PROTAC BET Degrader-12 (Compound 8b) is a PROTAC degrader for bromodomain and extra-terminal domain ( BET )-containing proteins, which degrades the BRD3 and BRD4 in a DCAF11-dependent manner. PROTAC BET Degrader-12 inhibits cell viability of KBM7 with a DC 50 of 305.2 nM. (Pink: ligand for target protein (+)-JQ-1 ; Black: linker ; Blue: ligand for E3 ligase )
Specifications
Specifications & Purity
≥98%
Storage
Store at 2-8°C, Protected from light
Shipped In
Wet ice
This product requires cold chain shipping. Ground and other economy services are not available.
Action Type
DEGRADER
Purity
≥98%
Names and Identifiers
Molecular Weight
867.46
Documentation
📋 Safety Data Sheet (SDS)
Comprehensive hazard, handling, storage, and regulatory compliance document.
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Reviews
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