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(RS)-(Tetrazol-5-yl)glycine - Moligand™, ≥98%(HPLC) , Agonist of GluN1;Agonist of GluN2A;Agonist of GluN2B;Agonist of GluN2C;Agonist of GluN2D, CAS No.138199-51-6, Agonist of GluN1;Agonist of GluN2A;Agonist of GluN2B;Agonist of GluN2C;Agonist of GluN2D

CAS: 138199-51-6 Cat. No.: R287510 Molecular Weight: 143.1 PubChem CID: 126383
COA
(RS)-(Tetrazol-5-yl)glycine - Moligand™, ≥98%(HPLC) CAS No(138199-51-6) by Aladdin Scientific
AVAILABLE TO ORDER
GRADE & PURITY Moligand™ ? Moligand™ — Aladdin's line of ligands and bioactive small molecules. Use for receptor, pathway, and binding studies needing defined small-molecule tools. ≥98%(HPLC)
Synonyms
Tetrazol-5-yl-gly | 2-amino-2-(1H-1,2,3,4-tetrazol-5-yl)acetic acid | 2H-Tetrazole-5-acetic acid, alpha-amino- | Z1198152530 | (RS)-(tetrazol-5-yl)glycine | NCGC00024531-02 | 2-amino-2-(1H-tetrazol-5-yl)acetic acid | LY 285 265 | 1H-TETRAZOLE-5-ACETIC ACI
Storage
Room temperature
Shipped In
Normal
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 ·  off list, applied to all prices below.
Size
Status
Price
Qty
10mg
R287510-10mg
8-12 wks(?) Production requires sourcing of materials. We appreciate your patience and understanding.
$455.90
50mg
R287510-50mg
8-12 wks(?) Production requires sourcing of materials. We appreciate your patience and understanding.
$1,874.90
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SDS
Safety data
COA
Certificate
DS
Datasheet
SP
Spec sheet
Specifications Names and Identifiers Documentation Advanced Data Taxonomic Classification 3D Structure Associated Targets(Human) Associated Targets(non-human) Mechanisms of Action Certificates（CoA,COO,BSE/TSE and Analysis Chart) Chemical and Physical Properties Solution Calculators Reviews
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Why this grade

Moligand™, ≥98%(HPLC) Moligand™ for sensitive chromatographic and analytical workflows requiring minimal baseline interference.

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Storage & shipping

Room temperature Ships Normal Check lot-specific COA for exact specifications.

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Quality documents

SDS, COA, datasheet, and spec sheet available for download. Lot-specific COA accessible via lot number lookup.

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Literature proof

Cited in 0 peer-reviewed publications across chromatography, organic synthesis, and cross-coupling reactions.

Specifications

Synonyms
Tetrazol-5-yl-gly | 2-amino-2-(1H-1, 2, 3, 4-tetrazol-5-yl)acetic acid | 2H-Tetrazole-5-acetic acid, alpha-amino- | Z1198152530 | (RS)-(tetrazol-5-yl)glycine | NCGC00024531-02 | 2-amino-2-(1H-tetrazol-5-yl)acetic acid | LY 285 265 | 1H-TETRAZOLE-5-ACETIC ACI
Specifications & Purity
Moligand™, ≥98%(HPLC)
Biochemical and Physiological Mechanisms
Potent NMDA receptor agonist, approximately 20 times more active than NMDA.
Storage
Room temperature
Shipped In
Normal
Grade
Moligand™
Action Type
AGONIST
Mechanism of action
Agonist of GluN1;Agonist of GluN2A;Agonist of GluN2B;Agonist of GluN2C;Agonist of GluN2D
Purity
≥98%(HPLC)
Names and Identifiers
Canonical SmilesC1(=NNN=N1)C(C(=O)O)N
IUPAC Name2-amino-2-(2H-tetrazol-5-yl)acetic acid
InChIKeyUKBRUIZWQZHXFL-UHFFFAOYSA-N
INCHI1S/C3H5N5O2/c4-1(3(9)10)2-5-7-8-6-2/h1H,4H2,(H,9,10)(H,5,6,7,8)
Isomeric SMILES C1(=NNN=N1)C(C(=O)O)N
Alternate CAS 138199-51-6
PubChem CID 126383
MeSH Entry Terms (tetrazol-5-yl)glycine;LY 285 265;LY-285,265;tetrazol-5-yl-Gly
Molecular Weight 143.1

Documentation

📋 Safety Data Sheet (SDS)

Comprehensive hazard, handling, storage, and regulatory compliance document.

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✅ Certificate of Analysis (COA)

Lot-specific quality data. Enter your lot number to retrieve the exact COA.

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📊 Datasheet

Quick-reference summary of product specifications and applications.

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🔬 Specification Sheet

Full quality attributes and acceptance criteria for this grade.

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Advanced Data

Taxonomic Classification

Taxonomy Tree

KingdomOrganic compounds
SuperclassOrganic acids and derivatives
ClassCarboxylic acids and derivatives
SubclassAmino acids, peptides, and analogues
Intermediate Tree Nodes Amino acids and derivatives - Alpha amino acids and derivatives
Direct ParentAlpha amino acids
Alternative Parents Aralkylamines  Tetrazoles  Heteroaromatic compounds  Amino acids  Monocarboxylic acids and derivatives  Carboxylic acids  Azacyclic compounds  Organopnictogen compounds  Organic oxides  Monoalkylamines  Hydrocarbon derivatives  Carbonyl compounds  
Molecular FrameworkAromatic heteromonocyclic compounds
Substituents Alpha-amino acid - Aralkylamine - Azole - Tetrazole - Heteroaromatic compound - Amino acid - Carboxylic acid - Monocarboxylic acid or derivatives - Organoheterocyclic compound - Azacycle - Organopnictogen compound - Primary amine - Organooxygen compound - Organonitrogen compound - Amine - Primary aliphatic amine - Organic nitrogen compound - Carbonyl group - Organic oxide - Organic oxygen compound - Hydrocarbon derivative - Aromatic heteromonocyclic compound
DescriptionThis compound belongs to the class of organic compounds known as alpha amino acids. These are amino acids in which the amino group is attached to the carbon atom immediately adjacent to the carboxylate group (alpha carbon).
External Descriptors non-proteinogenic alpha-amino acid
3D Structure
Interactive Chemical Structure Model





Associated Targets(Human)
GRIN1 Tclin Glutamate receptor ionotropic, NMDA 1 (0 Activities)
Activity TypeActivity Value -log(M)Mechanism of ActionActivity ReferencePublications (PubMed IDs)
GRIN2A Tclin Glutamate receptor ionotropic, NMDA 2A (0 Activities)
Activity TypeActivity Value -log(M)Mechanism of ActionActivity ReferencePublications (PubMed IDs)
GRIN2B Tclin Glutamate receptor ionotropic, NMDA 2B (0 Activities)
Activity TypeActivity Value -log(M)Mechanism of ActionActivity ReferencePublications (PubMed IDs)
GRIN2C Tclin Glutamate receptor ionotropic, NMDA 2C (0 Activities)
Activity TypeActivity Value -log(M)Mechanism of ActionActivity ReferencePublications (PubMed IDs)
GRIN2D Tclin Glutamate receptor ionotropic, NMDA 2D (0 Activities)
Activity TypeActivity Value -log(M)Mechanism of ActionActivity ReferencePublications (PubMed IDs)
HepG2 (196354 Activities)
Activity TypeRelationActivity valueUnitsAction TypeJournalPubMed IddoiAssay Aladdin ID
KDM4A Tchem Lysine-specific demethylase 4A (52245 Activities)
Activity TypeRelationActivity valueUnitsAction TypeJournalPubMed IddoiAssay Aladdin ID
Associated Targets(non-human)
Hdac6 Histone deacetylase 6 (222 Activities)
Activity TypeRelationActivity valueUnitsAction TypeJournalPubMed IddoiAssay Aladdin ID
rep Replicase polyprotein 1ab (378 Activities)
Activity TypeRelationActivity valueUnitsAction TypeJournalPubMed IddoiAssay Aladdin ID
FTL Ferritin light chain (43324 Activities)
Activity TypeRelationActivity valueUnitsAction TypeJournalPubMed IddoiAssay Aladdin ID
Grin1 Glutamate NMDA receptor (6467 Activities)
Activity TypeRelationActivity valueUnitsAction TypeJournalPubMed IddoiAssay Aladdin ID
Slc1a5 Amino acid transporter (271 Activities)
Activity TypeRelationActivity valueUnitsAction TypeJournalPubMed IddoiAssay Aladdin ID
Mechanisms of Action
Certificates（CoA,COO,BSE/TSE and Analysis Chart)
C of A & Other Certificates(BSE/TSE, COO):
Analytical Chart:
Chemical and Physical Properties
SolubilitySolvent:water, Max Conc. mg/mL: None, Max Conc. mM: 50
Molecular Weight143.100 g/mol
XLogP3-4.100
Hydrogen Bond Donor Count3
Hydrogen Bond Acceptor Count6
Rotatable Bond Count2
Exact Mass143.044 Da
Monoisotopic Mass143.044 Da
Topological Polar Surface Area118.000 Ų
Heavy Atom Count10
Formal Charge0
Complexity139.000
Isotope Atom Count0
Defined Atom Stereocenter Count0
Undefined Atom Stereocenter Count1
Defined Bond Stereocenter Count0
Undefined Bond Stereocenter Count0
The total count of all stereochemical bonds0
Covalently-Bonded Unit Count1
Solution Calculators
Reviews

Customer Reviews

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View related series

GluN1 Agonist (8) GluN2A Agonist (8) GluN2B Agonist (8) GluN2C Agonist (7) GluN2D Agonist (7) Ion channel (4039)
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