GRADE & PURITYAnimal Free?Animal-free — produced without animal-derived components to reduce contamination risk. Use in biomanufacturing and culture avoiding animal-origin material.Carrier Free?Carrier-free — supplied without added carrier protein/stabilizer. Use when carriers (e.g. BSA) would interfere with conjugation or sensitive assays.Bioactive?Bioactive grade — verified to retain biological activity in functional assays. Use when the molecule must be functionally active, not just pure.ActiBioPure™?ActiBioPure™ — Aladdin's premier line for bioactive and recombinant products. Use when both high purity and preserved biological activity are required.His Tag?His tag grade — recombinant protein bearing a His tag for affinity purification/detection. Use to purify, immobilize, or detect the tagged protein.PBS Only?PBS-only formulation — supplied in phosphate-buffered saline with no other additives. Use when you need a clean PBS buffer free of stabilizers/carriers.≥90%(SDS-PAGE)
Accession #
P43489
Protein Tag
C-His
Expression system
HEK293
Endotoxin Concentration
<1.0 EU/μg
Bioactivity
Immobilized Recombinant Human OX40/TNFRSF4 Protein (rp181285) at 1.0 μg/mL can bind BMS-986178 (anti-CD134) (Ab209739) with the EC50 of 38.0 ng/mL. Immobilized Recombinant Human OX40/TNFRSF4 Protein (rp181285) at 1.0 μg/mL can bind Ivuxolimab (anti-CD134) (Ab182815) with the EC50 of 32.7 ng/mL. Immobilized Recombinant Human OX40/TNFRSF4 Protein (rp181285) at 1.0 μg/mL can bind Tavolixizumab (anti-CD134) (Ab182830) with the EC50 of 41.2 ng/mL. Immobilized Recombinant Human OX40/TNFRSF4 Protein (rp181285) at 1.0 μg/mL can bind Cudarolimab (anti-CD134) (Ab182885) with the EC50 of 112.0 ng/mL.
OX40 (CD134) and its binding partner, OX40L (CD252), are members of the tumor necrosis factor receptor/tumor necrosis factor superfamily, is known to break an existing state of tolerance in malignancies, leading to a reactivation of antitumor immunity. Th
Bioactivity
Immobilized Recombinant Human OX40/TNFRSF4 Protein (rp181285) at 1.0 μg/mL can bind BMS-986178 (anti-CD134) (Ab209739) with the EC50 of 38.0 ng/mL. Immobilized Recombinant Human OX40/TNFRSF4 Protein (rp181285) at 1.0 μg/mL can bind Ivuxolimab (anti-CD134) (Ab182815) with the EC50 of 32.7 ng/mL. Immobilized Recombinant Human OX40/TNFRSF4 Protein (rp181285) at 1.0 μg/mL can bind Tavolixizumab (anti-CD134) (Ab182830) with the EC50 of 41.2 ng/mL. Immobilized Recombinant Human OX40/TNFRSF4 Protein (rp181285) at 1.0 μg/mL can bind Cudarolimab (anti-CD134) (Ab182885) with the EC50 of 112.0 ng/mL.
31.6- 49.3 kDa, under reducing conditions; 28.9-49.9 kDa, under non-reducing conditions
Molecule Type
Protein
Storage and Shipping
Reconstitution
We recommend that this vial be briefly centrifuged prior to opening to bring the contents to the bottom. Reconstitute at 0.5 mg/mL in sterile distilled water. Stock solutions should be apportioned into working aliquots and stored at ≤ -20 °C. Further dilutions should be made in appropriate buffered solutions.
Storage
Store at -20°C,Avoid repeated freezing and thawing
Shipped In
Ice chest + Ice pads
Stability And Storage
Store at -20°C for 1 year. Avoid freeze/thaw cycle.
Images
Recombinant Human OX40/TNFRSF4 Protein (rp181285) - ELISA Immobilized Recombinant Human OX40/TNFRSF4 Protein (rp181285) at 1.0 μg/mL can bind BMS-986178 (anti-CD134) (Ab209739) with the EC₅₀ of 38.0 ng/mL.
Recombinant Human OX40/TNFRSF4 Protein (rp181285) - ELISA Immobilized Recombinant Human OX40/TNFRSF4 Protein (rp181285) at 1.0 μg/mL can bind Ivuxolimab (anti-CD134) (Ab182815) with the EC₅₀ of 32.7 ng/mL.
Recombinant Human OX40/TNFRSF4 Protein (rp181285) - ELISA Immobilized Recombinant Human OX40/TNFRSF4 Protein (rp181285) at 1.0 μg/mL can bind Tavolixizumab (anti-CD134) (Ab182830) with the EC₅₀ of 41.2 ng/mL.
Recombinant Human OX40/TNFRSF4 Protein (rp181285) - ELISA Immobilized Recombinant Human OX40/TNFRSF4 Protein (rp181285) at 1.0 μg/mL can bind Cudarolimab (anti-CD134) (Ab182885) with the EC₅₀ of 112.0 ng/mL.
Recombinant Human OX40/TNFRSF4 Protein (rp181285) - SDS-PAGE 3 μg/lane of Recombinant Human OX40/TNFRSF4 Protein was resolved with SDS-PAGE under reducing (R) and non-reducing (N) conditions and visualized by Coomassie® Blue staining, showing a band at 31.6- 49.3 kDa under reducing conditions and 28.9-49.9 kDa under non-reducing conditions.
Documentation
📋 Safety Data Sheet (SDS)
Comprehensive hazard, handling, storage, and regulatory compliance document.
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