Norlaudanosine Hydrochloride - ≥98% , CAS No.6429-04-5

CAS: 6429-04-5 Cat. No.: N120346 Molecular Weight: 379.88 EC Number: 229-213-9

GRADE & PURITY ≥98%

Synonyms

N0918 | (2S)-1-N-BOC-2-ISOPROPYLPIPERAZINE | 1-[(3,4-dimethoxyphenyl)methyl]-6,7-dimethoxy-1,2,3,4-tetrahydroisoquinoline hydrochloride | 1-(3,4-Dimethoxybenzyl)-6,7-dimethoxy-1,2,3,4-tetrahydroisoquinolineHydrochloride | HY-N0137 | Norlaudanosine HCl | 1

Storage

Store at 2-8°C

Shipped In

Wet ice

Specifications

Synonyms

N0918 | (2S)-1-N-BOC-2-ISOPROPYLPIPERAZINE | 1-[(3, 4-dimethoxyphenyl)methyl]-6, 7-dimethoxy-1, 2, 3, 4-tetrahydroisoquinoline hydrochloride | 1-(3, 4-Dimethoxybenzyl)-6, 7-dimethoxy-1, 2, 3, 4-tetrahydroisoquinolineHydrochloride | HY-N0137 | Norlaudanosine HCl | 1

Specifications & Purity

≥98%

Biochemical and Physiological Mechanisms

Salsolinol hydrochloride derivative. Shows selective dopaminergic neurotoxic effects.

Storage

Store at 2-8°C

Shipped In

Wet ice

This product requires cold chain shipping. Ground and other economy services are not available.

Note

Wherever possible, you should prepare and use solutions on the same day. However, if you need to make up stock solutions in advance, we recommend that you store the solution as aliquots in tightly sealed vials at -20°C. Generally, these will be useable for up to one month. Before use, and prior to opening the vial we recommend that you allow your product to equilibrate to room temperature for at least 1 hour. Need more advice on solubility, usage and handling? Please visit our frequently asked questions (FAQ) page for more details.

Purity

≥98%

Names and Identifiers

• Pubchem Sid: 504768480
• Pubchem Sid Url: https://pubchem.ncbi.nlm.nih.gov/substance/504768480
• Canonical Smiles: COC1=C(C=C(C=C1)CC2C3=CC(=C(C=C3CCN2)OC)OC)OC.Cl
• IUPAC Name: 1-[(3,4-dimethoxyphenyl)methyl]-6,7-dimethoxy-1,2,3,4-tetrahydroisoquinoline;hydrochloride
• InChIKey: VMPLLPIDRGXFTQ-UHFFFAOYSA-N
• INCHI: 1S/C20H25NO4.ClH/c1-22-17-6-5-13(10-18(17)23-2)9-16-15-12-20(25-4)19(24-3)11-14(15)7-8-21-16;/h5-6,10-12,16,21H,7-9H2,1-4H3;1H
• Isomeric SMILES: COC1=C(C=C(C=C1)CC2C3=CC(=C(C=C3CCN2)OC)OC)OC.Cl
• WGK Germany: 3
• RTECS: NX5070700
• Alternate CAS: 6429-04-5
• NSC Number: 118072
• MeSH Entry Terms: tetrahydropapaverine;tetrahydropapaverine hydrochloride
• Molecular Weight: 379.88
• Reaxy-Rn: 3579676
• Reaxys-RN_link_address: https://www.reaxys.com/reaxys/secured/hopinto.do?context=S&query=IDE.XRN=3579676&ln=

Taxonomic Classification

Taxonomy Tree

• Kingdom Organic compounds
  • Superclass Organoheterocyclic compounds
    • Class Isoquinolines and derivatives
      • Subclass Benzylisoquinolines

• Kingdom: Organic compounds
• Superclass: Organoheterocyclic compounds
• Class: Isoquinolines and derivatives
• Subclass: Benzylisoquinolines
• Intermediate Tree Nodes: Not available
• Direct Parent: Benzylisoquinolines
• Alternative Parents: Tetrahydroisoquinolines Dimethoxybenzenes Phenoxy compounds Anisoles Aralkylamines Alkyl aryl ethers Dialkylamines Azacyclic compounds Organopnictogen compounds Organic chloride salts Hydrocarbon derivatives
• Molecular Framework: Aromatic heteropolycyclic compounds
• Substituents: Benzylisoquinoline - Tetrahydroisoquinoline - O-dimethoxybenzene - Dimethoxybenzene - Phenoxy compound - Anisole - Phenol ether - Methoxybenzene - Alkyl aryl ether - Aralkylamine - Monocyclic benzene moiety - Benzenoid - Azacycle - Secondary amine - Ether - Secondary aliphatic amine - Amine - Hydrocarbon derivative - Organooxygen compound - Organonitrogen compound - Organopnictogen compound - Organic nitrogen compound - Organic oxygen compound - Organic salt - Organic chloride salt - Aromatic heteropolycyclic compound
• Description: This compound belongs to the class of organic compounds known as benzylisoquinolines. These are organic compounds containing an isoquinoline to which a benzyl group is attached.
• External Descriptors: Not available

Data sources

1. Djoumbou Feunang Y, Eisner R, Knox C, Chepelev L, Hastings J, Owen G, Fahy E, Steinbeck C, Subramanian S, Bolton E, Greiner R, and Wishart DS. ClassyFire: Automated Chemical Classification With A Comprehensive, Computable Taxonomy. Journal of Cheminformatics, 2016, 8:61.

DOI: 10.1186/s13321-016-0174-y

Chemical and Physical Properties

• Solubility: Soluble in water
• Sensitivity: Moisture sensitive
• Melt Point(°C): 216.0-220.0°C
• Molecular Weight: 379.900 g/mol
• Hydrogen Bond Donor Count: 2
• Hydrogen Bond Acceptor Count: 5
• Rotatable Bond Count: 6
• Exact Mass: 379.155 Da
• Monoisotopic Mass: 379.155 Da
• Topological Polar Surface Area: 49.000 Ų
• Heavy Atom Count: 26
• Formal Charge: 0
• Complexity: 407.000
• Isotope Atom Count: 0
• Defined Atom Stereocenter Count: 0
• Undefined Atom Stereocenter Count: 1
• Defined Bond Stereocenter Count: 0
• Undefined Bond Stereocenter Count: 0
• The total count of all stereochemical bonds: 0
• Covalently-Bonded Unit Count: 2

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