Determine the necessary mass, volume, or concentration for preparing a solution.
| Activity Type | Activity Value -log(M) | Mechanism of Action | Activity Reference | Publications (PubMed IDs) |
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224,000+ research products · Triple ISO certified · COA & SDS available for every product · Same-day shipping on in-stock items
Why this grade
Moligand™, ≥98% Moligand™ for sensitive chromatographic and analytical workflows requiring minimal baseline interference.
Storage & shipping
Store at -20°C Ships Ice chest + Ice pads Check lot-specific COA for exact specifications.
Quality documents
SDS, COA, datasheet, and spec sheet available for download. Lot-specific COA accessible via lot number lookup.
Literature proof
Cited in 2 peer-reviewed publications across chromatography, organic synthesis, and cross-coupling reactions.
Specifications
Synonyms
N-Cyclohexyladenosine | CHA
Specifications & Purity
Moligand™, ≥98%
Biochemical and Physiological Mechanisms
Selective A 1 receptor agonist (EC 50 = 8.2 nM). Adenosine analogue; exerts anticonvulsant effects and protects against neuronal death.
Storage
Store at -20°C
Shipped In
Ice chest + Ice pads
This product requires cold chain shipping. Ground and other economy services are not available.
Grade
Moligand™
Action Type
AGONIST
Mechanism of action
Agonist of A 1 receptor;Agonist of A 2A receptor;Agonist of A 2B receptor;Agonist of A 3 receptor
Note
Wherever possible, you should prepare and use solutions on the same day. However, if you need to make up stock solutions in advance, we recommend that you store the solution as aliquots in tightly sealed vials at -20°C. Generally, these will be useable for up to one month. Before use, and prior to opening the vial we recommend that you allow your product to equilibrate to room temperature for at least 1 hour. Need more advice on solubility, usage and handling? Please visit our frequently asked questions (FAQ) page for more details.
Purity
≥98%
Names and Identifiers
| Canonical Smiles | C1CCC(CC1)NC2=C3C(=NC=N2)N(C=N3)C4C(C(C(O4)CO)O)O |
|---|---|
| IUPAC Name | (2R,3R,4S,5R)-2-[6-(cyclohexylamino)purin-9-yl]-5-(hydroxymethyl)oxolane-3,4-diol |
| InChIKey | SZBULDQSDUXAPJ-XNIJJKJLSA-N |
| INCHI | 1S/C16H23N5O4/c22-6-10-12(23)13(24)16(25-10)21-8-19-11-14(17-7-18-15(11)21)20-9-4-2-1-3-5-9/h7-10,12-13,16,22-24H,1-6H2,(H,17,18,20)/t10-,12-,13-,16-/m1/s1 |
| Isomeric SMILES | C1CCC(CC1)NC2=C3C(=NC=N2)N(C=N3)[C@H]4[C@@H]([C@@H]([C@H](O4)CO)O)O |
| WGK Germany | 3 |
| Molecular Weight | 349.38 |
| Reaxy-Rn | 24717370 |
| Reaxys-RN_link_address | https://www.reaxys.com/reaxys/secured/hopinto.do?context=S&query=IDE.XRN=24717370&ln= |
Documentation
📋 Safety Data Sheet (SDS)
Comprehensive hazard, handling, storage, and regulatory compliance document.
Download SDS →✅ Certificate of Analysis (COA)
Lot-specific quality data. Enter your lot number to retrieve the exact COA.
Look up COA →🔬 Specification Sheet
Full quality attributes and acceptance criteria for this grade.
View spec sheet →Advanced Data
Taxonomic Classification
Taxonomy Tree
- Kingdom Organic compounds
- Superclass Nucleosides, nucleotides, and analogues
- Class Purine nucleosides
- Superclass Nucleosides, nucleotides, and analogues
| Kingdom | Organic compounds |
|---|---|
| Superclass | Nucleosides, nucleotides, and analogues |
| Class | Purine nucleosides |
| Subclass | Not available |
| Intermediate Tree Nodes | Not available |
| Direct Parent | Purine nucleosides |
| Alternative Parents | Glycosylamines 6-alkylaminopurines Pentoses Aminopyrimidines and derivatives N-substituted imidazoles Imidolactams Oxolanes Heteroaromatic compounds Secondary alcohols Oxacyclic compounds Azacyclic compounds Primary alcohols Hydrocarbon derivatives Amines |
| Molecular Framework | Aromatic heteropolycyclic compounds |
| Substituents | Purine nucleoside - Glycosyl compound - N-glycosyl compound - 6-alkylaminopurine - 6-aminopurine - Pentose monosaccharide - Purine - Imidazopyrimidine - Aminopyrimidine - Imidolactam - Pyrimidine - N-substituted imidazole - Monosaccharide - Heteroaromatic compound - Oxolane - Azole - Imidazole - Secondary alcohol - Organoheterocyclic compound - Oxacycle - Azacycle - Hydrocarbon derivative - Organonitrogen compound - Organic oxygen compound - Organic nitrogen compound - Organooxygen compound - Alcohol - Amine - Primary alcohol - Aromatic heteropolycyclic compound |
| Description | This compound belongs to the class of organic compounds known as purine nucleosides. These are compounds comprising a purine base attached to a ribosyl or deoxyribosyl moiety. |
| External Descriptors | Not available |
3D Structure
Interactive Chemical Structure Model
Associated Targets(Human)
ADORA2A Tclin Adenosine receptor A2a (2 Activities)
ADORA2B Tclin Adenosine receptor A2b (1 Activities)
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ADORA1 Tclin Adenosine receptor A1 (1 Activities)
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ADORA3 Tchem Adenosine receptor A3 (2 Activities)
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DRD1 Tclin Dopamine D1 receptor (9720 Activities)
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ADORA1 Tclin Adenosine A1 receptor (17603 Activities)
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ADRA1A Tclin Alpha-1a adrenergic receptor (8359 Activities)
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ADORA2A Tclin Adenosine A2a receptor (16305 Activities)
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ADORA2B Tclin Adenosine A2b receptor (7672 Activities)
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ADORA3 Tchem Adenosine A3 receptor (15931 Activities)
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ALB Tchem Serum albumin (2651 Activities)
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ARSA Tbio Cerebroside-sulfatase (655 Activities)
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Caco-2 (12174 Activities)
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HT-29 (80576 Activities)
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K562 (73714 Activities)
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MCF7 (126967 Activities)
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HEK293 (82097 Activities)
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TDP1 Tchem Tyrosyl-DNA phosphodiesterase 1 (345557 Activities)
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SMN1 Tchem Survival motor neuron protein (34246 Activities)
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PMP22 Tbio Peripheral myelin protein 22 (699 Activities)
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ATAD5 Tbio ATPase family AAA domain-containing protein 5 (122566 Activities)
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RUNX1 Tbio Runt-related transcription factor 1/Core-binding factor subunit beta (7867 Activities)
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PGK1 Tchem Phosphoglycerate kinase (287 Activities)
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ADORA1 Tclin Adenosine receptor (26 Activities)
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Associated Targets(non-human)
Rattus norvegicus (775804 Activities)
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pfk 6-phospho-1-fructokinase (7870 Activities)
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Txnrd1 Thioredoxin reductase 1, cytoplasmic (45279 Activities)
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Adora2b Adenosine A2 receptor (1828 Activities)
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Adora2b Adenosine receptors; A1 & A2 (886 Activities)
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Adora1 Adenosine receptors; A1 & A2a (368 Activities)
| Activity Type | Relation | Activity value | Units | Action Type | Journal | PubMed Id | doi | Assay Aladdin ID |
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Mechanisms of Action
Certificates（CoA,COO,BSE/TSE and Analysis Chart)
C of A & Other Certificates(BSE/TSE, COO):
Analytical Chart:
Find and download the COA for your product by matching the lot number on the packaging.
| Lot Number | Certificate Type | Date | Item |
|---|---|---|---|
 B2423418 | Certificate of Analysis | Jan 12, 2024 | N169925 |
| B2423419 | Certificate of Analysis | Jan 12, 2024 | N169925 |
| B2423420 | Certificate of Analysis | Jan 12, 2024 | N169925 |
| B2423421 | Certificate of Analysis | Jan 12, 2024 | N169925 |
| B2423422 | Certificate of Analysis | Jan 12, 2024 | N169925 |
| B2423423 | Certificate of Analysis | Jan 12, 2024 | N169925 |
Chemical and Physical Properties
| Sensitivity | Light sensitive; Moisture sensitive; Heat sensitive |
|---|---|
| Molecular Weight | 349.380 g/mol |
| XLogP3 | 1.400 |
| Hydrogen Bond Donor Count | 4 |
| Hydrogen Bond Acceptor Count | 8 |
| Rotatable Bond Count | 4 |
| Exact Mass | 349.175 Da |
| Monoisotopic Mass | 349.175 Da |
| Topological Polar Surface Area | 126.000 Ų |
| Heavy Atom Count | 25 |
| Formal Charge | 0 |
| Complexity | 452.000 |
| Isotope Atom Count | 0 |
| Defined Atom Stereocenter Count | 4 |
| Undefined Atom Stereocenter Count | 0 |
| Defined Bond Stereocenter Count | 0 |
| Undefined Bond Stereocenter Count | 0 |
| The total count of all stereochemical bonds | 0 |
| Covalently-Bonded Unit Count | 1 |
Citations of This Product
References
| 1. Qiulan Liu, Xiaoqin Zou, Yang Yi, Ying Sun, Hongxun Wang, Xueyu Jiang, Kaidi Peng. (2023) Physicochemical and Functional Changes in Lotus Root Polysaccharide Associated with Noncovalent Binding of Polyphenols. Foods, 12 (5): (1049). [PMID:36900568] [10.3390/foods12051049] |
| 2. Yu-Dong Shan, Song-Hai Wu, Yu-Le Wang, Cong Wang, Shao-Qi Zhi, Yong Liu, Xu Han. (2023) Selective Oxidation of Cyclohexane to Cyclohexanol/Cyclohexanone by Surface Peroxo Species on Cu-Mesoporous TiO2. INORGANIC CHEMISTRY, [PMID:36916853] [10.1021/acs.inorgchem.2c04196] |
Solution Calculators
Reviews
Customer Reviews
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