Ste20-like serine/threonine-protein kinase (SLK)

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  1. Icotinib, Epidermal growth factor receptor erbB1 inhibitor
    CAS: 610798-31-7 Formula: C22H21N3O4 Molecular Weight: 391.42
    Moligand™ ? Moligand™ — Aladdin's line of ligands and bioactive small molecules. Use for receptor, pathway, and binding studies needing defined small-molecule tools. ≥99%
    In Stock Item #: I129405
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    IUPAC Name
    N-(3-ethynylphenyl)-2,5,8,11-tetraoxa-15,17-diazatricyclo[10.8.0.014,19]icosa-1(12),13,15,17,19-pentaen-18-amine
    SMILES
    C#CC1=CC(=CC=C1)NC2=NC=NC3=CC4=C(C=C32)OCCOCCOCCO4
    InChIKey
    QQLKULDARVNMAL-UHFFFAOYSA-N
    InChI
    1S/C22H21N3O4/c1-2-16-4-3-5-17(12-16)25-22-18-13-20-21(14-19(18)23-15-24-22)29-11-9-27-7-6-26-8-10-28-20/h1,3-5,12-15H,6-11H2,(H,23,24,25)
    Synonyms
    N-(3-ethynylphenyl)-2,5,8,11-tetraoxa-15,17-diazatricyclo[10.8.0.014,19]icosa-1(12),13,15,17,19-pentaen-18-amine | Q1...
  2. GW843682X
    CAS: 660868-91-7 EC Number: 636-269-1 Formula: C22H18F3N3O4S Molecular Weight: 477.46
    Out of Stock Item #: G127325
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    IUPAC Name
    5-(5,6-dimethoxybenzimidazol-1-yl)-3-[[2-(trifluoromethyl)phenyl]methoxy]thiophene-2-carboxamide
    SMILES
    COC1=C(C=C2C(=C1)N=CN2C3=CC(=C(S3)C(=O)N)OCC4=CC=CC=C4C(F)(F)F)OC
    InChIKey
    JSKUWFIZUALZLX-UHFFFAOYSA-N
    InChI
    1S/C22H18F3N3O4S/c1-30-16-7-14-15(8-17(16)31-2)28(11-27-14)19-9-18(20(33-19)21(26)29)32-10-12-5-3-4-6-13(12)22(23,24)25/h3-9,11H,10H2,1-2H3,(H2,26,29)
    Synonyms
    UNII-D130E8V1ON | BFHKYHMCIAMQIN-UHFFFAOYSA-N | HMS3677H06 | NSC756404 | NSC-756404 | GW 843682X; GW-843682X | SCHEMB...
  3. Icotinib (BPI-2009H), Epidermal growth factor receptor erbB1 inhibitor
    CAS: 610798-31-7 Formula: C22H21N3O4 Molecular Weight: 391.42
    Moligand™ ? Moligand™ — Aladdin's line of ligands and bioactive small molecules. Use for receptor, pathway, and binding studies needing defined small-molecule tools. 10mM in DMSO
    In Stock Item #: I408103
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    Synonyms
    [1,4,7,10]Tetraoxacyclododecino[2,3-g]quinazolin-4-amine, N-(3-ethynylphenyl)-7,8,10,11,13,14-hexahydro-
  4. RN486, Inhibitor of Bruton tyrosine kinase;Inhibitor of STE20 like kinase
    CAS: 1242156-23-5 PubChem CID: 46908026 Formula: C35H35FN6O3 Molecular Weight: 606.69
    Moligand™ ? Moligand™ — Aladdin's line of ligands and bioactive small molecules. Use for receptor, pathway, and binding studies needing defined small-molecule tools. ≥98%
    In Stock Item #: R413708
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    Technical Identifiers
    IUPAC Name
    6-cyclopropyl-8-fluoro-2-[2-(hydroxymethyl)-3-[1-methyl-5-[[5-(4-methylpiperazin-1-yl)pyridin-2-yl]amino]-6-oxopyridin-3-yl]phenyl]isoquinolin-1-one
    SMILES
    CN1CCN(CC1)C2=CN=C(C=C2)NC3=CC(=CN(C3=O)C)C4=C(C(=CC=C4)N5C=CC6=CC(=CC(=C6C5=O)F)C7CC7)CO
    InChIKey
    ZTUJNJAKTLHBEX-UHFFFAOYSA-N
    InChI
    1S/C35H35FN6O3/c1-39-12-14-41(15-13-39)26-8-9-32(37-19-26)38-30-18-25(20-40(2)34(30)44)27-4-3-5-31(28(27)21-43)42-11-10-23-16-24(22-6-7-22)17-29(36)33show more
    Synonyms
    FT-0700142 | RN486 | RN-486 | 7G6 | 6-Cyclopropyl-8-Fluoranyl-2-[2-(Hydroxymethyl)-3-[1-Methyl-5-[[5-(4-Methylpiperaz...
  5. RN486, Inhibitor of Bruton tyrosine kinase;Inhibitor of STE20 like kinase
    CAS: 1242156-23-5 PubChem CID: 46908026 Formula: C35H35FN6O3 Molecular Weight: 606.69
    Moligand™ ? Moligand™ — Aladdin's line of ligands and bioactive small molecules. Use for receptor, pathway, and binding studies needing defined small-molecule tools. 10mM in DMSO
    In Stock Item #: R421041
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    Technical Identifiers
    IUPAC Name
    6-cyclopropyl-8-fluoro-2-[2-(hydroxymethyl)-3-[1-methyl-5-[[5-(4-methylpiperazin-1-yl)pyridin-2-yl]amino]-6-oxopyridin-3-yl]phenyl]isoquinolin-1-one
    SMILES
    CN1CCN(CC1)C2=CN=C(C=C2)NC3=CC(=CN(C3=O)C)C4=C(C(=CC=C4)N5C=CC6=CC(=CC(=C6C5=O)F)C7CC7)CO
    InChIKey
    ZTUJNJAKTLHBEX-UHFFFAOYSA-N
    InChI
    1S/C35H35FN6O3/c1-39-12-14-41(15-13-39)26-8-9-32(37-19-26)38-30-18-25(20-40(2)34(30)44)27-4-3-5-31(28(27)21-43)42-11-10-23-16-24(22-6-7-22)17-29(36)33show more
    Synonyms
    FT-0700142 | RN486 | RN-486 | 7G6 | 6-Cyclopropyl-8-Fluoranyl-2-[2-(Hydroxymethyl)-3-[1-Methyl-5-[[5-(4-Methylpiperaz...
  6. GW843682X
    CAS: 660868-91-7 EC Number: 636-269-1 Formula: C22H18F3N3O4S Molecular Weight: 477.46
    Moligand™ ? Moligand™ — Aladdin's line of ligands and bioactive small molecules. Use for receptor, pathway, and binding studies needing defined small-molecule tools. 10 mM in DMSO
    Out of Stock Item #: G1494338
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  7. 6-Amino-4-(2-fluorophenyl)-3-methyl-1,4-dihydropyrano[2,3-c]pyrazole-5-carbonitrile
    CAS: 89607-35-2 EC Number: 168-000-4 PubChem CID: 600140 Formula: C14H11FN4O Molecular Weight: 270.27
    Out of Stock Item #: A1054922
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    Technical Identifiers
    IUPAC Name
    6-amino-4-(2-fluorophenyl)-3-methyl-2,4-dihydropyrano[2,3-c]pyrazole-5-carbonitrile
    SMILES
    CC1=C2C(C(=C(OC2=NN1)N)C#N)C3=CC=CC=C3F
    InChIKey
    VCYNMKHKCLKODE-UHFFFAOYSA-N
    InChI
    1S/C14H11FN4O/c1-7-11-12(8-4-2-3-5-10(8)15)9(6-16)13(17)20-14(11)19-18-7/h2-5,12H,17H2,1H3,(H,18,19)
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