Saxagliptin hydrochloride - ≥97% , Dipeptidyl peptidase IV inhibitor, CAS No.709031-78-7, Dipeptidyl peptidase IV inhibitor

CAS: 709031-78-7 Cat. No.: S177249 Molecular Weight: 351.871 EC Number: 696-124-3 PubChem CID: 49800073
AVAILABLE TO ORDER
GRADE & PURITY ≥97%
Synonyms
(1S,3S,5S)-2-[(2S)-Amino(3-hydroxytricyclo[3.3.1.13,7]dec-1-yl)acetyl]-2-azabicyclo[3.1.0]hexane-3-carbonitrile hydrochloride | C18H26ClN3O2 | Z8J84YIX6L | Saxagliptin HCl | EN300-26976214 | TUAZNHHHYVBVBR-NHKADLRUSA-N | Saxagliptin hydrochloride | 536BQ2
Storage
Store at 2-8°C
Shipped In
Wet ice
 ·  off list, applied to all prices below.
Size
Status
Price
Qty
250mg
S177249-250mg
3

$46.90

$70.90
Save $24.00 (33.85%)
1g
S177249-1g
3

$150.90

$226.90
Save $76.00 (33.49%)
5g
S177249-5g
1

$562.90

$844.90
Save $282.00 (33.38%)
Enter a quantity for the sizes you want to add.
🧪

Why this grade

≥97% for sensitive chromatographic and analytical workflows requiring minimal baseline interference.

🌡

Storage & shipping

Store at 2-8°C Ships Wet ice Check lot-specific COA for exact specifications.

📋

Quality documents

SDS, COA, datasheet, and spec sheet available for download. Lot-specific COA accessible via lot number lookup.

📚

Literature proof

Cited in 0 peer-reviewed publications across chromatography, organic synthesis, and cross-coupling reactions.

Specifications

Synonyms
(1S, 3S, 5S)-2-[(2S)-Amino(3-hydroxytricyclo[3.3.1.13, 7]dec-1-yl)acetyl]-2-azabicyclo[3.1.0]hexane-3-carbonitrile hydrochloride | C18H26ClN3O2 | Z8J84YIX6L | Saxagliptin HCl | EN300-26976214 | TUAZNHHHYVBVBR-NHKADLRUSA-N | Saxagliptin hydrochloride | 536BQ2
Specifications & Purity
≥97%
Biochemical and Physiological Mechanisms
High affinity DPP-IV inhibitor (Ki= 0.6 nM). Inhibits plasma DPP-IV (87%). Elicits enhanced glucose clearance in Zuckerfa/farats.
Storage
Store at 2-8°C
Shipped In
Wet ice
This product requires cold chain shipping. Ground and other economy services are not available.
Action Type
INHIBITOR
Mechanism of action
Dipeptidyl peptidase IV inhibitor
Purity
≥97%
Names and Identifiers
Pubchem Sid504770933
Pubchem Sid Urlhttps://pubchem.ncbi.nlm.nih.gov/substance/504770933
Canonical SmilesC1C2CC2N(C1C#N)C(=O)C(C34CC5CC(C3)CC(C5)(C4)O)N.Cl
IUPAC Name(1S,3S,5S)-2-[(2S)-2-amino-2-(3-hydroxy-1-adamantyl)acetyl]-2-azabicyclo[3.1.0]hexane-3-carbonitrile;hydrochloride
InChIKeyTUAZNHHHYVBVBR-NHKADLRUSA-N
INCHI1S/C18H25N3O2.ClH/c19-8-13-2-12-3-14(12)21(13)16(22)15(20)17-4-10-1-11(5-17)7-18(23,6-10)9-17;/h10-15,23H,1-7,9,20H2;1H/t10?,11?,12-,13+,14+,15-,17?,18?;/m1./s1
Isomeric SMILES C1[C@@H]2C[C@@H]2N([C@@H]1C#N)C(=O)[C@H](C34CC5CC(C3)CC(C5)(C4)O)N.Cl
PubChem CID 49800073
Molecular Weight 351.871

Documentation

📋 Safety Data Sheet (SDS)

Comprehensive hazard, handling, storage, and regulatory compliance document.

Download SDS →

✅ Certificate of Analysis (COA)

Lot-specific quality data. Enter your lot number to retrieve the exact COA.

Look up COA →

📊 Datasheet

Quick-reference summary of product specifications and applications.

View datasheet →

🔬 Specification Sheet

Full quality attributes and acceptance criteria for this grade.

View spec sheet →

Advanced Data

Taxonomic Classification

Taxonomy Tree

KingdomOrganic compounds
SuperclassOrganic acids and derivatives
ClassCarboxylic acids and derivatives
SubclassAmino acids, peptides, and analogues
Intermediate Tree Nodes Amino acids and derivatives - Alpha amino acids and derivatives
Direct ParentAlpha amino acid amides
Alternative Parents N-acylpiperidines  N-acylpyrrolidines  Tertiary carboxylic acid amides  Tertiary alcohols  Cyclic alcohols and derivatives  Nitriles  Azacyclic compounds  Organopnictogen compounds  Organic oxides  Monoalkylamines  Hydrochlorides  Hydrocarbon derivatives  Carbonyl compounds  
Molecular FrameworkAliphatic heteropolycyclic compounds
Substituents Alpha-amino acid amide - N-acyl-piperidine - N-acylpyrrolidine - Piperidine - Cyclic alcohol - Pyrrolidine - Tertiary alcohol - Tertiary carboxylic acid amide - Carboxamide group - Carbonitrile - Nitrile - Azacycle - Organoheterocyclic compound - Organooxygen compound - Organonitrogen compound - Alcohol - Hydrocarbon derivative - Organic oxide - Primary aliphatic amine - Organopnictogen compound - Organic oxygen compound - Carbonyl group - Organic nitrogen compound - Primary amine - Hydrochloride - Amine - Aliphatic heteropolycyclic compound
DescriptionThis compound belongs to the class of organic compounds known as alpha amino acid amides. These are amide derivatives of alpha amino acids.
External Descriptors Not available
3D Structure
Interactive Chemical Structure Model





Associated Targets(Human)
ABCC2 Tchem Canalicular multispecific organic anion transporter 1 (1191 Activities)
Activity TypeRelationActivity valueUnitsAction TypeJournalPubMed IddoiAssay Aladdin ID
ABCB11 Tchem Bile salt export pump (2311 Activities)
Activity TypeRelationActivity valueUnitsAction TypeJournalPubMed IddoiAssay Aladdin ID
ABCC3 Tbio Canalicular multispecific organic anion transporter 2 (718 Activities)
Activity TypeRelationActivity valueUnitsAction TypeJournalPubMed IddoiAssay Aladdin ID
Mechanisms of Action
Certificates(CoA,COO,BSE/TSE and Analysis Chart)
C of A & Other Certificates(BSE/TSE, COO):
Analytical Chart:

Find and download the COA for your product by matching the lot number on the packaging.

4 results found

Lot NumberCertificate TypeDateItem
J22181122Certificate of AnalysisAug 07, 2025 S177249
J22181145Certificate of AnalysisAug 07, 2025 S177249
J22181151Certificate of AnalysisAug 07, 2025 S177249
K2415085Certificate of AnalysisJul 28, 2022 S177249
Chemical and Physical Properties
SolubilitySolvent:water, Max Conc. mg/mL: 35.19, Max Conc. mM: 100; Solvent:DMSO, Max Conc. mg/mL: 35.19, Max Conc. mM: 100
Molecular Weight351.900 g/mol
XLogP3
Hydrogen Bond Donor Count3
Hydrogen Bond Acceptor Count4
Rotatable Bond Count2
Exact Mass351.171 Da
Monoisotopic Mass351.171 Da
Topological Polar Surface Area90.400 Ų
Heavy Atom Count24
Formal Charge0
Complexity609.000
Isotope Atom Count0
Defined Atom Stereocenter Count4
Undefined Atom Stereocenter Count2
Defined Bond Stereocenter Count0
Undefined Bond Stereocenter Count0
The total count of all stereochemical bonds0
Covalently-Bonded Unit Count2
Solution Calculators
Reviews

Customer Reviews

Shall we send you a message when we have discounts available?

Remind me later

Thank you! Please check your email inbox to confirm.

Oops! Notifications are disabled.