N-Octanoyl-DL-homoserine lactone - ≥97%(HPLC) , CAS No.106983-30-6

CAS: 106983-30-6 Cat. No.: N464432 Molecular Weight: 227.3 Beilstein Registry Number: 1642628

GRADE & PURITY ≥97%(HPLC)

Synonyms

SCHEMBL3745514 | N-Octanoyl-DL-homoserine lactone | DTXSID801046077 | N-Octanoyl-DL-homoserine lactone, >=97.0% (HPLC) | E0C11178-D3A4-4DD0-8A56-4120B3073C2B | Homoserine lactone, N-octanoyl- | N-Octanyol-DL-homoserine lactone | N-(2-oxooxolan-3-yl)octana

Storage

Store at -20°C

Shipped In

Ice chest + Ice pads

Overview

Description

Application test: Induces violacein expression in aChromobacterium violaceummutant usually not able to produce homoserine lactones.

Specifications

Synonyms

SCHEMBL3745514 | N-Octanoyl-DL-homoserine lactone | DTXSID801046077 | N-Octanoyl-DL-homoserine lactone, >=97.0% (HPLC) | E0C11178-D3A4-4DD0-8A56-4120B3073C2B | Homoserine lactone, N-octanoyl- | N-Octanyol-DL-homoserine lactone | N-(2-oxooxolan-3-yl)octana

Specifications & Purity

≥97%(HPLC)

Biochemical and Physiological Mechanisms

N-Octanoyl-DL-homoserine lactone is a member of N-acyl-homoserine lactone family. N-acylhomoserine lactones (AHL) regulate gene expression in gram-negative bacteria, such asEcherichiaandSalmonellaare involved in quorum sensing, cell to cell commu

Storage

Store at -20°C

Shipped In

Ice chest + Ice pads

This product requires cold chain shipping. Ground and other economy services are not available.

Action Type

INHIBITOR

Purity

≥97%(HPLC)

Names and Identifiers

• Pubchem Sid: 504762574
• Pubchem Sid Url: https://pubchem.ncbi.nlm.nih.gov/substance/504762574
• Canonical Smiles: CCCCCCCC(=O)NC1CCOC1=O
• IUPAC Name: N-(2-oxooxolan-3-yl)octanamide
• InChIKey: JKEJEOJPJVRHMQ-UHFFFAOYSA-N
• INCHI: 1S/C12H21NO3/c1-2-3-4-5-6-7-11(14)13-10-8-9-16-12(10)15/h10H,2-9H2,1H3,(H,13,14)
• Isomeric SMILES: CCCCCCCC(=O)NC1CCOC1=O
• Molecular Weight: 227.3
• Beilstein: 1642628
• Reaxy-Rn: 1642628
• Reaxys-RN_link_address: https://www.reaxys.com/reaxys/secured/hopinto.do?context=S&query=IDE.XRN=1642628&ln=

Taxonomic Classification

Taxonomy Tree

• Kingdom Organic compounds
  • Superclass Organic acids and derivatives
    • Class Carboxylic acids and derivatives
      • Subclass Amino acids, peptides, and analogues
        • Level5 Amino acids and derivatives
          • Level6 Alpha amino acids and derivatives
            • Level7 N-acyl-alpha amino acids and derivatives

• Kingdom: Organic compounds
• Superclass: Organic acids and derivatives
• Class: Carboxylic acids and derivatives
• Subclass: Amino acids, peptides, and analogues
• Intermediate Tree Nodes: Amino acids and derivatives - Alpha amino acids and derivatives
• Direct Parent: N-acyl-alpha amino acids and derivatives
• Alternative Parents: Alpha amino acid esters Acyl homoserine lactones N-acyl amines Gamma butyrolactones Oxolanes Secondary carboxylic acid amides Carboxylic acid esters Oxacyclic compounds Monocarboxylic acids and derivatives Organopnictogen compounds Organonitrogen compounds Organic oxides Hydrocarbon derivatives Carbonyl compounds
• Molecular Framework: Aliphatic heteromonocyclic compounds
• Substituents: Alpha-amino acid ester - N-acyl-alpha amino acid or derivatives - Acyl-homoserine lactone - Fatty amide - Gamma butyrolactone - Fatty acyl - N-acyl-amine - Oxolane - Carboxamide group - Carboxylic acid ester - Lactone - Secondary carboxylic acid amide - Oxacycle - Organoheterocyclic compound - Monocarboxylic acid or derivatives - Organic nitrogen compound - Hydrocarbon derivative - Organic oxide - Organopnictogen compound - Carbonyl group - Organic oxygen compound - Organooxygen compound - Organonitrogen compound - Aliphatic heteromonocyclic compound
• Description: This compound belongs to the class of organic compounds known as n-acyl-alpha amino acids and derivatives. These are compounds containing an alpha amino acid (or a derivative thereof) which bears an acyl group at its terminal nitrogen atom.
• External Descriptors: an acyl-homoserine lactone

Data sources

1. Djoumbou Feunang Y, Eisner R, Knox C, Chepelev L, Hastings J, Owen G, Fahy E, Steinbeck C, Subramanian S, Bolton E, Greiner R, and Wishart DS. ClassyFire: Automated Chemical Classification With A Comprehensive, Computable Taxonomy. Journal of Cheminformatics, 2016, 8:61.

DOI: 10.1186/s13321-016-0174-y

Chemical and Physical Properties

• Sensitivity: Moisture sensitive
• Flash Point(°F): Not applicable
• Flash Point(°C): Not applicable
• Molecular Weight: 227.300 g/mol
• XLogP3: 2.600
• Hydrogen Bond Donor Count: 1
• Hydrogen Bond Acceptor Count: 3
• Rotatable Bond Count: 7
• Exact Mass: 227.152 Da
• Monoisotopic Mass: 227.152 Da
• Topological Polar Surface Area: 55.400 Ų
• Heavy Atom Count: 16
• Formal Charge: 0
• Complexity: 240.000
• Isotope Atom Count: 0
• Defined Atom Stereocenter Count: 0
• Undefined Atom Stereocenter Count: 1
• Defined Bond Stereocenter Count: 0
• Undefined Bond Stereocenter Count: 0
• The total count of all stereochemical bonds: 0
• Covalently-Bonded Unit Count: 1

References

1. Qian Feng, Laiwei Luo, Xindi Chen, Kaijie Zhang, Fang Fang, Zhaoxia Xue, Chao Li, Jiashun Cao, Jingyang Luo.  (2021)  Facilitating biofilm formation of Pseudomonas aeruginosa via exogenous N-Acy-L-homoserine lactones stimulation: Regulation on the bacterial motility, adhesive ability and metabolic activity.  BIORESOURCE TECHNOLOGY,      [PMID:34411944] [10.1016/j.biortech.2021.125727]

2. Keyang Jiang, Xiao Yang, Qian Gao, Junxia Ni, Jinhu Feng, Di Wu, Xuelian Zou, Li Hu, Xi Liu, Zhaoping Song, Zhiwei Wang.  (2024)  Exogenous signaling molecules N-acyl-homoserine lactones promotes the reconstruction of sludge particles after impact with highly concentrated urea-formaldehyde resin microplastics.  JOURNAL OF ENVIRONMENTAL MANAGEMENT,      [PMID:39504669] [10.1016/j.jenvman.2024.123179]

3. Meng Yuan, Guotao Chen, Zhiqi Zhang, Jinghui Wang, Yan Zhao, Guanghong Xie, Yin Jiang, Yuan Ren.  (2026)  Yarrowia lipolytica extracellular metabolites induce microbial signaling and interactions to enhance chlorinated hydrocarbon degradation in soil.  Journal of Environmental Chemical Engineering,  14  (1): (121100).  [PMID:] [10.1016/j.jece.2026.121100]