Succinyl coenzyme A sodium salt - ≥85% , CAS No.108347-97-3

CAS: 108347-97-3 Cat. No.: S343093 Molecular Weight: 867.61 (non sodium salt) EC Number: 634-622-4

GRADE & PURITY ≥85%

Synonyms

4-[2-[3-[[4-[[[(2R,3S,4R,5R)-5-(6-aminopurin-9-yl)-4-hydroxy-3-[hydroxy(oxido)phosphoryl]oxyoxolan-2-yl]methoxy-hydroxyphosphoryl]oxy-hydroxyphosphoryl]oxy-2-hydroxy-3,3-dimethylbutanoyl]amino]propanoylamino]ethylsulfanyl]-4-oxobutanoate | Succinyl coenzy

Storage

Store at -20°C

Shipped In

Ice chest + Ice pads

Overview

Succinyl coenzyme A sodium salt is an intermediate in the cycle of citric acid. In this cycle, Succinyl coenzyme A sodium salt is converted to succinate, a metabolic intermediate for various biological purposes. Succinyl coenzyme A sodium salt along with glycine are capable of forming δ-aminolevulinic acid, a vital first step in porphyrin and heme synthesis. A vitamin B|12|deficiency can lead to a Succinyl coenzyme A sodium salt deficiency, thereby disrupting heme and energy production. In other words, a Succinyl coenzyme A sodium salt deficiency is tantamount to neuromotor dysfunction.

Specifications

Synonyms

4-[2-[3-[[4-[[[(2R, 3S, 4R, 5R)-5-(6-aminopurin-9-yl)-4-hydroxy-3-[hydroxy(oxido)phosphoryl]oxyoxolan-2-yl]methoxy-hydroxyphosphoryl]oxy-hydroxyphosphoryl]oxy-2-hydroxy-3, 3-dimethylbutanoyl]amino]propanoylamino]ethylsulfanyl]-4-oxobutanoate | Succinyl coenzy

Specifications & Purity

≥85%

Biochemical and Physiological Mechanisms

Succinyl-CoA is an intermediate in the citric acid cycle. It catalyzes the decarboxylation of α-ketoglutarate by α-ketoglutarate dehydrogenase. Succinyl-CoA can also be formed from propionyl-CoA during beta-oxidation of single-chain fatty acids. Succinyl-

Storage

Store at -20°C

Shipped In

Ice chest + Ice pads

This product requires cold chain shipping. Ground and other economy services are not available.

Purity

≥85%

Names and Identifiers

• Canonical Smiles: CC(C)(COP(=O)(O)OP(=O)(O)OCC1C(C(C(O1)N2C=NC3=C(N=CN=C32)N)O)OP(=O)(O)[O-])C(C(=O)NCCC(=O)NCCSC(=O)CCC(=O)[O-])O
• IUPAC Name: 4-[2-[3-[[4-[[[(2R,3S,4R,5R)-5-(6-aminopurin-9-yl)-4-hydroxy-3-[hydroxy(oxido)phosphoryl]oxyoxolan-2-yl]methoxy-hydroxyphosphoryl]oxy-hydroxyphosphoryl]oxy-2-hydroxy-3,3-dimethylbutanoyl]amino]propanoylamino]ethylsulfanyl]-4-oxobutanoate
• InChIKey: VNOYUJKHFWYWIR-FZEDXVDRSA-L
• INCHI: 1S/C25H40N7O19P3S/c1-25(2,20(38)23(39)28-6-5-14(33)27-7-8-55-16(36)4-3-15(34)35)10-48-54(45,46)51-53(43,44)47-9-13-19(50-52(40,41)42)18(37)24(49-13)32-12-31-17-21(26)29-11-30-22(17)32/h11-13,18-20,24,37-38H,3-10H2,1-2H3,(H,27,33)(H,28,39)(H,34,35)(H,43,44)(H,45,46)(H2,26,29,30)(H2,40,41,42)/p-2/t13-,18-,19-,20?,24-/m1/s1
• Isomeric SMILES: CC(C)(COP(=O)(O)OP(=O)(O)OC[C@@H]1[C@H]([C@H]([C@@H](O1)N2C=NC3=C(N=CN=C32)N)O)OP(=O)(O)[O-])C(C(=O)NCCC(=O)NCCSC(=O)CCC(=O)[O-])O
• WGK Germany: 3
• Molecular Weight: 867.61 (non sodium salt)
• Reaxy-Rn: 604152
• Reaxys-RN_link_address: https://www.reaxys.com/reaxys/secured/hopinto.do?context=S&query=IDE.XRN=604152&ln=

Chemical and Physical Properties

• Solubility: Soluble in 0.1ml water (5 mg).water: 50 mg/mL, clear, colorless；PBS (pH 7.2): 10 mg/ml

References

1. Yao Chen, Luhuizi Shan, Wenxi Zheng, Jie Chen, Linfang Deng, Xu Tian, Ruili Xie, Yunhong Yang, Lin Zhang, Bingxian Yang.  (2024)  Global lysine succinylation analysis unveils post-translational regulation effect on phenylpropanoid metabolism remodeling during Lonicera japonica flower development.  PLANT PHYSIOLOGY AND BIOCHEMISTRY,      [PMID:39084169] [10.1016/j.plaphy.2024.108978]