N-[(S)-alpha-Ethylbenzyl]-2-phenylquinoline-4-carboxamide , MAP kinase p38 alpha inhibitor, CAS No.1760285, MAP kinase p38 alpha inhibitor

CAS: 1760285 Cat. No.: N670991 Molecular Weight: 366.5
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Synonyms
CHEMBL9960 | 2-Phenyl-quinoline-4-carboxylic acid ((S)-1-phenyl-propyl)-amide | AZD 7624 | SCHEMBL6447341 | (s)-n-(1-phenylpropyl)-2-phenylquinoline-4-carboxamide | MLE-4901;AZD2624;AZD4901 | BDBM50051294
Storage
Room temperature
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Size
Status
Price
Qty
1mg
N670991-1mg
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$999.90
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Why this grade

for sensitive chromatographic and analytical workflows requiring minimal baseline interference.

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Storage & shipping

Room temperature Ships Check lot-specific COA for exact specifications.

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Quality documents

SDS, COA, datasheet, and spec sheet available for download. Lot-specific COA accessible via lot number lookup.

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Literature proof

Cited in 0 peer-reviewed publications across chromatography, organic synthesis, and cross-coupling reactions.

Specifications

Synonyms
CHEMBL9960 | 2-Phenyl-quinoline-4-carboxylic acid ((S)-1-phenyl-propyl)-amide | AZD 7624 | SCHEMBL6447341 | (s)-n-(1-phenylpropyl)-2-phenylquinoline-4-carboxamide | MLE-4901;AZD2624;AZD4901 | BDBM50051294
Storage
Room temperature
Action Type
INHIBITOR
Mechanism of action
MAP kinase p38 alpha inhibitor
Product Properties
ALogP5.6
Names and Identifiers
Canonical SmilesCCC(C1=CC=CC=C1)NC(=O)C2=CC(=NC3=CC=CC=C32)C4=CC=CC=C4
IUPAC Name2-phenyl-N-[(1S)-1-phenylpropyl]quinoline-4-carboxamide
InChIKeyMXNGYQJJYRVGGJ-QFIPXVFZSA-N
INCHI1S/C25H22N2O/c1-2-22(18-11-5-3-6-12-18)27-25(28)21-17-24(19-13-7-4-8-14-19)26-23-16-10-9-15-20(21)23/h3-17,22H,2H2,1H3,(H,27,28)/t22-/m0/s1
Isomeric SMILES CC[C@@H](C1=CC=CC=C1)NC(=O)C2=CC(=NC3=CC=CC=C32)C4=CC=CC=C4
Molecular Weight 366.5
Reaxy-Rn 7545667
Reaxys-RN_link_address https://www.reaxys.com/reaxys/secured/hopinto.do?context=S&query=IDE.XRN=7545667&ln=

Documentation

📋 Safety Data Sheet (SDS)

Comprehensive hazard, handling, storage, and regulatory compliance document.

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✅ Certificate of Analysis (COA)

Lot-specific quality data. Enter your lot number to retrieve the exact COA.

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📊 Datasheet

Quick-reference summary of product specifications and applications.

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🔬 Specification Sheet

Full quality attributes and acceptance criteria for this grade.

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Advanced Data

Taxonomic Classification

Taxonomy Tree

KingdomOrganic compounds
SuperclassOrganoheterocyclic compounds
ClassQuinolines and derivatives
SubclassPhenylquinolines
Intermediate Tree Nodes Not available
Direct ParentPhenylquinolines
Alternative Parents Quinoline carboxamides  Phenylpyridines  Pyridinecarboxylic acids and derivatives  Phenylpropanes  Heteroaromatic compounds  Secondary carboxylic acid amides  Azacyclic compounds  Organopnictogen compounds  Organooxygen compounds  Organonitrogen compounds  Organic oxides  Hydrocarbon derivatives  
Molecular FrameworkAromatic heteropolycyclic compounds
Substituents Phenylquinoline - Quinoline-4-carboxamide - 2-phenylpyridine - Phenylpropane - Pyridine carboxylic acid or derivatives - Monocyclic benzene moiety - Pyridine - Benzenoid - Heteroaromatic compound - Carboxamide group - Secondary carboxylic acid amide - Azacycle - Carboxylic acid derivative - Hydrocarbon derivative - Organic oxide - Organopnictogen compound - Organic oxygen compound - Organooxygen compound - Organonitrogen compound - Organic nitrogen compound - Aromatic heteropolycyclic compound
DescriptionThis compound belongs to the class of organic compounds known as phenylquinolines. These are heterocyclic compounds containing a quinoline moiety substituted with a phenyl group.
External Descriptors Not available
3D Structure
Interactive Chemical Structure Model





Associated Targets(Human)
TACR3 Tchem Neuromedin-K receptor (1 Activities)
Activity TypeActivity Value -log(M)Mechanism of ActionActivity ReferencePublications (PubMed IDs)
TACR1 Tclin Neurokinin 1 receptor (6273 Activities)
Activity TypeRelationActivity valueUnitsAction TypeJournalPubMed IddoiAssay Aladdin ID
TACR2 Tchem Neurokinin 2 receptor (3341 Activities)
Activity TypeRelationActivity valueUnitsAction TypeJournalPubMed IddoiAssay Aladdin ID
TACR3 Tchem Neurokinin 3 receptor (1696 Activities)
Activity TypeRelationActivity valueUnitsAction TypeJournalPubMed IddoiAssay Aladdin ID
Mechanisms of Action
Certificates(CoA,COO,BSE/TSE and Analysis Chart)
C of A & Other Certificates(BSE/TSE, COO):
Analytical Chart:
Solution Calculators
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