1，11-Diazido-3，6，9-trioxaundecane - ≥95% , CAS No.101187-39-7

CAS: 101187-39-7 Cat. No.: D132588 Molecular Weight: 244.25 EC Number: 802-438-5

GRADE & PURITY ≥95%

Synonyms

Azido-PEG3-azido | Bis-PEG3-Azide | Ethane, 1,1'-oxybis[2-(2-azidoethoxy)- | Azide-PEG4-Azide | 1-AZIDO-2-(2-(2-(2-AZIDOETHOXY)ETHOXY)ETHOXY)ETHANE | A927266 | AKOS025293963 | D84626 | AS-63586 | LCZC1248 | SCHEMBL13434049 | 1-AZIDO-2-{2-[2-(2-AZIDOETHOXY

Storage

Store at -20°C,Argon charged

Shipped In

Ice chest + Ice pads

Overview

It is an oligoether compound derived from poly(ethylene glycol) useful in the preparation of hydrophilic spacers for tethering and cross-linking molecules. This diazide was converted into the unsymmetrically substituted 1-amino-11-azido-3,6,9-trioxaundecane which is described to be a very useful hydrophilic linker compound.
Homobifunctional PEG azide click chemistry linker. Azide functional groups will react via a copper catalyzed or strain promoted 1,3-dipolar cycloaddition click reaction with terminal alkynes and cyclooctyne derivatives to yield a stable triazole linkage.

Specifications

Synonyms

Azido-PEG3-azido | Bis-PEG3-Azide | Ethane, 1, 1'-oxybis[2-(2-azidoethoxy)- | Azide-PEG4-Azide | 1-AZIDO-2-(2-(2-(2-AZIDOETHOXY)ETHOXY)ETHOXY)ETHANE | A927266 | AKOS025293963 | D84626 | AS-63586 | LCZC1248 | SCHEMBL13434049 | 1-AZIDO-2-{2-[2-(2-AZIDOETHOXY

Specifications & Purity

≥95%

Storage

Store at -20°C, Argon charged

Shipped In

Ice chest + Ice pads

This product requires cold chain shipping. Ground and other economy services are not available.

Purity

≥95%

Names and Identifiers

• Canonical Smiles: C(COCCOCCOCCN=[N+]=[N-])N=[N+]=[N-]
• IUPAC Name: 1-azido-2-[2-[2-(2-azidoethoxy)ethoxy]ethoxy]ethane
• InChIKey: SFMMXKLNFMIUCH-UHFFFAOYSA-N
• INCHI: 1S/C8H16N6O3/c9-13-11-1-3-15-5-7-17-8-6-16-4-2-12-14-10/h1-8H2
• Isomeric SMILES: C(COCCOCCOCCN=[N+]=[N-])N=[N+]=[N-]
• Molecular Weight: 244.25
• Reaxy-Rn: 3548581
• Reaxys-RN_link_address: https://www.reaxys.com/reaxys/secured/hopinto.do?context=S&query=IDE.XRN=3548581&ln=

Taxonomic Classification

Taxonomy Tree

• Kingdom Organic compounds
  • Superclass Organic 1,3-dipolar compounds
    • Class Allyl-type 1,3-dipolar organic compounds
      • Subclass Azo imides

• Kingdom: Organic compounds
• Superclass: Organic 1,3-dipolar compounds
• Class: Allyl-type 1,3-dipolar organic compounds
• Subclass: Azo imides
• Intermediate Tree Nodes: Not available
• Direct Parent: Azo imides
• Alternative Parents: Azo compounds Dialkyl ethers Organic salts Hydrocarbon derivatives Organic cations
• Molecular Framework: Aliphatic acyclic compounds
• Substituents: Azo imide - Azo compound - Ether - Dialkyl ether - Organic nitrogen compound - Organic oxygen compound - Hydrocarbon derivative - Organic salt - Organooxygen compound - Organonitrogen compound - Organic cation - Aliphatic acyclic compound
• Description: This compound belongs to the class of organic compounds known as azo imides. These are n-Imides of azo compounds, analogous to azoxy compounds, having a delocalized structure.
• External Descriptors: Not available

Data sources

1. Djoumbou Feunang Y, Eisner R, Knox C, Chepelev L, Hastings J, Owen G, Fahy E, Steinbeck C, Subramanian S, Bolton E, Greiner R, and Wishart DS. ClassyFire: Automated Chemical Classification With A Comprehensive, Computable Taxonomy. Journal of Cheminformatics, 2016, 8:61.

DOI: 10.1186/s13321-016-0174-y

Chemical and Physical Properties

• Solubility: Soluble in chloroform, DCM, DMF, DMSO, or THF
• Sensitivity: Moisture sensitive
• Refractive Index: 1.47
• Boil Point(°C): 163-196 °C/760 mmHg
• Molecular Weight: 244.250 g/mol
• XLogP3: 1.600
• Hydrogen Bond Donor Count: 0
• Hydrogen Bond Acceptor Count: 7
• Rotatable Bond Count: 12
• Exact Mass: 244.128 Da
• Monoisotopic Mass: 244.128 Da
• Topological Polar Surface Area: 56.400 Ų
• Heavy Atom Count: 17
• Formal Charge: 0
• Complexity: 236.000
• Isotope Atom Count: 0
• Defined Atom Stereocenter Count: 0
• Undefined Atom Stereocenter Count: 0
• Defined Bond Stereocenter Count: 0
• Undefined Bond Stereocenter Count: 0
• The total count of all stereochemical bonds: 0
• Covalently-Bonded Unit Count: 1

References

1. Wu Feng, Chen Huan, Liu Jinyao, Pang Yan.  (2025)  Generating structurally and functionally programmable hydrogels by biological membrane hybridization.  Nature Protocols,      [PMID:40940524] [10.1038/s41596-025-01247-4]