1-Amino-4-methylpiperazine - ≥98%(GC) , CAS No.6928-85-4

CAS: 6928-85-4 Cat. No.: A151724 Molecular Weight: 115.18 Beilstein Registry Number: 23(3/4)376 EC Number: 230-053-7

GRADE & PURITY ≥98%(GC)

Synonyms

PIPERAZINE, 1-HYDRAZINYL-4-METHYL- | UNII-J5GBT1LFT2 | A836419 | CAS-6928-85-4 | EINECS 206-966-1 | DTXSID3057808 | Tox21_113841 | 1-amino 4-methylpiperazine | 1-Methyl-4-aminopierazine | A1192 | AM85350 | BCP22015 | SR-01000944741-1 | J5GBT1LFT2 | 4-(tri

Storage

Argon charged,Room temperature

Shipped In

Normal

Overview

1-Amino-4-methylpiperazine has been used:in synthesis of pyrazolo-pyrazine, -pyridine derivatives and 2-[(4-methylpiperazin-1-yl)iminomethyl]phenol;as a solvating and stabilizing agent in the preparation of uniform Ag nanoparticles (<10nm).

Specifications

Synonyms

PIPERAZINE, 1-HYDRAZINYL-4-METHYL- | UNII-J5GBT1LFT2 | A836419 | CAS-6928-85-4 | EINECS 206-966-1 | DTXSID3057808 | Tox21_113841 | 1-amino 4-methylpiperazine | 1-Methyl-4-aminopierazine | A1192 | AM85350 | BCP22015 | SR-01000944741-1 | J5GBT1LFT2 | 4-(tri

Specifications & Purity

≥98%(GC)

Storage

Argon charged, Room temperature

Shipped In

Normal

Purity

≥98%(GC)

Names and Identifiers

• Pubchem Sid: 504755521
• Pubchem Sid Url: https://pubchem.ncbi.nlm.nih.gov/substance/504755521
• Canonical Smiles: CN1CCN(CC1)N
• IUPAC Name: 4-methylpiperazin-1-amine
• InChIKey: RJWLLQWLBMJCFD-UHFFFAOYSA-N
• INCHI: 1S/C5H13N3/c1-7-2-4-8(6)5-3-7/h2-6H2,1H3
• Isomeric SMILES: CN1CCN(CC1)N
• WGK Germany: 3
• Molecular Weight: 115.18
• Beilstein: 23(3/4)376
• Reaxy-Rn: 103334
• Reaxys-RN_link_address: https://www.reaxys.com/reaxys/secured/hopinto.do?context=S&query=IDE.XRN=103334&ln=

Taxonomic Classification

Taxonomy Tree

• Kingdom Organic compounds
  • Superclass Organoheterocyclic compounds
    • Class Diazinanes
      • Subclass Piperazines
        • Level5 N-alkylpiperazines
          • Level6 N-methylpiperazines

• Kingdom: Organic compounds
• Superclass: Organoheterocyclic compounds
• Class: Diazinanes
• Subclass: Piperazines
• Intermediate Tree Nodes: N-alkylpiperazines
• Direct Parent: N-methylpiperazines
• Alternative Parents: Trialkylamines Azacyclic compounds Alkylhydrazines Organopnictogen compounds Hydrocarbon derivatives
• Molecular Framework: Aliphatic heteromonocyclic compounds
• Substituents: N-methylpiperazine - Tertiary aliphatic amine - Tertiary amine - Alkylhydrazine - Azacycle - Organic nitrogen compound - Organopnictogen compound - Hydrocarbon derivative - Organonitrogen compound - Hydrazine derivative - Amine - Aliphatic heteromonocyclic compound
• Description: This compound belongs to the class of organic compounds known as n-methylpiperazines. These are organic compounds containing a piperazine ring where the nitrogen ring atom carries a methyl group.
• External Descriptors: Not available

Data sources

1. Djoumbou Feunang Y, Eisner R, Knox C, Chepelev L, Hastings J, Owen G, Fahy E, Steinbeck C, Subramanian S, Bolton E, Greiner R, and Wishart DS. ClassyFire: Automated Chemical Classification With A Comprehensive, Computable Taxonomy. Journal of Cheminformatics, 2016, 8:61.

DOI: 10.1186/s13321-016-0174-y

Mechanisms of Action

Chemical and Physical Properties

• Solubility: water: soluble
• Sensitivity: Air & Light Sensitive
• Refractive Index: 1.485
• Flash Point(°F): 103°C
• Flash Point(°C): 103°C
• Boil Point(°C): 175°C
• Molecular Weight: 115.180 g/mol
• XLogP3: -1.100
• Hydrogen Bond Donor Count: 1
• Hydrogen Bond Acceptor Count: 3
• Rotatable Bond Count: 0
• Exact Mass: 115.111 Da
• Monoisotopic Mass: 115.111 Da
• Topological Polar Surface Area: 32.500 Ų
• Heavy Atom Count: 8
• Formal Charge: 0
• Complexity: 66.100
• Isotope Atom Count: 0
• Defined Atom Stereocenter Count: 0
• Undefined Atom Stereocenter Count: 0
• Defined Bond Stereocenter Count: 0
• Undefined Bond Stereocenter Count: 0
• The total count of all stereochemical bonds: 0
• Covalently-Bonded Unit Count: 1

References

1. Jie Liu, Youzhi Li, Kairuo Yan, Jinghua Han, Ziqi Wu, Ying Li.  (2025)  Exploring Reductive Stress as a Regulation Approach for Pseudomonas Aeruginosa Biofilm.  iScience,      [PMID:41362616] [10.1016/j.isci.2025.113973]