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Pinatuzumab vedotin (anti-CD22) - Primary antibody, specific to CD22, Human IgG1, BINDING AGENT of CD22 binding agent, BINDING AGENT of CD22 binding agent

CAS: 1313706-14-7 Cat. No.: Ab183323
COA
Pinatuzumab vedotin (anti-CD22) - by Aladdin Scientific
AVAILABLE TO ORDER
GRADE & PURITY Animal Free ? Animal-free — produced without animal-derived components to reduce contamination risk. Use in biomanufacturing and culture avoiding animal-origin material. Carrier Free ? Carrier-free — supplied without added carrier protein/stabilizer. Use when carriers (e.g. BSA) would interfere with conjugation or sensitive assays. Recombinant ? Recombinant — produced via recombinant expression for defined sequence and consistency. Use for reproducible, animal-free proteins of known origin. Validated ? Validated grade — performance confirmed in defined applications before release. Use when you want documented assurance the reagent works as stated. ExactAb™ ? ExactAb™ — Aladdin's antibody line emphasizing precision and validated quality. Use for reliable, specificity-validated antibody applications. Low Endotoxin ? Low-endotoxin grade — endotoxin reduced to low controlled levels. Use in sensitive biological work where high endotoxin would interfere. Azide Free ? Azide-free — without sodium azide preservative. Use in conjugations, cell work, or assays where azide is toxic or inhibitory. ≥90%(SDS-PAGE&SEC-HPLC) See COA
Application
Animal Model, ELISA, Flow Cytometry, Functional Assay
Host species
Human
Reactive species
Cynomolgus monkey, Human, Rat
Isotype
Human IgG1
Conjugation
MC-VC-PAB-MMAE
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Size
Status
Price
Qty
100μg
Ab183323-100μg
10
$301.90
1mg
Ab183323-1mg
4
$1,509.90
5mg
Ab183323-5mg
1
$3,775.90
10mg
Ab183323-10mg
1-2 wks(?)
Item is derived from our semi-finished stock and is processed in 1-2 weeks.
$6,059.90
Enter a quantity for the sizes you want to add.
Bulk / Custom
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SDS
Safety data
COA
Certificate
DS
Datasheet
SP
Spec sheet
Overview Specifications Storage and Shipping Images Documentation Advanced Data Associated Targets(Human) Mechanisms of Action Certificates（CoA,COO,BSE/TSE and Analysis Chart) Solution Calculators Reviews
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Why this grade

Carrier Free, Recombinant, ExactAb™, Low Endotoxin, Azide Free, Validated, Animal Free, ≥90%(SDS-PAGE&SEC-HPLC), See COA Animal Free,Azide Free,Carrier Free,ExactAb™,Low Endotoxin,Recombinant,Validated for sensitive chromatographic and analytical workflows requiring minimal baseline interference.

🌡

Storage & shipping

Store at -80°C,Avoid repeated freezing and thawing Ships Dry ice packs + Cold packs Check lot-specific COA for exact specifications.

📋

Quality documents

SDS, COA, datasheet, and spec sheet available for download. Lot-specific COA accessible via lot number lookup.

📚

Literature proof

Cited in 0 peer-reviewed publications across chromatography, organic synthesis, and cross-coupling reactions.

Overview

Pinatuzumab vedotin (anti-CD22), is an antibody-drug conjugate (ADC) composed of CD22 (Sialic acid binding Ig-like lectin 2, SIGLEC2, SIGLEC-2, B-lymphocyte cell adhesion molecule, BL-CAM, Leu-14) antibody and cytotoxic agent monomethyl auristatin E (MMAE) conjugated through maleimidocaproyl-valyl-citrullinyl-p-aminobenzyloxycarbonyl (mc-val-cit-PABC) type linker.
Purity
≥90% (SDS-PAGE&SEC)
Endotoxin Level
< 1.0EU/mg

Specifications

Product Name
Pinatuzumab vedotin (anti-CD22) - Primary antibody, specific to CD22, Human IgG1, BINDING AGENT of CD22 binding agent
Synonyms
B cell receptor CD22 precursor antibody | B lymphocyte cell adhesion molecule antibody | B-cell receptor CD22 antibody | B-lymphocyte cell adhesion molecule antibody | BL CAM antibody | BL-CAM antibody | BLCAM antibody | CD 22 antibody | CD22 antibody | C
Specifications & Purity
Carrier Free, Recombinant, ExactAb™, Low Endotoxin, Azide Free, Validated, Animal Free, ≥90%(SDS-PAGE&SEC-HPLC), See COA
Host species
Human
Specificity
CD22
Conjugation
MC-VC-PAB-MMAE
Grade
Animal Free, Azide Free, Carrier Free, ExactAb™, Low Endotoxin, Recombinant, Validated
Action Type
BINDING AGENT
Mechanism of action
BINDING AGENT of CD22 binding agent
Isotype
Human IgG1
Light Chain Type
kappa
SDS-PAGE
151.97 kDa
Purification Method
Protein A purified
Concentration
See COA
CAS
1313706-14-7
Storage and Shipping
Shape
Liquid
Storage
Store at -80°C,Avoid repeated freezing and thawing
Shipped In
Dry ice packs + Cold packs
Stability And Storage
Store at -80℃ for 24 months. Upon receipt, it is recommended to aliquot. Avoid freeze/thaw cycle.
Images

Pinatuzumab vedotin (anti-CD22) (Ab183323) - Flow Cytometry
Flow Cytometry analysis of human peripheral blood lymphocytes labelling CD22 with Pinatuzumab vedotin (anti-CD22) (Ab183323) conjugated with biotin (right panel) compared with Human IgG (Biotin) (Ab180314) - Isotype Control (left panel) and detected with SA-PE (rp156150). 

Pinatuzumab vedotin (anti-CD22) (Ab183323) - Flow Cytometry
Flow Cytometry analysis of human peripheral blood lymphocytes labelling CD22 (red) with Pinatuzumab vedotin (anti-CD22) (Ab183323) conjugated with biotin and detected with SA-PE (rp156150). Blue - Isotype control, Human IgG (Biotin) (Ab180314). Black - Unlabelled control, cells without incubation with primary antibody.

Pinatuzumab vedotin (anti-CD22) (Ab183323) - Flow Cytometry
Flow Cytometry analysis of Raji cells labelling CD22 (red) with Pinatuzumab vedotin (anti-CD22) (Ab183323). Goat Anti-Human IgG (PE) (Ab175838) at a dilution of 1/1000 was used as the secondary antibody. Blue - Isotype control, human IgG (Ab170213). Black - Unlabelled control, cells without incubation with primary antibody.

Pinatuzumab vedotin (anti-CD22) (Ab183323) - ELISA
Immobilized Recombinant Human Siglec-2/CD22 protein (rp169575) at 1.0 μg/mL can bind Pinatuzumab vedotin (anti-CD22) (Ab183323) with the EC50 of 73.42 ng/mL.

Pinatuzumab vedotin (anti-CD22) (Ab183323) - SEC
The purity of Pinatuzumab vedotin (anti-CD22) (Ab183323) is more than 95% verified by HPLC.

Documentation

📋 Safety Data Sheet (SDS)

Comprehensive hazard, handling, storage, and regulatory compliance document.

Download SDS →

✅ Certificate of Analysis (COA)

Lot-specific quality data. Enter your lot number to retrieve the exact COA.

Look up COA →

📊 Datasheet

Quick-reference summary of product specifications and applications.

View datasheet →

🔬 Specification Sheet

Full quality attributes and acceptance criteria for this grade.

View spec sheet →

Advanced Data

Associated Targets(Human)
CD22 Tclin B-cell receptor CD22 (0 Activities)
Activity TypeActivity Value -log(M)Mechanism of ActionActivity ReferencePublications (PubMed IDs)
Mechanisms of Action
Certificates（CoA,COO,BSE/TSE and Analysis Chart)
C of A & Other Certificates(BSE/TSE, COO):
Analytical Chart:

Find and download the COA for your product by matching the lot number on the packaging.

3 results found

Lot NumberCertificate TypeDateItem
ZJ24F0708977Certificate of AnalysisMay 21, 2026 Ab183323
ZJ24F0708978Certificate of AnalysisMay 21, 2026 Ab183323
ZJ24F0708979Certificate of AnalysisMay 21, 2026 Ab183323
Solution Calculators
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