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· · COA & SDS available for every product · Same-day shipping on in-stock items (1R,2R)-ML-SI3 - ≥99% , CAS No.2418594-00-8
Storage
Protected from light,Store at -80°C
Shipped In
Dry ice packs + Cold packs
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Why this grade ≥99% for sensitive chromatographic and analytical workflows requiring minimal baseline interference.
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Storage & shipping Protected from light,Store at -80°C Ships Dry ice packs + Cold packs Check lot-specific COA for exact specifications.
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Quality documents SDS, COA, datasheet, and spec sheet available for download. Lot-specific COA accessible via lot number lookup.
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Literature proof Cited in 0 peer-reviewed publications across chromatography, organic synthesis, and cross-coupling reactions.
Overview (1R,2R)-ML-SI3 is a potent inhibitor of both TRPML1 and TRPML2 ( IC 50 values of 1.6 and 2.3 μM) and a weak inhibitor ( IC 50 12.5 μM) of TRPML3
Form:Solid
IC50& Target:TRPML1 1.6 μM (IC 50 ) TRPML2 2.3 μM (IC 50 ) TRPML3 12.5 μM (IC 50 )
Specifications Specifications & Purity
≥99%
Biochemical and Physiological Mechanisms
(1R, 2R)-ML-SI3 is a potent inhibitor of both TRPML1 and TRPML2 ( IC 50 values of 1.6 and 2.3 μM) and a weak inhibitor ( IC 50 12.5 μM) of TRPML3.
Storage
Protected from light, Store at -80°C
Shipped In
Dry ice packs + Cold packs
This product requires cold chain shipping. Ground and other economy services are not available.
Names and Identifiers Isomeric SMILES COC1=CC=CC=C1N2CCN(CC2)[C@@H]3CCCC[C@H]3NS(=O)(=O)C4=CC=CC=C4 PubChem CID 94784696 Molecular Weight 429.58
Documentation 📋 Safety Data Sheet (SDS) Comprehensive hazard, handling, storage, and regulatory compliance document.
Download SDS → ✅ Certificate of Analysis (COA) Lot-specific quality data. Enter your lot number to retrieve the exact COA.
Look up COA → 📊 Datasheet Quick-reference summary of product specifications and applications.
View datasheet → 🔬 Specification Sheet Full quality attributes and acceptance criteria for this grade.
View spec sheet →
Advanced Data Associated Targets(Human) Mechanisms of Action Certificates（CoA,COO,BSE/TSE and Analysis Chart) Chemical and Physical Properties Solubility DMSO : 50 mg/mL (116.39 mM; Need ultrasonic) Molecular Weight 429.600 g/mol XLogP3 3.800 Hydrogen Bond Donor Count 1 Hydrogen Bond Acceptor Count 6 Rotatable Bond Count 6 Exact Mass 429.209 Da Monoisotopic Mass 429.209 Da Topological Polar Surface Area 70.300 Ų Heavy Atom Count 30 Formal Charge 0 Complexity 624.000 Isotope Atom Count 0 Defined Atom Stereocenter Count 2 Undefined Atom Stereocenter Count 0 Defined Bond Stereocenter Count 0 Undefined Bond Stereocenter Count 0 The total count of all stereochemical bonds 0 Covalently-Bonded Unit Count 1
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