1-oleoyl-2-hydroxy-sn-glycero-3-phosphate (sodium salt) - ≥99% , CAS No.325465-93-8

CAS: 325465-93-8 Cat. No.: O130509 Molecular Weight: 458.502 PubChem CID: 44159357

GRADE & PURITY ≥99%

Synonyms

110681 | Sodium (R,Z)-2-hydroxy-3-(oleoyloxy)propyl hydrogenphosphate | 1-Oleoyl lysophosphatidic acid sodium salt | BML3-F05 | 18:1 Lyso PA, 1-oleoyl-2-hydroxy-sn-glycero-3-phosphate (sodium salt), powder | AS-70570 | sodium;[(2R)-2-hydroxy-3-[(Z)-octade

Storage

Store at -20°C

Shipped In

Ice chest + Ice pads

Overview

1-Oleoyl lysophosphatidic acid sodium salt is an endogenous agonist of LPA1 and LPA2, which promotes mitotic division by inducing DNA synthesis and is involved in normal and pathological emotional responses such as anxiety and depression

Specifications

Synonyms

110681 | Sodium (R, Z)-2-hydroxy-3-(oleoyloxy)propyl hydrogenphosphate | 1-Oleoyl lysophosphatidic acid sodium salt | BML3-F05 | 18:1 Lyso PA, 1-oleoyl-2-hydroxy-sn-glycero-3-phosphate (sodium salt), powder | AS-70570 | sodium;[(2R)-2-hydroxy-3-[(Z)-octade

Specifications & Purity

≥99%

Biochemical and Physiological Mechanisms

Endogenous agonist of the lysophospholipid receptors LPA1and LPA2. Inhibits differentiation of neural stem cells (NSCs) into neurons.Biological responses to LPA: Cell proliferation, inhibition of differentiation (neuroblastoma cells, myoblasts), platelet

Storage

Store at -20°C

Shipped In

Ice chest + Ice pads

This product requires cold chain shipping. Ground and other economy services are not available.

Action Type

ACTIVATOR

Purity

≥99%

Names and Identifiers

• Canonical Smiles: CCCCCCCCC=CCCCCCCCC(=O)OCC(COP(=O)(O)[O-])O.[Na+]
• IUPAC Name: sodium;[(2R)-2-hydroxy-3-[(Z)-octadec-9-enoyl]oxypropyl] hydrogen phosphate
• InChIKey: XGRLSUFHELJJAB-JGSYTFBMSA-M
• INCHI: 1S/C21H41O7P.Na/c1-2-3-4-5-6-7-8-9-10-11-12-13-14-15-16-17-21(23)27-18-20(22)19-28-29(24,25)26;/h9-10,20,22H,2-8,11-19H2,1H3,(H2,24,25,26);/q;+1/p-1/b10-9-;/t20-;/m1./s1
• Isomeric SMILES: CCCCCCCC/C=C\CCCCCCCC(=O)OC[C@H](COP(=O)(O)[O-])O.[Na+]
• PubChem CID: 44159357
• Molecular Weight: 458.502

Taxonomic Classification

Taxonomy Tree

• Kingdom Organic compounds
  • Superclass Lipids and lipid-like molecules
    • Class Glycerophospholipids
      • Subclass Glycerophosphates
        • Level5 Monoacylglycerophosphates
          • Level6 Lysophosphatidic acids
            • Level7 1-acylglycerol-3-phosphates

• Kingdom: Organic compounds
• Superclass: Lipids and lipid-like molecules
• Class: Glycerophospholipids
• Subclass: Glycerophosphates
• Intermediate Tree Nodes: Monoacylglycerophosphates - Lysophosphatidic acids
• Direct Parent: 1-acylglycerol-3-phosphates
• Alternative Parents: Fatty acid esters Alkyl phosphates Secondary alcohols Carboxylic acid esters Monocarboxylic acids and derivatives Organic sodium salts Organic oxides Hydrocarbon derivatives Carbonyl compounds Organic cations
• Molecular Framework: Aliphatic acyclic compounds
• Substituents: 1-acylglycerol-3-phosphate - Fatty acid ester - Organic phosphoric acid derivative - Phosphoric acid ester - Alkyl phosphate - Fatty acyl - Secondary alcohol - Carboxylic acid ester - Monocarboxylic acid or derivatives - Carboxylic acid derivative - Organic alkali metal salt - Organic salt - Alcohol - Organooxygen compound - Organic oxygen compound - Organic oxide - Carbonyl group - Organic sodium salt - Hydrocarbon derivative - Organic cation - Aliphatic acyclic compound
• Description: This compound belongs to the class of organic compounds known as 1-acylglycerol-3-phosphates. These are lysophosphatidic acids where the glycerol is esterified with a fatty acid at O-1 position.
• External Descriptors: Not available

Data sources

1. Djoumbou Feunang Y, Eisner R, Knox C, Chepelev L, Hastings J, Owen G, Fahy E, Steinbeck C, Subramanian S, Bolton E, Greiner R, and Wishart DS. ClassyFire: Automated Chemical Classification With A Comprehensive, Computable Taxonomy. Journal of Cheminformatics, 2016, 8:61.

DOI: 10.1186/s13321-016-0174-y

Chemical and Physical Properties

• Solubility: Soluble in chloroform, methanol, acetic acid (10 mg/mL), water (5 mg/mL, with sonication), and DMSO (0.5 mg/mL, warm).
• Molecular Weight: 458.500 g/mol
• Hydrogen Bond Donor Count: 2
• Hydrogen Bond Acceptor Count: 7
• Rotatable Bond Count: 21
• Exact Mass: 458.241 Da
• Monoisotopic Mass: 458.241 Da
• Topological Polar Surface Area: 116.000 Ų
• Heavy Atom Count: 30
• Formal Charge: 0
• Complexity: 474.000
• Isotope Atom Count: 0
• Defined Atom Stereocenter Count: 1
• Undefined Atom Stereocenter Count: 0
• Defined Bond Stereocenter Count: 1
• Undefined Bond Stereocenter Count: 0
• The total count of all stereochemical bonds: 1
• Covalently-Bonded Unit Count: 2

XLogP3