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RFRP 3 (human) TFA, CAS No.311309-27-0(free)
AVAILABLE TO ORDER
GRADE & PURITY ≥98%
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Why this grade
≥98% for sensitive chromatographic and analytical workflows requiring minimal baseline interference.
Storage & shipping
Store at -20°C Ships Ice chest + Ice pads Check lot-specific COA for exact specifications.
Quality documents
SDS, COA, datasheet, and spec sheet available for download. Lot-specific COA accessible via lot number lookup.
Literature proof
Cited in 0 peer-reviewed publications across chromatography, organic synthesis, and cross-coupling reactions.
Overview
Product Description
RFRP-3 TFA efficiently inhibits forskolin-induced production of cAMP with an IC50 of 0.7 nM.
Scatchard-plot analysis shows that 125I-labelled hRFRP-3 has a single class of high-affinity binding sites for the membrane fractions of CHO cells expressing rat OT7T022, the Kd value and the Bmax values are 0.19 nM and 1.3 pM, respectively.
RFRP-3 TFA specifically stimulate cells transfected with a new orphan 7TMR, OT7T022, it binds to OT7T022 as a specific ligand with high affinity (Kd= 0.19 nM).
RFRP-3 (10-8 to 10-14M) has no effect on LH and FSH levels alone, but when it combines with GnRH, LH and FSH secretion is significantly reduced by the combination.
Specifications
Product Name
RFRP 3 (human) TFA, CAS No.311309-27-0(free)
Synonyms
Neuropeptide VF(124-131)(human) TFA | RFRP-3 human trifluoroacetate salt | Neuropeptide VF (124-131), NPVF, RFamide-related peptide-3
Specifications & Purity
≥98%
Biochemical and Physiological Mechanisms
RFRP-3 (RFamide-related peptide-3) is a homolog of avian gonadotropin-inhibitory hormone. RFRP-3 binds to the GPR147 receptor (also known as neuropeptide FF receptor 1). RFRP-3 blocks release of gonadotropin from the pituitary, and inhibits FSH-, LH- and
Sequence
Val-Pro-Asn-Leu-Pro-Gln-Arg-Phe-NH2
CAS
311309-27-0(free)
Molecule Type
Peptide
Storage and Shipping
Storage
Store at -20°C
Shipped In
Ice chest + Ice pads
Documentation
📋 Safety Data Sheet (SDS)
Comprehensive hazard, handling, storage, and regulatory compliance document.
Download SDS →✅ Certificate of Analysis (COA)
Lot-specific quality data. Enter your lot number to retrieve the exact COA.
Look up COA →🔬 Specification Sheet
Full quality attributes and acceptance criteria for this grade.
View spec sheet →Advanced Data
Certificates（CoA,COO,BSE/TSE and Analysis Chart)
C of A & Other Certificates(BSE/TSE, COO):
Analytical Chart:
Find and download the COA for your product by matching the lot number on the packaging.
| Lot Number | Certificate Type | Date | Item |
|---|---|---|---|
 G2209320 | Certificate of Analysis | Apr 03, 2025 | R409332 |
| G2209322 | Certificate of Analysis | Apr 03, 2025 | R409332 |
| G2209325 | Certificate of Analysis | Apr 03, 2025 | R409332 |
| G2209327 | Certificate of Analysis | Apr 03, 2025 | R409332 |
| G2209332 | Certificate of Analysis | Apr 03, 2025 | R409332 |
| G2209333 | Certificate of Analysis | Apr 03, 2025 | R409332 |
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