≥98% for sensitive chromatographic and analytical workflows requiring minimal baseline interference.
Room temperature Ships Normal Check lot-specific COA for exact specifications.
SDS, COA, datasheet, and spec sheet available for download. Lot-specific COA accessible via lot number lookup.
Cited in 1 peer-reviewed publications across chromatography, organic synthesis, and cross-coupling reactions.
application：
4-Hydroxyphthalic acid is used as a precursor to prepare 3,5-dichloro-4-hydroxyphthalic acid using the reagent aqueous acetic acid and chlorine. Further, it is also used as a starting material in the manufacture of N-(4-carboxyphenyl)-4-acetoxyphthalimide.
| Pubchem Sid | 488181462 |
|---|---|
| Pubchem Sid Url | https://pubchem.ncbi.nlm.nih.gov/substance/488181462 |
| Canonical Smiles | C1=CC(=C(C=C1O)C(=O)O)C(=O)O |
| IUPAC Name | 4-hydroxyphthalic acid |
| InChIKey | MWRVRCAFWBBXTL-UHFFFAOYSA-N |
| INCHI | 1S/C8H6O5/c9-4-1-2-5(7(10)11)6(3-4)8(12)13/h1-3,9H,(H,10,11)(H,12,13) |
| Isomeric SMILES | C1=CC(=C(C=C1O)C(=O)O)C(=O)O |
| Molecular Weight | 182.13 |
| Beilstein | 10(3)2190 |
| Reaxy-Rn | 2102555 |
| Reaxys-RN_link_address | https://www.reaxys.com/reaxys/secured/hopinto.do?context=S&query=IDE.XRN=2102555&ln= |
Comprehensive hazard, handling, storage, and regulatory compliance document.
Download SDS →Lot-specific quality data. Enter your lot number to retrieve the exact COA.
Look up COA →Full quality attributes and acceptance criteria for this grade.
View spec sheet →Taxonomy Tree
| Kingdom | Organic compounds |
|---|---|
| Superclass | Benzenoids |
| Class | Benzene and substituted derivatives |
| Subclass | Benzoic acids and derivatives |
| Intermediate Tree Nodes | Not available |
| Direct Parent | Hydroxybenzoic acid derivatives |
| Alternative Parents | Benzoic acids Benzoyl derivatives 1-hydroxy-2-unsubstituted benzenoids Dicarboxylic acids and derivatives Carboxylic acids Organooxygen compounds Organic oxides Hydrocarbon derivatives |
| Molecular Framework | Aromatic homomonocyclic compounds |
| Substituents | Hydroxybenzoic acid - Benzoic acid - Benzoyl - 1-hydroxy-2-unsubstituted benzenoid - Phenol - Dicarboxylic acid or derivatives - Carboxylic acid - Carboxylic acid derivative - Organic oxygen compound - Organic oxide - Hydrocarbon derivative - Organooxygen compound - Aromatic homomonocyclic compound |
| Description | This compound belongs to the class of organic compounds known as hydroxybenzoic acid derivatives. These are compounds containing a hydroxybenzoic acid (or a derivative), which is a benzene ring bearing a carboxyl and a hydroxyl groups. |
| External Descriptors | phenols - benzenedicarboxylic acid |
Find and download the COA for your product by matching the lot number on the packaging.
| Lot Number | Certificate Type | Date | Item |
|---|---|---|---|
 J2527084 | Certificate of Analysis | Oct 29, 2025 | H135653 |
| E2308643 | Certificate of Analysis | Feb 07, 2025 | H135653 |
| E2308647 | Certificate of Analysis | Feb 07, 2025 | H135653 |
| E2308648 | Certificate of Analysis | Feb 07, 2025 | H135653 |
| E2308654 | Certificate of Analysis | Feb 07, 2025 | H135653 |
| E2308655 | Certificate of Analysis | Feb 07, 2025 | H135653 |
| E2308659 | Certificate of Analysis | Feb 07, 2025 | H135653 |
| E2308660 | Certificate of Analysis | Feb 07, 2025 | H135653 |
| K2130418 | Certificate of Analysis | Sep 15, 2023 | H135653 |
| K2130419 | Certificate of Analysis | Sep 15, 2023 | H135653 |
| L1910001 | Certificate of Analysis | Jul 07, 2023 | H135653 |
| Solubility | Slightly miscible with water. |
|---|---|
| Melt Point(°C) | 190°C |
| Molecular Weight | 182.130 g/mol |
| XLogP3 | 1.000 |
| Hydrogen Bond Donor Count | 3 |
| Hydrogen Bond Acceptor Count | 5 |
| Rotatable Bond Count | 2 |
| Exact Mass | 182.022 Da |
| Monoisotopic Mass | 182.022 Da |
| Topological Polar Surface Area | 94.800 Ų |
| Heavy Atom Count | 13 |
| Formal Charge | 0 |
| Complexity | 225.000 |
| Isotope Atom Count | 0 |
| Defined Atom Stereocenter Count | 0 |
| Undefined Atom Stereocenter Count | 0 |
| Defined Bond Stereocenter Count | 0 |
| Undefined Bond Stereocenter Count | 0 |
| The total count of all stereochemical bonds | 0 |
| Covalently-Bonded Unit Count | 1 |
| 1. Wei-Wei Liu, Jie Pan, Xiaoyuan Feng, Meng Li, Ying Xu, Fengping Wang, Ning-Yi Zhou. (2019) Evidences of aromatic degradation dominantly via the phenylacetic acid pathway in marine benthic Thermoprofundales. ENVIRONMENTAL MICROBIOLOGY, 22 (1): (329-342). [PMID:31691434] [10.1111/1462-2920.14850] |
