Determine the necessary mass, volume, or concentration for preparing a solution.
≥98% for sensitive chromatographic and analytical workflows requiring minimal baseline interference.
Store at 2-8°C,Protected from light Ships Wet ice Check lot-specific COA for exact specifications.
SDS, COA, datasheet, and spec sheet available for download. Lot-specific COA accessible via lot number lookup.
Cited in 32 peer-reviewed publications across chromatography, organic synthesis, and cross-coupling reactions.
| Pubchem Sid | 504758902 |
|---|---|
| Pubchem Sid Url | https://pubchem.ncbi.nlm.nih.gov/substance/504758902 |
| Canonical Smiles | CCNCC1=CC(=CC=C1)F |
| IUPAC Name | N-[(3-fluorophenyl)methyl]ethanamine |
| InChIKey | QAPAPLIQQTVEJZ-UHFFFAOYSA-N |
| INCHI | 1S/C9H12FN/c1-2-11-7-8-4-3-5-9(10)6-8/h3-6,11H,2,7H2,1H3 |
| Isomeric SMILES | CCNCC1=CC(=CC=C1)F |
| Molecular Weight | 153.2 |
| Reaxy-Rn | 2828967 |
| Reaxys-RN_link_address | https://www.reaxys.com/reaxys/secured/hopinto.do?context=S&query=IDE.XRN=2828967&ln= |
Comprehensive hazard, handling, storage, and regulatory compliance document.
Download SDS →Lot-specific quality data. Enter your lot number to retrieve the exact COA.
Look up COA →Full quality attributes and acceptance criteria for this grade.
View spec sheet →Taxonomy Tree
| Kingdom | Organic compounds |
|---|---|
| Superclass | Benzenoids |
| Class | Benzene and substituted derivatives |
| Subclass | Phenylmethylamines |
| Intermediate Tree Nodes | Not available |
| Direct Parent | Phenylmethylamines |
| Alternative Parents | Benzylamines Fluorobenzenes Aralkylamines Aryl fluorides Dialkylamines Organopnictogen compounds Organofluorides Hydrocarbon derivatives |
| Molecular Framework | Aromatic homomonocyclic compounds |
| Substituents | Benzylamine - Phenylmethylamine - Aralkylamine - Fluorobenzene - Halobenzene - Aryl fluoride - Aryl halide - Secondary aliphatic amine - Secondary amine - Organonitrogen compound - Amine - Hydrocarbon derivative - Organopnictogen compound - Organic nitrogen compound - Organohalogen compound - Organofluoride - Aromatic homomonocyclic compound |
| Description | This compound belongs to the class of organic compounds known as phenylmethylamines. These are compounds containing a phenylmethtylamine moiety, which consists of a phenyl group substituted by an methanamine. |
| External Descriptors | Not available |
| Sensitivity | Light sensitive |
|---|---|
| Molecular Weight | 153.200 g/mol |
| XLogP3 | 2.100 |
| Hydrogen Bond Donor Count | 1 |
| Hydrogen Bond Acceptor Count | 2 |
| Rotatable Bond Count | 3 |
| Exact Mass | 153.095 Da |
| Monoisotopic Mass | 153.095 Da |
| Topological Polar Surface Area | 12.000 Ų |
| Heavy Atom Count | 11 |
| Formal Charge | 0 |
| Complexity | 106.000 |
| Isotope Atom Count | 0 |
| Defined Atom Stereocenter Count | 0 |
| Undefined Atom Stereocenter Count | 0 |
| Defined Bond Stereocenter Count | 0 |
| Undefined Bond Stereocenter Count | 0 |
| The total count of all stereochemical bonds | 0 |
| Covalently-Bonded Unit Count | 1 |
| 1. Hongshuai Lv, Weiping Jia, Li Yang, Peng Dong, Jiaojiao Liu, Si Wang, Xiaohai Li, Jinghua Hu, Ling Zhao, Yikang Shi. (2023) Influence of unsaturated fatty acids on the antitumor activity of polymeric conjugates grafted with cabazitaxel against prostate cancer. BIOMEDICINE & PHARMACOTHERAPY, [PMID:37989031] [10.1016/j.biopha.2023.115902] |
| 2. Yubo Jia, Zhuosen He, Yucui Hou, He Li, Shuhang Ren, Weize Wu. (2023) Adsorption and transfer behaviors of hydrogen on Fe1-xS catalysts for direct coal liquefaction. FUEL, [PMID:] [10.1016/j.fuel.2023.128893] |
| 3. Jia Jing, Chen Wenping, Xu Long, Wang Xuewen, Li Min, Wang Bin, Huang Xiangyu, Wang Tao, Chen Yang, Li Mengdie, Tian Dan, Zhuang Junyang, Lin Xinhua, Li Ning. (2023) Codelivery of dihydroartemisinin and chlorin e6 by copolymer nanoparticles enables boosting photodynamic therapy of breast cancer with low-power irradiation. Regenerative Biomaterials, [PMID:37250978] [10.1093/rb/rbad048] |
| 4. Lei Zhang, Peng Shi, Lin Zhang, Yajun Wang, Jilin Xu, Xiaojun Yan, Kai Liao. (2023) Molecular Characterization and Expression Response of Ghrelin, GLP-1 and PYY to Fasting, Dietary Lipid, and Fatty Acids in Silver Pomfret (Pampus argenteus). Fishes, 8 (3): (170). [PMID:] [10.3390/fishes8030170] |
| 5. Fangqin Fu, Wenhao Wang, Linjing Wu, Wenhua Wang, Zhengwei Huang, Ying Huang, Chuanbin Wu, Xin Pan. (2023) Inhalable Biomineralized Liposomes for Cyclic Ca2+-Burst-Centered Endoplasmic Reticulum Stress Enhanced Lung Cancer Ferroptosis Therapy. ACS Nano, [PMID:36883602] [10.1021/acsnano.2c10830] |
| 6. Peng Dong, Hongshuai Lv, Weiping Jia, Jiaojiao Liu, Si Wang, Xiaohai Li, Jinghua Hu, Ling Zhao, Yikang Shi. (2022) Polysaccharide dextran-based conjugate for selective co-delivery of two synergistic drugs docetaxel and docosahexaenoic acid to tumor cells. DRUG DELIVERY, [PMID:36458324] [10.1080/10717544.2022.2152133] |
| 7. Jiaojiao Liu, Naining Zhang, Jiaan Wu, Peng Dong, Hongshuai Lv, Qi Wang, Shenxu Wang, Haotong Yang, Si Wang, Xiaohai Li, Jinghua Hu, Anny Wang, Daisy J Li, Yikang Shi. (2022) A Novel Dextran-Based Dual Drug Conjugate Targeted Tumors with High Biodistribution Ratio of Tumors to Normal Tissues. International Journal of Nanomedicine, [PMID:36262192] [10.2147/IJN.S379758] |
| 8. Jie Cheng, Yuling Li, Yunjun Wang, Jing Zhang, Tuanqi Sun, Li Zhang, Yinlong Guo. (2022) Quaterization Derivatization with Bis(Pyridine) Iodine Tetrafluoroboride: High-Sensitivity Mass Spectrometric Analysis of Unsaturated Fatty Acids in Human Thyroid Tissues. ANALYTICAL CHEMISTRY, [PMID:35916214] [10.1021/acs.analchem.2c01519] |
| 9. Shenxu Wang, Jiaojiao Liu, Hongshuai Lv, Xiaoyan Huang, Peng Dong, Qi Wang, Haotong Yang, Si Wang, Xiaohai Li, Jinghua Hu, Dandan Wang, Shengnan Cao, Liangyu Xie, Yikang Shi. (2022) Complete regression of xenografted breast tumors by dextran-based dual drug conjugates containing paclitaxel and docosahexaenoic acid. EUROPEAN JOURNAL OF MEDICINAL CHEMISTRY, [PMID:35779290] [10.1016/j.ejmech.2022.114567] |
| 10. Peng Dong, Jiaojiao Liu, Hongshuai Lv, Jiaan Wu, Naining Zhang, Si Wang, Xiaohai Li, Jinghua Hu, Anny Wang, Daisy J. Li, Dandan Wang, Shengnan Cao, Liangyu Xie, Yikang Shi. (2022) The enhanced antitumor activity of the polymeric conjugate covalently coupled with docetaxel and docosahexaenoic acid. Biomaterials Science, 10 (13): (3454-3465). [PMID:35647736] [10.1039/D2BM00337F] |
| 11. Dan Cao, Min Liu, Yung-Chih Su, Zehui Yang, Wentao Bi, David Da Yong Chen. (2022) Adsorption behavior of anthraquinones in deep eutectic solvent on polyester fiber and its application. Sustainable Chemistry and Pharmacy, [PMID:] [10.1016/j.scp.2022.100680] |
| 12. Tongxi Li, Yifan Chen, Peng Tan, Hao Shi, Zhiwei Huang, Tianying Cai, Yonglang Cheng, Yichao Du, Wenguang Fu. (2022) Dihydroartemisinin alleviates steatosis and inflammation in nonalcoholic steatohepatitis by decreasing endoplasmic reticulum stress and oxidative stress. BIOORGANIC CHEMISTRY, [PMID:35338970] [10.1016/j.bioorg.2022.105737] |
| 13. Tao Shen, Zhenwen Hu, Qingya Liu, Tingyu Lei, Zhenyu Liu. (2021) A method to evaluate hydrogen donation ability of hydrogen-storage solvent in hydrogenation process by radical-precursor compounds. FUEL, [PMID:] [10.1016/j.fuel.2021.122741] |
| 14. Jianqing Peng, Qin Wang, Jia Zhou, Shuli Zhao, Pan Di, Yan Chen, Ling Tao, Qianming Du, Xiangchun Shen, Yi Chen. (2021) Targeted Lipid Nanoparticles Encapsulating Dihydroartemisinin and Chloroquine Phosphate for Suppressing the Proliferation and Liver Metastasis of Colorectal Cancer.. Frontiers in Pharmacology, [PMID:34690764] [10.3389/fphar.2021.720777] |
| 15. Zhiwei Wang, Mingxing Li, Yuanfeng Liu, Zhentao Qiao, Tao Bai, Ling Yang, Bo Liu. (2021) Dihydroartemisinin triggers ferroptosis in primary liver cancer cells by promoting and unfolded protein response‑induced upregulation of CHAC1 expression. ONCOLOGY REPORTS, 46 (5): (1-14). [PMID:34558645] [10.3892/or.2021.8191] |
| 16. Qianyu Chen, Yayun Zhang, Jianhua Li, Guanyong Su, Qi Chen, Zhen Ding, Hong Sun. (2021) Serum concentrations of neonicotinoids, and their associations with lipid molecules of the general residents in Wuxi City, Eastern China. JOURNAL OF HAZARDOUS MATERIALS, [PMID:33581671] [10.1016/j.jhazmat.2021.125235] |
| 17. Yanyan Liu, Yanhong Yang, Yuting Lei, Lanxiang Yang, Xueying Zhang, Jian Yuan, Zili Lei. (2020) Effects of dihydroartemisinin on the gut microbiome of mice. Molecular Medicine Reports, 22 (2): (707-714). [PMID:32468008] [10.3892/mmr.2020.11165] |
| 18. Zili Lei, Yanhong Yang, Shaomin Liu, Yuting Lei, Lanxiang Yang, Xueying Zhang, Wanwan Liu, Huijuan Wu, Changyuan Yang, Jiao Guo. (2020) Dihydroartemisinin ameliorates dextran sulfate sodium induced inflammatory bowel diseases in mice. BIOORGANIC CHEMISTRY, [PMID:32450383] [10.1016/j.bioorg.2020.103915] |
| 19. Xie-an Yu, Mi Lu, Yingping Luo, Yiting Hu, Ying Zhang, Zhiming Xu, Shuaishuai Gong, Yunhao Wu, Xiao-Nan Ma, Bo-Yang Yu, Jiangwei Tian. (2020) A cancer-specific activatable theranostic nanodrug for enhanced therapeutic efficacy via amplification of oxidative stress. Theranostics, [PMID:31903126] [10.7150/thno.39412] |
| 20. Qi Zhao, Jian Li, Yang Xu, Dandan Lv, Kanyasiri Rakariyatham, Dayong Zhou. (2019) Rapid extraction of free fatty acids from edible oil after accelerated storage based on amino-modified magnetic silica nanospheres. Analytical Methods, 11 (35): (4520-4527). [PMID:] [10.1039/C9AY01082C] |
| 21. Deyang Li, Hongkai Xie, Zhongyuan Liu, Ao Li, Jiaxuan Li, Bing Liu, Xiaoyang Liu, Dayong Zhou. (2019) Shelf life prediction and changes in lipid profiles of dried shrimp (Penaeus vannamei) during accelerated storage. FOOD CHEMISTRY, [PMID:31253340] [10.1016/j.foodchem.2019.124951] |
| 22. Hongkai Xie, Dayong Zhou, Xiaopei Hu, Zhongyuan Liu, Liang Song, Beiwei Zhu. (2018) Changes in Lipid Profiles of Dried Clams (Mactra chinensis Philippi and Ruditapes philippinarum) during Accelerated Storage and Prediction of Shelf Life. JOURNAL OF AGRICULTURAL AND FOOD CHEMISTRY, [PMID:29965751] [10.1021/acs.jafc.8b03047] |
| 23. Yanzhi Yu, Yujun Zhang, Xiaojing Hua, Yuanan Lu, Xueqin Liu. (2024) Cholic acid-based inhibition of SVCV replication by modulating polyunsaturated fatty acid content. AQUACULTURE, [PMID:] [10.1016/j.aquaculture.2024.741712] |
| 24. Peishan Qiu, Ying Chang, Xiaoyu Chen, Shaoqi Wang, Haihang Nie, Yuntian Hong, Meng Zhang, Haizhou Wang, Cong Xiao, Yuhua Chen, Lan Liu, Qiu Zhao. (2024) Dihydroartemisinin Modulates Enteric Glial Cell Heterogeneity to Alleviate Colitis. Advanced Science, [PMID:38992955] [10.1002/advs.202403461] |
| 25. Wu Linjing, Wang Wenhao, Guo Mengqin, Fu Fangqin, Wang Wenhua, Sung Tszching, Zhang Meihong, Zhong Ziqiao, Wu Chuanbin, Pan Xin, Huang Zhengwei. (2024) Inhalable iron redox cycling powered nanoreactor for amplified ferroptosis-apoptosis synergetic therapy of lung cancer. Nano Research, [PMID:] [10.1007/s12274-024-6455-2] |
| 26. Dan Wei, Jianliang Li, Ming Guo, Jingjing Xu, Qiao Deng, Xu Wang. (2024) Rational selection of 4,4′,4″-(1,3,5-triazine-2,4,6-triyl) trianiline-based covalent organic framework as adsorbent for effective co-extraction of aflatoxins, zearalenone and its metabolites from food and biological samples. FOOD CHEMISTRY, [PMID:39243614] [10.1016/j.foodchem.2024.141013] |
| 27. Beibei Zhang, Hao Liu, Yifei Wang, Yong Zhang. (2024) ROS-Responsive and Self-Catalytic Nanocarriers for a Combination of Chemotherapy and Reinforced Ferroptosis against Breast Cancer. ACS Biomaterials Science & Engineering, [PMID:39262329] [10.1021/acsbiomaterials.4c01233] |
| 28. Wen Zhang, Yang Liu, Yu Wu, Zhicun Wang, Xiyu Liu, Qinsheng Hu, Li Yang, Cheng Hu, Yunbing Wang. (2025) ROS-Triggered Biomimetic Hydrogel Soft Scaffold for Ischemic Stroke Repair. BIOMATERIALS, [PMID:40023927] [10.1016/j.biomaterials.2025.123217] |
| 29. Zhe Jiao, Xiudong Shi, Xiaolin Zhang, Xiaofang Zhao, Yueting Wang, Feng Xu, Jing Zhang. (2025) Eu-COF-based fluorescent and portable detection of acetone in exhaled breath. Analytical Methods, [PMID:40271919] [10.1039/D5AY00230C] |
| 30. Zixin Zhu, Qingyun Xie, Yiwan Sun, Fan Yan, Xiao Kang, Przemysław Zalewski, Xue Gou. (2025) Electrically controlled on-demand wound therapy based on real-time pH monitoring. CHEMICAL ENGINEERING JOURNAL, [PMID:] [10.1016/j.cej.2025.162522] |
| 31. Jingyu Li, Bing Fang, Yao Wu, Yuhang Sun, Yue Liu, haina gao, Ming Zhang. (2025) Investigating the Neuroprotective Effects of Polyunsaturated Fatty Acids in Egg Yolk Phospholipids on Oxidative Damage in HT22 Cells. Food & Function, [PMID:40341910] [10.1039/D5FO00833F] |
| 32. Wang Bao, Fu Junpeng, Qian Jian, Wei Yuang, Bao Meiling, Miao Haoqi, Zhao Xinzhe, Shao Kezheng, Song Yuan, Tan Ruoyun, Li Jie, Shao Pengfei. (2026) SREBP1-activated lipid metabolism drives ferroptosis and progression of clear cell renal cell carcinoma. Science China-Life Sciences, [PMID:41706270] [10.1007/s11427-025-3237-4] |