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Tgf-beta receptor type-2 (TGFBR2)

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  1. LY2109761, Inhibitor of transforming growth factor beta receptor 1;Inhibitor of transforming growth factor beta receptor 2
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    LY2109761, Inhibitor of transforming growth factor beta receptor 1;Inhibitor of transforming growth factor beta receptor 2
    CAS: 700874-71-1 Formula: C26H27N5O2 Molecular Weight: 441.52
    Moligand™ ? Moligand™ — Aladdin's line of ligands and bioactive small molecules. Use for receptor, pathway, and binding studies needing defined small-molecule tools. ≥99%
    In Stock Item #: L126135
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    IUPAC Name
    4-[2-[4-(2-pyridin-2-yl-5,6-dihydro-4H-pyrrolo[1,2-b]pyrazol-3-yl)quinolin-7-yl]oxyethyl]morpholine
    SMILES
    C1CC2=C(C(=NN2C1)C3=CC=CC=N3)C4=C5C=CC(=CC5=NC=C4)OCCN6CCOCC6
    InChIKey
    IHLVSLOZUHKNMQ-UHFFFAOYSA-N
    InChI
    1S/C26H27N5O2/c1-2-9-27-22(4-1)26-25(24-5-3-11-31(24)29-26)21-8-10-28-23-18-19(6-7-20(21)23)33-17-14-30-12-15-32-16-13-30/h1-2,4,6-10,18H,3,5,11-17H2
    Synonyms
    HMS3674E17 | SB19481 | AKOS022183732 | GTPL8075 | BCP9000868 | LY 2109761 | Q27082613 | .ALPHA.-KETOGLUCONIC ACID | Q...
  2. SB431542 - ≥98%, used for , CAS No. 301836-41-9, by Aladdin Scientific
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    SB431542, Inhibitor of activin A receptor type 1C;Inhibitor of transforming growth factor beta receptor 1
    CAS: 301836-41-9 EC Number: 188-365-3 Formula: C22H16N4O3 Molecular Weight: 384.39
    Solid Moligand™ ? Moligand™ — Aladdin's line of ligands and bioactive small molecules. Use for receptor, pathway, and binding studies needing defined small-molecule tools. ≥98%
    In Stock Item #: S125924
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    IUPAC Name
    4-[4-(1,3-benzodioxol-5-yl)-5-pyridin-2-yl-1H-imidazol-2-yl]benzamide
    SMILES
    C1OC2=C(O1)C=C(C=C2)C3=C(NC(=N3)C4=CC=C(C=C4)C(=O)N)C5=CC=CC=N5
    InChIKey
    FHYUGAJXYORMHI-UHFFFAOYSA-N
    InChI
    1S/C22H16N4O3/c23-21(27)13-4-6-14(7-5-13)22-25-19(20(26-22)16-3-1-2-10-24-16)15-8-9-17-18(11-15)29-12-28-17/h1-11H,12H2,(H2,23,27)(H,25,26)
    Synonyms
    4-(4-(benzo[d][1,3]dioxol-5-yl)-5-(pyridin-2-yl)-1H-imidazol-2-yl)benzamide | 4-[4-(1,3-BENZODIOXOL-5-YL)-5-(2-PYRIDI...
  3. ITD-1
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    ITD-1
    CAS: 1099644-42-4 Formula: C27H29NO3 Molecular Weight: 415.52
    ≥98%
    In Stock Item #: I302185
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    IUPAC Name
    ethyl 2,7,7-trimethyl-5-oxo-4-(4-phenylphenyl)-1,4,6,8-tetrahydroquinoline-3-carboxylate
    SMILES
    CCOC(=O)C1=C(NC2=C(C1C3=CC=C(C=C3)C4=CC=CC=C4)C(=O)CC(C2)(C)C)C
    InChIKey
    ULFUJLFTRWWLPO-UHFFFAOYSA-N
    InChI
    1S/C27H29NO3/c1-5-31-26(30)23-17(2)28-21-15-27(3,4)16-22(29)25(21)24(23)20-13-11-19(12-14-20)18-9-7-6-8-10-18/h6-14,24,28H,5,15-16H2,1-4H3
    Synonyms
    Ethyl 4-([1,1'-biphenyl]-4-yl)-2,7,7-trimethyl-5-oxo-1,4,5,6,7,8-hexahydroquinoline-3-carboxylate
  4. LDN 212854
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    LDN 212854
    CAS: 1432597-26-6 EC Number: 808-898-3 Formula: C25H22N6 Molecular Weight: 406.48
    ≥98%(HPLC)
    In Stock Item #: L286865
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    IUPAC Name
    5-[6-(4-piperazin-1-ylphenyl)pyrazolo[1,5-a]pyrimidin-3-yl]quinoline
    SMILES
    C1CN(CCN1)C2=CC=C(C=C2)C3=CN4C(=C(C=N4)C5=C6C=CC=NC6=CC=C5)N=C3
    InChIKey
    BBDGBGOVJPEFBT-UHFFFAOYSA-N
    InChI
    1S/C25H22N6/c1-3-21(22-4-2-10-27-24(22)5-1)23-16-29-31-17-19(15-28-25(23)31)18-6-8-20(9-7-18)30-13-11-26-12-14-30/h1-10,15-17,26H,11-14H2
    Synonyms
    SB19484 | BDBM102618 | CCG-268725 | LDN 212854 | C72696 | BCP08633 | 5-(6-(4-(1-Piperazinyl)phenyl)pyrazolo[1,5-a]pyr...
  5. LY364947, Inhibitor of transforming growth factor beta receptor 1
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    LY364947, Inhibitor of transforming growth factor beta receptor 1
    CAS: 396129-53-6 EC Number: 636-801-2 Formula: C17H12N4 Molecular Weight: 272.3
    Moligand™ ? Moligand™ — Aladdin's line of ligands and bioactive small molecules. Use for receptor, pathway, and binding studies needing defined small-molecule tools. ≥98%
    In Stock Item #: L129343
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    IUPAC Name
    4-(5-pyridin-2-yl-1H-pyrazol-4-yl)quinoline
    SMILES
    C1=CC=C2C(=C1)C(=CC=N2)C3=C(NN=C3)C4=CC=CC=N4
    InChIKey
    IBCXZJCWDGCXQT-UHFFFAOYSA-N
    InChI
    1S/C17H12N4/c1-2-6-15-13(5-1)12(8-10-19-15)14-11-20-21-17(14)16-7-3-4-9-18-16/h1-11H,(H,20,21)
    Synonyms
    SB19489 | 4-(3-PYRIDIN-2-YL-1H-PYRAZOL-4-YL)QUINOLINE | s2805 | HMS3229M09 | PY1 | 4-[3-(2-Pyridinyl)-1H-pyrazol-4-yl...
  6. BMS-986260, Inhibitor of activin A receptor type 1;Inhibitor of activin A receptor type 1B;Inhibitor of transforming growth factor beta receptor 1
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    BMS-986260, Inhibitor of activin A receptor type 1;Inhibitor of activin A receptor type 1B;Inhibitor of transforming growth factor beta receptor 1
    CAS: 2001559-19-7 Formula: C18H12ClFN6O Molecular Weight: 382.8
    Moligand™ ? Moligand™ — Aladdin's line of ligands and bioactive small molecules. Use for receptor, pathway, and binding studies needing defined small-molecule tools. ≥98%
    In Stock Item #: B412813
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    Technical Identifiers
    IUPAC Name
    6-[5-(3-chloro-4-fluorophenyl)-3-(2-hydroxyethyl)imidazol-4-yl]imidazo[1,2-b]pyridazine-3-carbonitrile
    SMILES
    C1=CC(=C(C=C1C2=C(N(C=N2)CCO)C3=NN4C(=NC=C4C#N)C=C3)Cl)F
    InChIKey
    VZZBCNXVZFAIQX-UHFFFAOYSA-N
    InChI
    1S/C18H12ClFN6O/c19-13-7-11(1-2-14(13)20)17-18(25(5-6-27)10-23-17)15-3-4-16-22-9-12(8-21)26(16)24-15/h1-4,7,9-10,27H,5-6H2
    Synonyms
    BMS986260 | BMS-986260 | GTPL10662 | EX-A7758 | AKOS040759507 | 2001559-19-7 | HY-W107024 | SCHEMBL18041543 | AT27405...
  7. ITD-1
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    ITD-1
    CAS: 1099644-42-4 Formula: C27H29NO3 Molecular Weight: 415.52
    10mM in DMSO
    In Stock Item #: I420581
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    Technical Identifiers
    IUPAC Name
    ethyl 2,7,7-trimethyl-5-oxo-4-(4-phenylphenyl)-1,4,6,8-tetrahydroquinoline-3-carboxylate
    SMILES
    CCOC(=O)C1=C(NC2=C(C1C3=CC=C(C=C3)C4=CC=CC=C4)C(=O)CC(C2)(C)C)C
    InChIKey
    ULFUJLFTRWWLPO-UHFFFAOYSA-N
    InChI
    1S/C27H29NO3/c1-5-31-26(30)23-17(2)28-21-15-27(3,4)16-22(29)25(21)24(23)20-13-11-19(12-14-20)18-9-7-6-8-10-18/h6-14,24,28H,5,15-16H2,1-4H3
    Synonyms
    ITD 14-[1,1'-Biphenyl]-4-yl-1,4,5,6,7,8-hexahydro-2,7,7-trimethyl-5-oxo-3-quinolinecarboxylic acid ethyl ester
  8. LDN 212854
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    LDN 212854
    CAS: 1432597-26-6 EC Number: 808-898-3 Formula: C25H22N6 Molecular Weight: 406.48
    10mM in DMSO
    In Stock Item #: L421597
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    Technical Identifiers
    IUPAC Name
    5-[6-(4-piperazin-1-ylphenyl)pyrazolo[1,5-a]pyrimidin-3-yl]quinoline
    SMILES
    C1CN(CCN1)C2=CC=C(C=C2)C3=CN4C(=C(C=N4)C5=C6C=CC=NC6=CC=C5)N=C3
    InChIKey
    BBDGBGOVJPEFBT-UHFFFAOYSA-N
    InChI
    1S/C25H22N6/c1-3-21(22-4-2-10-27-24(22)5-1)23-16-29-31-17-19(15-28-25(23)31)18-6-8-20(9-7-18)30-13-11-26-12-14-30/h1-10,15-17,26H,11-14H2
    Synonyms
    SB19484 | BDBM102618 | CCG-268725 | LDN 212854 | C72696 | BCP08633 | 5-(6-(4-(1-Piperazinyl)phenyl)pyrazolo[1,5-a]pyr...
  9. LY2109761, Inhibitor of transforming growth factor beta receptor 1;Inhibitor of transforming growth factor beta receptor 2
    Wish List Compare
    LY2109761, Inhibitor of transforming growth factor beta receptor 1;Inhibitor of transforming growth factor beta receptor 2
    CAS: 700874-71-1 Formula: C26H27N5O2 Molecular Weight: 441.52
    Moligand™ ? Moligand™ — Aladdin's line of ligands and bioactive small molecules. Use for receptor, pathway, and binding studies needing defined small-molecule tools. 2mM in DMSO
    In Stock Item #: L408237
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    Technical Identifiers
    Synonyms
    7-(2-morpholinoethoxy)-4-(2-(pyridin-2-yl)-5,6-dihydro-4H-pyrrolo[1,2-b]pyrazol-3-yl)quinoline
  10. LY364947, Inhibitor of transforming growth factor beta receptor 1
    Wish List Compare
    LY364947, Inhibitor of transforming growth factor beta receptor 1
    CAS: 396129-53-6 EC Number: 636-801-2 Formula: C17H12N4 Molecular Weight: 272.3
    Moligand™ ? Moligand™ — Aladdin's line of ligands and bioactive small molecules. Use for receptor, pathway, and binding studies needing defined small-molecule tools. 2mM in DMSO
    In Stock Item #: L423823
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    Technical Identifiers
    IUPAC Name
    4-(5-pyridin-2-yl-1H-pyrazol-4-yl)quinoline
    SMILES
    C1=CC=C2C(=C1)C(=CC=N2)C3=C(NN=C3)C4=CC=CC=N4
    InChIKey
    IBCXZJCWDGCXQT-UHFFFAOYSA-N
    InChI
    1S/C17H12N4/c1-2-6-15-13(5-1)12(8-10-19-15)14-11-20-21-17(14)16-7-3-4-9-18-16/h1-11H,(H,20,21)
    Synonyms
    SB19489 | 4-(3-PYRIDIN-2-YL-1H-PYRAZOL-4-YL)QUINOLINE | s2805 | HMS3229M09 | PY1 | 4-[3-(2-Pyridinyl)-1H-pyrazol-4-yl...
  11. SB431542, Inhibitor of activin A receptor type 1C;Inhibitor of transforming growth factor beta receptor 1
    Wish List Compare
    SB431542, Inhibitor of activin A receptor type 1C;Inhibitor of transforming growth factor beta receptor 1
    CAS: 301836-41-9 EC Number: 188-365-3 Formula: C22H16N4O3 Molecular Weight: 384.39
    Moligand™ ? Moligand™ — Aladdin's line of ligands and bioactive small molecules. Use for receptor, pathway, and binding studies needing defined small-molecule tools. 10mM in DMSO
    Out of Stock Item #: S408658
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    Technical Identifiers
    Synonyms
    4-(4-(benzo[d][1,3]dioxol-5-yl)-5-(pyridin-2-yl)-1H-imidazol-2-yl)benzamide
  12. no_selection
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    3-[6-(2-pyridin-2-yl-5,6-dihydro-4H-pyrrolo[2,1-e]pyrazol-3-yl)benzimidazol-1-yl]propan-1-ol, Inhibitor of transforming growth factor beta receptor 1;Inhibitor of transforming growth factor beta receptor 2;Inhibitor of ZAK sterile alpha motif and leucine zipper containing kinase AZK
    Moligand™ ? Moligand™ — Aladdin's line of ligands and bioactive small molecules. Use for receptor, pathway, and binding studies needing defined small-molecule tools.
    Out of Stock Item #: P608741
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    Technical Identifiers
    IUPAC Name
    3-[6-(2-pyridin-2-yl-5,6-dihydro-4H-pyrrolo[2,1-e]pyrazol-3-yl)benzimidazol-1-yl]propan-1-ol
    SMILES
    OCCCn1cnc2c1cc(cc2)c1c2CCCn2nc1c1ccccn1
    InChIKey
    SYCWRTUPLPDKDX-UHFFFAOYSA-N
    InChI
    1S/C21H21N5O/c27-12-4-10-25-14-23-16-8-7-15(13-19(16)25)20-18-6-3-11-26(18)24-21(20)17-5-1-2-9-22-17/h1-2,5,7-9,13-14,27H,3-4,6,10-12H2
    Synonyms
    compound 15b
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