18-20(25)23-21(26)27-18)8-4-10-17(19)14-6-2-1-3-7-14/h1-4,6-8,10,12,16H,5,9,11,13,22H2,(H,23,25,26)/b18show more
    Synonyms
    AZD 1208 [WHO-DD] | Q27074698 | FT-0633869 | J-013789 | HY-15604 | S98NFM1378 | SW219766-1 | 1204144-28-4 | AZ-1208 |...
  4. Sotrastaurin, Protein kinase C (PKC) inhibitor
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    Sotrastaurin, Protein kinase C (PKC) inhibitor
    CAS: 425637-18-9 PubChem CID: 10296883 Formula: C25H22N6O2 Molecular Weight: 438.49
    Moligand™ ? Moligand™ — Aladdin's line of ligands and bioactive small molecules. Use for receptor, pathway, and binding studies needing defined small-molecule tools. ≥98%
    In Stock Item #: S125985
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    Technical Identifiers
    IUPAC Name
    3-(1H-indol-3-yl)-4-[2-(4-methylpiperazin-1-yl)quinazolin-4-yl]pyrrole-2,5-dione
    SMILES
    CN1CCN(CC1)C2=NC3=CC=CC=C3C(=N2)C4=C(C(=O)NC4=O)C5=CNC6=CC=CC=C65
    InChIKey
    OAVGBZOFDPFGPJ-UHFFFAOYSA-N
    InChI
    1S/C25H22N6O2/c1-30-10-12-31(13-11-30)25-27-19-9-5-3-7-16(19)22(28-25)21-20(23(32)29-24(21)33)17-14-26-18-8-4-2-6-15(17)18/h2-9,14,26H,10-13H2,1H3,(H,show more
    Synonyms
    AKOS027422723 | 3-(1H-Indol-3-yl)-4-(2-(4-methylpiperazin-1-yl)quinazolin-4-yl)-1H-pyrrole-2,5-dione | EX-A2802 | 105...
  5. AZD1208, Inhibitor of Pim-1 proto-oncogene; serine/threonine kinase;Inhibitor of Pim-2 proto-oncogene; serine/threonine kinase;Inhibitor of Pim-3 proto-oncogene; serine/threonine kinase
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    AZD1208, Inhibitor of Pim-1 proto-oncogene; serine/threonine kinase;Inhibitor of Pim-2 proto-oncogene; serine/threonine kinase;Inhibitor of Pim-3 proto-oncogene; serine/threonine kinase
    CAS: 1204144-28-4 Formula: C21H21N3O2S Molecular Weight: 379.48
    Moligand™ ? Moligand™ — Aladdin's line of ligands and bioactive small molecules. Use for receptor, pathway, and binding studies needing defined small-molecule tools. 10mM in DMSO
    Out of Stock Item #: A420898
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    Technical Identifiers
    IUPAC Name
    (5Z)-5-[[2-[(3R)-3-aminopiperidin-1-yl]-3-phenylphenyl]methylidene]-1,3-thiazolidine-2,4-dione
    SMILES
    C1CC(CN(C1)C2=C(C=CC=C2C3=CC=CC=C3)C=C4C(=O)NC(=O)S4)N
    InChIKey
    MCUJKPPARUPFJM-UWCCDQBKSA-N
    InChI
    1S/C21H21N3O2S/c22-16-9-5-11-24(13-16)19-15(12-18-20(25)23-21(26)27-18)8-4-10-17(19)14-6-2-1-3-7-14/h1-4,6-8,10,12,16H,5,9,11,13,22H2,(H,23,25,26)/b18show more
    Synonyms
    AZD 1208 [WHO-DD] | Q27074698 | FT-0633869 | J-013789 | HY-15604 | S98NFM1378 | SW219766-1 | 1204144-28-4 | AZ-1208 |...
  6. CX-6258, Inhibitor of Pim-1 proto-oncogene; serine/threonine kinase;Inhibitor of Pim-2 proto-oncogene; serine/threonine kinase;Inhibitor of Pim-3 proto-oncogene; serine/threonine kinase
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    CX-6258, Inhibitor of Pim-1 proto-oncogene; serine/threonine kinase;Inhibitor of Pim-2 proto-oncogene; serine/threonine kinase;Inhibitor of Pim-3 proto-oncogene; serine/threonine kinase
    CAS: 1202916-90-2 Formula: C26H24ClN3O3 Molecular Weight: 461.94
    Moligand™ ? Moligand™ — Aladdin's line of ligands and bioactive small molecules. Use for receptor, pathway, and binding studies needing defined small-molecule tools. ≥98%
    In Stock Item #: C126466
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    IUPAC Name
    (3E)-5-chloro-3-[[5-[3-(4-methyl-1,4-diazepane-1-carbonyl)phenyl]furan-2-yl]methylidene]-1H-indol-2-one
    SMILES
    CN1CCCN(CC1)C(=O)C2=CC=CC(=C2)C3=CC=C(O3)C=C4C5=C(C=CC(=C5)Cl)NC4=O
    InChIKey
    KGBPLKOPSFDBOX-CJLVFECKSA-N
    InChI
    1S/C26H24ClN3O3/c1-29-10-3-11-30(13-12-29)26(32)18-5-2-4-17(14-18)24-9-7-20(33-24)16-22-21-15-19(27)6-8-23(21)28-25(22)31/h2,4-9,14-16H,3,10-13H2,1H3,show more
    Synonyms
    CX6258 | CX 6258 | (3E)-5-Chloro-3-[[5-[3-[(hexahydro-4-methyl-1H-1,4-diazepin-1-yl)carbonyl]phenyl]-2-furanyl]methyl...
  7. HS 38
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    HS 38
    CAS: 1030203-81-6 EC Number: 808-443-9 Formula: C14H12CIN5O2S Molecular Weight: 349.8
    ≥98%(HPLC)
    In Stock Item #: H287038
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    Technical Identifiers
    IUPAC Name
    2-[[1-(3-chlorophenyl)-4-oxo-5H-pyrazolo[3,4-d]pyrimidin-6-yl]sulfanyl]propanamide
    SMILES
    CC(C(=O)N)SC1=NC2=C(C=NN2C3=CC(=CC=C3)Cl)C(=O)N1
    InChIKey
    NASYEGAVCTZSDO-UHFFFAOYSA-N
    InChI
    1S/C14H12ClN5O2S/c1-7(11(16)21)23-14-18-12-10(13(22)19-14)6-17-20(12)9-4-2-3-8(15)5-9/h2-7H,1H3,(H2,16,21)(H,18,19,22)
    Synonyms
    Z247384094 | 2-[[1-(3-chlorophenyl)-4-oxo-5H-pyrazolo[3,4-d]pyrimidin-6-yl]sulfanyl]propanamide | 1030203-81-6 | AKOS...
  8. NSC 31205
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    NSC 31205
    CAS: 6320-51-0 Formula: C11H9NO3S Molecular Weight: 235.257
    ≥98%
    In Stock Item #: N412279
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    Technical Identifiers
    IUPAC Name
    (5Z)-5-[(4-methoxyphenyl)methylidene]-1,3-thiazolidine-2,4-dione
    SMILES
    COC1=CC=C(C=C1)C=C2C(=O)NC(=O)S2
    InChIKey
    VRUKGUBMRBLJJW-TWGQIWQCSA-N
    InChI
    1S/C11H9NO3S/c1-15-8-4-2-7(3-5-8)6-9-10(13)12-11(14)16-9/h2-6H,1H3,(H,12,13,14)/b9-6-
    Synonyms
    5-(4-methoxybenzylidene)thiazolidine-2,4-dione | 5-(4-methoxybenzylidene)-1,3-thiazolidine-2,4-dione | HMS1414C03 | M...
  9. NSC 31205
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    NSC 31205
    CAS: 6320-51-0 Formula: C11H9NO3S Molecular Weight: 235.257
    10mM in DMSO
    Out of Stock Item #: N425201
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    Technical Identifiers
    IUPAC Name
    (5Z)-5-[(4-methoxyphenyl)methylidene]-1,3-thiazolidine-2,4-dione
    SMILES
    COC1=CC=C(C=C1)C=C2C(=O)NC(=O)S2
    InChIKey
    VRUKGUBMRBLJJW-TWGQIWQCSA-N
    InChI
    1S/C11H9NO3S/c1-15-8-4-2-7(3-5-8)6-9-10(13)12-11(14)16-9/h2-6H,1H3,(H,12,13,14)/b9-6-
    Synonyms
    5-(4-methoxybenzylidene)thiazolidine-2,4-dione | 5-(4-methoxybenzylidene)-1,3-thiazolidine-2,4-dione | HMS1414C03 | M...
  10. PIM447 (LGH447), Inhibitor of Pim-1 proto-oncogene; serine/threonine kinase;Inhibitor of Pim-2 proto-oncogene; serine/threonine kinase;Inhibitor of Pim-3 proto-oncogene; serine/threonine kinase
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    PIM447 (LGH447), Inhibitor of Pim-1 proto-oncogene; serine/threonine kinase;Inhibitor of Pim-2 proto-oncogene; serine/threonine kinase;Inhibitor of Pim-3 proto-oncogene; serine/threonine kinase
    CAS: 1210608-43-7(freebase) PubChem CID: 44814409 Formula: C24H23F3N4O.HCl Molecular Weight: 476.92
    Moligand™ ? Moligand™ — Aladdin's line of ligands and bioactive small molecules. Use for receptor, pathway, and binding studies needing defined small-molecule tools. ≥97%
    Out of Stock Item #: P413900
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    IUPAC Name
    N-[4-[(1R,3S,5S)-3-amino-5-methylcyclohexyl]pyridin-3-yl]-6-(2,6-difluorophenyl)-5-fluoropyridine-2-carboxamide
    SMILES
    CC1CC(CC(C1)N)C2=C(C=NC=C2)NC(=O)C3=NC(=C(C=C3)F)C4=C(C=CC=C4F)F
    InChIKey
    VRQXRVAKPDCRCI-ZNMIVQPWSA-N
    InChI
    1S/C24H23F3N4O/c1-13-9-14(11-15(28)10-13)16-7-8-29-12-21(16)31-24(32)20-6-5-19(27)23(30-20)22-17(25)3-2-4-18(22)26/h2-8,12-15H,9-11,28H2,1H3,(H,31,32)show more
    Synonyms
    5H7 | A903354 | GTPL9790 | yl)-6-(2,6-difluorophenyl)-5-fluoropicolinamide | SODIUM CYANIDE [MI] | US8592455, 70 | PI...
  11. Quercetin 3-rhamnoside
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    Quercetin 3-rhamnoside
    CAS: 522-12-3 EC Number: 208-322-5 PubChem CID: 5280459 Formula: C21H20O11 Molecular Weight: 448.38
    10mM in DMSO
    In Stock Item #: Q424472
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    Technical Identifiers
    IUPAC Name
    2-(3,4-dihydroxyphenyl)-5,7-dihydroxy-3-[(2S,3R,4R,5R,6S)-3,4,5-trihydroxy-6-methyloxan-2-yl]oxychromen-4-one
    SMILES
    CC1C(C(C(C(O1)OC2=C(OC3=CC(=CC(=C3C2=O)O)O)C4=CC(=C(C=C4)O)O)O)O)O
    InChIKey
    OXGUCUVFOIWWQJ-HQBVPOQASA-N
    InChI
    1S/C21H20O11/c1-7-15(26)17(28)18(29)21(30-7)32-20-16(27)14-12(25)5-9(22)6-13(14)31-19(20)8-2-3-10(23)11(24)4-8/h2-7,15,17-18,21-26,28-29H,1H3/t7-,15-,show more
    Synonyms
    3-O-a-L-Rhamnopyranosyloxy-3',4',5,7-tetrahydroxyflavone | NCI-C60102 | Quercitroside | 4H-1-Benzopyran-4-one, 3-[(6-...
  12. Quercetin 3-rhamnoside
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    Quercetin 3-rhamnoside
    CAS: 522-12-3 EC Number: 208-322-5 PubChem CID: 5280459 Formula: C21H20O11 Molecular Weight: 448.38
    Analytical standard ? Analytical standard — certified-purity material for quantitative calibration. Use to prepare calibration standards and validate analytical methods. ≥98%
    In Stock Item #: Q109798
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    Technical Identifiers
    IUPAC Name
    2-(3,4-dihydroxyphenyl)-5,7-dihydroxy-3-[(2S,3R,4R,5R,6S)-3,4,5-trihydroxy-6-methyloxan-2-yl]oxychromen-4-one
    SMILES
    CC1C(C(C(C(O1)OC2=C(OC3=CC(=CC(=C3C2=O)O)O)C4=CC(=C(C=C4)O)O)O)O)O
    InChIKey
    OXGUCUVFOIWWQJ-HQBVPOQASA-N
    InChI
    1S/C21H20O11/c1-7-15(26)17(28)18(29)21(30-7)32-20-16(27)14-12(25)5-9(22)6-13(14)31-19(20)8-2-3-10(23)11(24)4-8/h2-7,15,17-18,21-26,28-29H,1H3/t7-,15-,show more
    Synonyms
    3-O-a-L-Rhamnopyranosyloxy-3',4',5,7-tetrahydroxyflavone | NCI-C60102 | Quercitroside | 4H-1-Benzopyran-4-one, 3-[(6-...
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