Triprolidine hydrochloride monohydrate - ≥99% , Histamine H1 receptor antagonist, CAS No.6138-79-0, Histamine H1 receptor antagonist

CAS: 6138-79-0 Cat. No.: T333593 Molecular Weight: 332.9 EC Number: 627-740-2 PubChem CID: 5284472

GRADE & PURITY ≥99%

Synonyms

TRILITRON COMPONENT TRIPROLIDINE HYDROCHLORIDE | Triprolidine hydrochloride [USP:JAN] | TRIPROLIDINE HYDROCHLORIDE [VANDF] | CORPHED COMPONENT TRIPROLIDINE HYDROCHLORIDE | NSC 757361 | s5447 | Actidilon | TRIPROLIDINE HYDROCHLORIDE MONOHYDRATE [MART.] | A

Storage

Store at 2-8°C

Shipped In

Wet ice

Overview

trans|-Triprolidine hydrochloride is a potent Histamine H1 receptor antagonist.

Specifications

Synonyms

TRILITRON COMPONENT TRIPROLIDINE HYDROCHLORIDE | Triprolidine hydrochloride [USP:JAN] | TRIPROLIDINE HYDROCHLORIDE [VANDF] | CORPHED COMPONENT TRIPROLIDINE HYDROCHLORIDE | NSC 757361 | s5447 | Actidilon | TRIPROLIDINE HYDROCHLORIDE MONOHYDRATE [MART.] | A

Specifications & Purity

≥99%

Storage

Store at 2-8°C

Shipped In

Wet ice

This product requires cold chain shipping. Ground and other economy services are not available.

Action Type

ANTAGONIST

Mechanism of action

Histamine H1 receptor antagonist

Purity

≥99%

Names and Identifiers

• Pubchem Sid: 504763491
• Pubchem Sid Url: https://pubchem.ncbi.nlm.nih.gov/substance/504763491
• Canonical Smiles: CC1=CC=C(C=C1)C(=CCN2CCCC2)C3=CC=CC=N3.O.Cl
• IUPAC Name: 2-[(E)-1-(4-methylphenyl)-3-pyrrolidin-1-ylprop-1-enyl]pyridine;hydrate;hydrochloride
• InChIKey: CUZMOIXUFHOLLN-UMVVUDSKSA-N
• INCHI: 1S/C19H22N2.ClH.H2O/c1-16-7-9-17(10-8-16)18(19-6-2-3-12-20-19)11-15-21-13-4-5-14-21;;/h2-3,6-12H,4-5,13-15H2,1H3;1H;1H2/b18-11+
• Isomeric SMILES: CC1=CC=C(C=C1)/C(=C\CN2CCCC2)/C3=CC=CC=N3.O.Cl
• WGK Germany: 3
• RTECS: UT7658000
• PubChem CID: 5284472
• Molecular Weight: 332.9

Taxonomic Classification

Taxonomy Tree

• Kingdom Organic compounds
  • Superclass Benzenoids
    • Class Benzene and substituted derivatives
      • Subclass Styrenes

• Kingdom: Organic compounds
• Superclass: Benzenoids
• Class: Benzene and substituted derivatives
• Subclass: Styrenes
• Intermediate Tree Nodes: Not available
• Direct Parent: Styrenes
• Alternative Parents: Toluenes Pyridines and derivatives N-alkylpyrrolidines Heteroaromatic compounds Trialkylamines Azacyclic compounds Organopnictogen compounds Organic oxides Organic chloride salts Hydrocarbon derivatives
• Molecular Framework: Aromatic heteromonocyclic compounds
• Substituents: Styrene - Toluene - Pyridine - N-alkylpyrrolidine - Pyrrolidine - Heteroaromatic compound - Tertiary amine - Tertiary aliphatic amine - Azacycle - Organoheterocyclic compound - Amine - Organic salt - Organic chloride salt - Hydrocarbon derivative - Organic oxide - Organopnictogen compound - Organic oxygen compound - Organic nitrogen compound - Organonitrogen compound - Aromatic heteromonocyclic compound
• Description: This compound belongs to the class of organic compounds known as styrenes. These are organic compounds containing an ethenylbenzene moiety.
• External Descriptors: hydrate

Data sources

1. Djoumbou Feunang Y, Eisner R, Knox C, Chepelev L, Hastings J, Owen G, Fahy E, Steinbeck C, Subramanian S, Bolton E, Greiner R, and Wishart DS. ClassyFire: Automated Chemical Classification With A Comprehensive, Computable Taxonomy. Journal of Cheminformatics, 2016, 8:61.

DOI: 10.1186/s13321-016-0174-y

Chemical and Physical Properties

• Solubility: Soluble in water (100 mg/ml), alcohol (1:1.5), and chloroform (1:<1).DMSO:186.3 mM
• Sensitivity: Moisture sensitive
• Refractive Index: n20D~1.59 (Predicted)
• Boil Point(°C): 462° C (dec.) at 760 mmHg
• Melt Point(°C): 115-116° C
• Molecular Weight: 332.900 g/mol
• Hydrogen Bond Donor Count: 2
• Hydrogen Bond Acceptor Count: 3
• Rotatable Bond Count: 4
• Exact Mass: 332.166 Da
• Monoisotopic Mass: 332.166 Da
• Topological Polar Surface Area: 17.100 Ų
• Heavy Atom Count: 23
• Formal Charge: 0
• Complexity: 335.000
• Isotope Atom Count: 0
• Defined Atom Stereocenter Count: 0
• Undefined Atom Stereocenter Count: 0
• Defined Bond Stereocenter Count: 1
• Undefined Bond Stereocenter Count: 0
• The total count of all stereochemical bonds: 1
• Covalently-Bonded Unit Count: 3

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