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Tyrosine-protein kinase zap-70 (ZAP70)

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  1. Tyrphostin 23
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    Tyrphostin 23
    CAS: 118409-57-7 EC Number: 834-432-3 PubChem CID: 2052 Formula: C10H6N2O2 Molecular Weight: 186.17
    ≥98%
    In Stock Item #: T129445
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    Technical Identifiers
    IUPAC Name
    2-[(3,4-dihydroxyphenyl)methylidene]propanedinitrile
    SMILES
    C1=CC(=C(C=C1C=C(C#N)C#N)O)O
    InChIKey
    VTJXFTPMFYAJJU-UHFFFAOYSA-N
    InChI
    1S/C10H6N2O2/c11-5-8(6-12)3-7-1-2-9(13)10(14)4-7/h1-4,13-14H
    Synonyms
    AG18;Tyrphostin 23; RG-50810 | MLS002153315 | NCGC00016043-03 | AG 18 (Tyrphostin 23) | HMS3414G15 | SMR001230729 | T...
  2. AG-18
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    AG-18
    CAS: 118409-57-7 EC Number: 834-432-3 PubChem CID: 2052 Formula: C10H6N2O2 Molecular Weight: 186.17
    10mM in DMSO
    In Stock Item #: A408794
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    Synonyms
    RG-50810, Tyrphostin A23, TX 825 | Propanedinitrile, 2-[(3,4-dihydroxyphenyl)methylene]-
  3. SU11274, Inhibitor of MET proto-oncogene; receptor tyrosine kinase
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    SU11274, Inhibitor of MET proto-oncogene; receptor tyrosine kinase
    CAS: 658084-23-2 EC Number: 636-258-1 PubChem CID: 9549297 Formula: C28H30CIN5O4S Molecular Weight: 568.09
    Moligand™ ? Moligand™ — Aladdin's line of ligands and bioactive small molecules. Use for receptor, pathway, and binding studies needing defined small-molecule tools. ≥97%
    In Stock Item #: S126117
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    IUPAC Name
    (3Z)-N-(3-chlorophenyl)-3-[[3,5-dimethyl-4-(4-methylpiperazine-1-carbonyl)-1H-pyrrol-2-yl]methylidene]-N-methyl-2-oxo-1H-indole-5-sulfonamide
    SMILES
    CC1=C(NC(=C1C(=O)N2CCN(CC2)C)C)C=C3C4=C(C=CC(=C4)S(=O)(=O)N(C)C5=CC(=CC=C5)Cl)NC3=O
    InChIKey
    FPYJSJDOHRDAMT-KQWNVCNZSA-N
    InChI
    1S/C28H30ClN5O4S/c1-17-25(30-18(2)26(17)28(36)34-12-10-32(3)11-13-34)16-23-22-15-21(8-9-24(22)31-27(23)35)39(37,38)33(4)20-7-5-6-19(29)14-20/h5-9,14-1show more
    Synonyms
    BDBM50341636 | (3Z)-N-(3-chlorophenyl)-3-({3,5-dimethyl-4-[(4-methylpiperazin-1-yl)carbonyl]-1H-pyrrol-2-yl}methylide...
  4. SU11274, Inhibitor of MET proto-oncogene; receptor tyrosine kinase
    Wish List Compare
    SU11274, Inhibitor of MET proto-oncogene; receptor tyrosine kinase
    CAS: 658084-23-2 EC Number: 636-258-1 PubChem CID: 9549297 Formula: C28H30CIN5O4S Molecular Weight: 568.09
    Moligand™ ? Moligand™ — Aladdin's line of ligands and bioactive small molecules. Use for receptor, pathway, and binding studies needing defined small-molecule tools. 10mM in DMSO
    In Stock Item #: S408451
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    Technical Identifiers
    Synonyms
    PKI-SU11274 | (Z)-N-(3-chlorophenyl)-3-((3,5-dimethyl-4-(1-methylpiperazine-4-carbonyl)-1H-pyrrol-2-yl)methylene)-N-m...
  5. no_selection
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    2-fluoro-N-methyl-4-[[4-(2-methyl-3-propan-2-ylimidazol-4-yl)pyrimidin-2-yl]amino]benzamide, Inhibitor of cyclin dependent kinase 1;Inhibitor of cyclin dependent kinase 2;Inhibitor of cyclin dependent kinase 4;Inhibitor of cyclin dependent kinase like 1
    Moligand™ ? Moligand™ — Aladdin's line of ligands and bioactive small molecules. Use for receptor, pathway, and binding studies needing defined small-molecule tools.
    Out of Stock Item #: F609478
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    IUPAC Name
    2-fluoro-N-methyl-4-[[4-(2-methyl-3-propan-2-ylimidazol-4-yl)pyrimidin-2-yl]amino]benzamide
    SMILES
    CNC(=O)c1ccc(cc1F)Nc1nccc(n1)c1cnc(n1C(C)C)C
    InChIKey
    OCUYCOQPRGFQEV-UHFFFAOYSA-N
    InChI
    1S/C19H21FN6O/c1-11(2)26-12(3)23-10-17(26)16-7-8-22-19(25-16)24-13-5-6-14(15(20)9-13)18(27)21-4/h5-11H,1-4H3,(H,21,27)(H,22,24,25)
    Synonyms
    compound 9b
  6. no_selection
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    Syk inhibitor II, Inhibitor of spleen associated tyrosine kinase;Inhibitor of zeta chain of T cell receptor associated protein kinase 70
    CAS: 726695-51-8 PubChem CID: 9549296
    Moligand™ ? Moligand™ — Aladdin's line of ligands and bioactive small molecules. Use for receptor, pathway, and binding studies needing defined small-molecule tools.
    Out of Stock Item #: S614277
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    IUPAC Name
    2-(2-aminoethylamino)-4-[3-(trifluoromethyl)anilino]pyrimidine-5-carboxamide
    SMILES
    C1=CC(=CC(=C1)NC2=NC(=NC=C2C(=O)N)NCCN)C(F)(F)F
    InChIKey
    FQNFLNSVHWCZML-UHFFFAOYSA-N
    InChI
    1S/C14H15F3N6O/c15-14(16,17)8-2-1-3-9(6-8)22-12-10(11(19)24)7-21-13(23-12)20-5-4-18/h1-3,6-7H,4-5,18H2,(H2,19,24)(H2,20,21,22,23)
    Synonyms
    2-[(2-aminoethyl)amino]-4-{[3-(trifluoromethyl)phenyl]amino}pyrimidine-5-carboxamide | N16847 | SCHEMBL1222899 | DHY3...
  9. Src Inhibitor 3
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    Src Inhibitor 3
    CAS: 2380027-49-4 PubChem CID: 139600340 Formula: C34H32ClFN8O4 Molecular Weight: 671.12
    ≥98%
    Out of Stock Item #: S648046
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    Technical Identifiers
    IUPAC Name
    N-[3-chloro-4-[(6-methoxypyrazolo[1,5-a]pyridine-3-carbonyl)amino]phenyl]-1-[1-(3-cyano-3-methylbutanoyl)piperidin-4-yl]-5-fluoroindazole-3-carboxamidshow more
    SMILES
    CC(C)(CC(=O)N1CCC(CC1)N2C3=C(C=C(C=C3)F)C(=N2)C(=O)NC4=CC(=C(C=C4)NC(=O)C5=C6C=CC(=CN6N=C5)OC)Cl)C#N
    InChIKey
    LQQYARMJQBHKQQ-UHFFFAOYSA-N
    InChI
    1S/C34H32ClFN8O4/c1-34(2,19-37)16-30(45)42-12-10-22(11-13-42)44-29-8-4-20(36)14-24(29)31(41-44)33(47)39-21-5-7-27(26(35)15-21)40-32(46)25-17-38-43-18-show more
  10. Syk-IN-1
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    Syk-IN-1
    CAS: 1491150-77-6 PubChem CID: 72202597 Formula: C18H22N8O Molecular Weight: 366.42
    ≥99%
    Out of Stock Item #: S647457
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    IUPAC Name
    3-[[(1R,2S)-2-aminocyclohexyl]amino]-5-(1H-indol-7-ylamino)-1,2,4-triazine-6-carboxamide
    SMILES
    C1CCC(C(C1)N)NC2=NC(=C(N=N2)C(=O)N)NC3=CC=CC4=C3NC=C4
    InChIKey
    FPQNRXITKTZFMF-NWDGAFQWSA-N
    InChI
    1S/C18H22N8O/c19-11-5-1-2-6-12(11)23-18-24-17(15(16(20)27)25-26-18)22-13-7-3-4-10-8-9-21-14(10)13/h3-4,7-9,11-12,21H,1-2,5-6,19H2,(H2,20,27)(H2,22,23,show more
  12. Aloisine RP106
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    Aloisine RP106
    CAS: 496864-15-4 EC Number: 637-125-0 PubChem CID: 3641059 Formula: C16H17N3O
    Out of Stock Item #: A1425194
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    Technical Identifiers
    IUPAC Name
    7-butyl-6-(4-methoxyphenyl)-5H-pyrrolo[2,3-b]pyrazine
    SMILES
    CCCCC1=C(NC2=NC=CN=C12)C3=CC=C(C=C3)OC
    InChIKey
    WVMANZPBOBRWCB-UHFFFAOYSA-N
    InChI
    1S/C17H19N3O/c1-3-4-5-14-15(12-6-8-13(21-2)9-7-12)20-17-16(14)18-10-11-19-17/h6-11H,3-5H2,1-2H3,(H,19,20)
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