Pyridoxamine-5′-phosphate - ≥95% , CAS No.529-96-4

CAS: 529-96-4 Cat. No.: P330570 Molecular Weight: 248.17 EC Number: 208-471-6 PubChem CID: 1053

GRADE & PURITY ≥95%

Synonyms

{[4-(aminomethyl)-5-hydroxy-6-methylpyridin-3-yl]methoxy}phosphonic acid | BRN 0233653 | NCGC00181045-02 | FT-0632315 | Pyridoxamine 5 inverted exclamation marka-phosphate | 4-Aminomethyl-3-hydroxy-2-methyl-5-((phosphonooxy)methyl)pyridine dihydrate | PYR

Storage

Room temperature,Argon charged

Shipped In

Normal

Overview

Product description

Pyridoxamine is a derivative of vitamin B6. Pyridoxamine is a water-soluble vitamin. Vitamin B6 derivatives contain a core pyridine ring. Pyridoxaminecontains an amino methyl group at pyridine′s 4′ position.

Application

Pyridoxamine-5′-phosphate is suitable:
in the enzymatic synthesis of cytidine diphosphate-4-keto-3, 6-dideoxyglucose；
as a substrate for pyridoxamine-5′-phosphate phosphatase activity assay；
as a substrate to characterize pyridoxine-5′-phosphate oxidase；
for the absorbance and fluorescence studies of properties of NaBH4-reduced glycogen phosphorylase b to probe the microenvironment of PMP residue；
as a substrate for characterization of pyridoxamine-phosphate transaminase(s) from various species and tissues.

Specifications

Synonyms

{[4-(aminomethyl)-5-hydroxy-6-methylpyridin-3-yl]methoxy}phosphonic acid | BRN 0233653 | NCGC00181045-02 | FT-0632315 | Pyridoxamine 5 inverted exclamation marka-phosphate | 4-Aminomethyl-3-hydroxy-2-methyl-5-((phosphonooxy)methyl)pyridine dihydrate | PYR

Specifications & Purity

≥95%

Biochemical and Physiological Mechanisms

Pyridoxal 5′-phosphate can be converted to pyridoxamine-5′-phosphate in the presence of (S)-α-methylbenzylamine (MBA) as the amine donor by using pyruvate transaminase as a biocatalyst.[9] Pyridoxine 5′-phosphate and pyridoxamine 5′-phosphate are oxidized

Storage

Room temperature, Argon charged

Shipped In

Normal

Purity

≥95%

Names and Identifiers

• Pubchem Sid: 504750458
• Pubchem Sid Url: https://pubchem.ncbi.nlm.nih.gov/substance/504750458
• Canonical Smiles: CC1=NC=C(C(=C1O)CN)COP(=O)(O)O
• IUPAC Name: [4-(aminomethyl)-5-hydroxy-6-methylpyridin-3-yl]methyl dihydrogen phosphate
• InChIKey: ZMJGSOSNSPKHNH-UHFFFAOYSA-N
• INCHI: 1S/C8H13N2O5P/c1-5-8(11)7(2-9)6(3-10-5)4-15-16(12,13)14/h3,11H,2,4,9H2,1H3,(H2,12,13,14)
• Isomeric SMILES: CC1=NC=C(C(=C1O)CN)COP(=O)(O)O
• WGK Germany: 2
• RTECS: UT4710000
• PubChem CID: 1053
• Molecular Weight: 248.17

Taxonomic Classification

Taxonomy Tree

• Kingdom Organic compounds
  • Superclass Organoheterocyclic compounds
    • Class Pyridines and derivatives
      • Subclass Pyridoxamines

• Kingdom: Organic compounds
• Superclass: Organoheterocyclic compounds
• Class: Pyridines and derivatives
• Subclass: Pyridoxamines
• Intermediate Tree Nodes: Not available
• Direct Parent: Pyridoxamine 5'-phosphates
• Alternative Parents: Monoalkyl phosphates Methylpyridines Hydroxypyridines Aralkylamines Heteroaromatic compounds Azacyclic compounds Organopnictogen compounds Organooxygen compounds Organic oxides Monoalkylamines Hydrocarbon derivatives
• Molecular Framework: Aromatic heteromonocyclic compounds
• Substituents: Pyridoxamine 5'-phosphate - Monoalkyl phosphate - Aralkylamine - Hydroxypyridine - Methylpyridine - Organic phosphoric acid derivative - Alkyl phosphate - Phosphoric acid ester - Heteroaromatic compound - Azacycle - Primary aliphatic amine - Hydrocarbon derivative - Amine - Primary amine - Organooxygen compound - Organonitrogen compound - Organic nitrogen compound - Organic oxide - Organopnictogen compound - Organic oxygen compound - Aromatic heteromonocyclic compound
• Description: This compound belongs to the class of organic compounds known as pyridoxamine 5'-phosphates. These are heterocyclic aromatic compounds containing a pyridoxamine that carries a phosphate group at the 5'-position.
• External Descriptors: monohydroxypyridine - methylpyridines - aminoalkylpyridine - vitamin B6 phosphate

Data sources

1. Djoumbou Feunang Y, Eisner R, Knox C, Chepelev L, Hastings J, Owen G, Fahy E, Steinbeck C, Subramanian S, Bolton E, Greiner R, and Wishart DS. ClassyFire: Automated Chemical Classification With A Comprehensive, Computable Taxonomy. Journal of Cheminformatics, 2016, 8:61.

DOI: 10.1186/s13321-016-0174-y

Associated Targets(non-human)

Luciferin 4-monooxygenase (66902 Activities)

Explore this target

Activity Type	Relation	Activity value	Units	Action Type	Journal	PubMed Id	doi	Assay Aladdin ID

Mechanisms of Action

Chemical and Physical Properties

• Molecular Weight: 248.170 g/mol
• XLogP3: -4.400
• Hydrogen Bond Donor Count: 4
• Hydrogen Bond Acceptor Count: 7
• Rotatable Bond Count: 4
• Exact Mass: 248.056 Da
• Monoisotopic Mass: 248.056 Da
• Topological Polar Surface Area: 126.000 Ų
• Heavy Atom Count: 16
• Formal Charge: 0
• Complexity: 271.000
• Isotope Atom Count: 0
• Defined Atom Stereocenter Count: 0
• Undefined Atom Stereocenter Count: 0
• Defined Bond Stereocenter Count: 0
• Undefined Bond Stereocenter Count: 0
• The total count of all stereochemical bonds: 0
• Covalently-Bonded Unit Count: 1