5-Bromo-1H-pyrazolo[3,4-b]pyridin-3-amine - ≥97% , CAS No.405224-24-0

CAS: 405224-24-0 Cat. No.: B170187 Molecular Weight: 213.03 EC Number: 640-577-1 PubChem CID: 9834334

COA

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5-Bromo-1H-pyrazolo[3,4-b]pyridin-3-amine - ≥97% CAS No(405224-24-0) by Aladdin Scientific

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AVAILABLE TO ORDER

GRADE & PURITY ≥97%

Synonyms

5-Bromo-1H-pyrazolo[3,4-b]pyridin-3-amine, AldrichCPR | AM20061817 | FS-1012 | SC1951 | 5-Bromo-1H-pyrazolo[3,4-b]pyridin-3-ylamine | AKOS015834508 | J-516804 | AC-28893 | 5-Bromo-2H-pyrazolo[3,4-b]pyridin-3-ylamine | MFCD08059261 | A825153 | SY003018 | 5

Storage

Room temperature

Shipped In

Normal

Specifications Names and Identifiers Documentation Advanced Data Taxonomic Classification 3D Structure Associated Targets(Human) Mechanisms of Action Certificates（CoA,COO,BSE/TSE and Analysis Chart) Chemical and Physical Properties Solution Calculators Reviews

🧪

Why this grade

≥97% for sensitive chromatographic and analytical workflows requiring minimal baseline interference.

🌡

Storage & shipping

Room temperature Ships Normal Check lot-specific COA for exact specifications.

📋

Quality documents

SDS, COA, datasheet, and spec sheet available for download. Lot-specific COA accessible via lot number lookup.

📚

Literature proof

Cited in 0 peer-reviewed publications across chromatography, organic synthesis, and cross-coupling reactions.

Specifications

Synonyms

5-Bromo-1H-pyrazolo[3, 4-b]pyridin-3-amine, AldrichCPR | AM20061817 | FS-1012 | SC1951 | 5-Bromo-1H-pyrazolo[3, 4-b]pyridin-3-ylamine | AKOS015834508 | J-516804 | AC-28893 | 5-Bromo-2H-pyrazolo[3, 4-b]pyridin-3-ylamine | MFCD08059261 | A825153 | SY003018 | 5

Specifications & Purity

≥97%

Storage

Room temperature

Shipped In

Normal

Purity

≥97%

Names and Identifiers

Pubchem Sid	488196340
Pubchem Sid Url	https://pubchem.ncbi.nlm.nih.gov/substance/488196340
Canonical Smiles	C1=C(C=NC2=NNC(=C21)N)Br
IUPAC Name	5-bromo-2H-pyrazolo[3,4-b]pyridin-3-amine
InChIKey	SSNUTEUZXZIYTB-UHFFFAOYSA-N
INCHI	1S/C6H5BrN4/c7-3-1-4-5(8)10-11-6(4)9-2-3/h1-2H,(H3,8,9,10,11)
Isomeric SMILES	C1=C(C=NC2=NNC(=C21)N)Br
PubChem CID	9834334
Molecular Weight	213.03

Documentation

📋 Safety Data Sheet (SDS)

Comprehensive hazard, handling, storage, and regulatory compliance document.

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✅ Certificate of Analysis (COA)

Lot-specific quality data. Enter your lot number to retrieve the exact COA.

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📊 Datasheet

Quick-reference summary of product specifications and applications.

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🔬 Specification Sheet

Full quality attributes and acceptance criteria for this grade.

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Advanced Data

Taxonomic Classification

Taxonomy Tree

Kingdom Organic compounds
- Superclass Organoheterocyclic compounds
  - Class Pyrazolopyridines

Kingdom	Organic compounds
Superclass	Organoheterocyclic compounds
Class	Pyrazolopyridines
Subclass	Not available
Intermediate Tree Nodes	Not available
Direct Parent	Pyrazolopyridines
Alternative Parents	Pyridines and derivatives Aryl bromides Pyrazoles Heteroaromatic compounds Azacyclic compounds Primary amines Organobromides Hydrocarbon derivatives
Molecular Framework	Aromatic heteropolycyclic compounds
Substituents	Pyrazolopyridine - Aryl bromide - Aryl halide - Pyridine - Heteroaromatic compound - Azole - Pyrazole - Azacycle - Organonitrogen compound - Organobromide - Organohalogen compound - Amine - Hydrocarbon derivative - Organic nitrogen compound - Primary amine - Aromatic heteropolycyclic compound
Description	This compound belongs to the class of organic compounds known as pyrazolopyridines. These are compounds containing a pyrazolopyridine skeleton, which consists of a pyrazole fused to a pyridine. Pyrazole is 5-membered ring consisting of three carbon atoms and two adjacent nitrogen centers. Pyridine is a 6-membered ring with four carbon and one nitrogen atoms.
External Descriptors	Not available
1. Djoumbou Feunang Y, Eisner R, Knox C, Chepelev L, Hastings J, Owen G, Fahy E, Steinbeck C, Subramanian S, Bolton E, Greiner R, and Wishart DS. ClassyFire: Automated Chemical Classification With A Comprehensive, Computable Taxonomy. Journal of Cheminformatics, 2016, 8:61. DOI: 10.1186/s13321-016-0174-y

3D Structure

Associated Targets(Human)

ABL1 Tclin Tyrosine-protein kinase ABL (18331 Activities)

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PDGFRB Tclin Platelet-derived growth factor receptor beta (5195 Activities)

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IGF1R Tclin Insulin-like growth factor I receptor (8605 Activities)

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DAPK3 Tchem Death-associated protein kinase 3 (2108 Activities)

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FGFR1 Tclin Fibroblast growth factor receptor 1 (9149 Activities)

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AURKB Tchem Serine/threonine-protein kinase Aurora-B (6805 Activities)

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ROCK1 Tclin Rho-associated protein kinase 1 (4723 Activities)

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JAK3 Tclin Tyrosine-protein kinase JAK3 (8349 Activities)

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JAK2 Tclin Tyrosine-protein kinase JAK2 (12915 Activities)

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FLT1 Tclin Vascular endothelial growth factor receptor 1 (6262 Activities)

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KDR Tclin Vascular endothelial growth factor receptor 2 (20924 Activities)

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PTK2 Tclin Focal adhesion kinase 1 (4730 Activities)

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PRKAA1 Tclin AMP-activated protein kinase, alpha-1 subunit (2493 Activities)

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MST1R Tchem Macrophage-stimulating protein receptor (2327 Activities)

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MAP2K1 Tclin Dual specificity mitogen-activated protein kinase kinase 1 (4127 Activities)

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CDK9 Tchem Cyclin-dependent kinase 9 (2495 Activities)

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CSNK1A1 Tchem Casein kinase I alpha (2581 Activities)

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PRKACA Tchem cAMP-dependent protein kinase alpha-catalytic subunit (3475 Activities)

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DYRK1A Tchem Dual-specificity tyrosine-phosphorylation regulated kinase 1A (6484 Activities)

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PDGFRA Tclin Platelet-derived growth factor receptor alpha (5682 Activities)

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PRKCQ Tchem Protein kinase C theta (3319 Activities)

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RPS6KA3 Tchem Ribosomal protein S6 kinase alpha 3 (4284 Activities)

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CDK7 Tchem Cyclin-dependent kinase 7 (1512 Activities)

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CSF1R Tclin Macrophage colony stimulating factor receptor (5179 Activities)

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IKBKE Tchem Inhibitor of nuclear factor kappa B kinase epsilon subunit (3311 Activities)

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CDK5 Tchem Cyclin-dependent kinase 5 (3021 Activities)

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CHEK1 Tchem Serine/threonine-protein kinase Chk1 (6846 Activities)

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AURKA Tchem Serine/threonine-protein kinase Aurora-A (10240 Activities)

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CLK2 Tchem Dual specificity protein kinase CLK2 (3942 Activities)

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NEK2 Tchem Serine/threonine-protein kinase NEK2 (3514 Activities)

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LIMK1 Tchem LIM domain kinase 1 (2329 Activities)

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TNK2 Tclin Tyrosine kinase non-receptor protein 2 (2836 Activities)

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CAMK1D Tchem CaM kinase I delta (2141 Activities)

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CLK4 Tchem Dual specificity protein kinase CLK4 (4053 Activities)

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RET Tclin Tyrosine-protein kinase receptor RET (6732 Activities)

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PAK4 Tchem Serine/threonine-protein kinase PAK 4 (3212 Activities)

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NTRK2 Tclin Neurotrophic tyrosine kinase receptor type 2 (3279 Activities)

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ALK Tclin ALK tyrosine kinase receptor (7132 Activities)

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TYRO3 Tchem Tyrosine-protein kinase receptor TYRO3 (2906 Activities)

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MAP4K2 Tchem Mitogen-activated protein kinase kinase kinase kinase 2 (2692 Activities)

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DYRK1B Tchem Dual specificity tyrosine-phosphorylation-regulated kinase 1B (2654 Activities)

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CDK8 Tchem Cell division protein kinase 8 (1536 Activities)

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MAP4K4 Tchem Mitogen-activated protein kinase kinase kinase kinase 4 (2886 Activities)

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LTK Tclin Leukocyte tyrosine kinase receptor (1542 Activities)

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ACVR1 Tchem Activin receptor type-1 (1516 Activities)

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GRK5 Tchem G protein-coupled receptor kinase 5 (1126 Activities)

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Mechanisms of Action

Certificates（CoA,COO,BSE/TSE and Analysis Chart)

C of A & Other Certificates(BSE/TSE, COO):

Analytical Chart:

Find and download the COA for your product by matching the lot number on the packaging.

4 results found

Lot Number	Certificate Type	Date	Item
H2405129	Certificate of Analysis	May 20, 2026	B170187
H2405130	Certificate of Analysis	May 20, 2026	B170187
K1921105	Certificate of Analysis	Mar 04, 2025	B170187
C2317474	Certificate of Analysis	Apr 07, 2023	B170187

Chemical and Physical Properties

Molecular Weight	213.030 g/mol
XLogP3	1.200
Hydrogen Bond Donor Count	2
Hydrogen Bond Acceptor Count	3
Rotatable Bond Count	0
Exact Mass	211.97 Da
Monoisotopic Mass	211.97 Da
Topological Polar Surface Area	67.600 Å²
Heavy Atom Count	11
Formal Charge	0
Complexity	154.000
Isotope Atom Count	0
Defined Atom Stereocenter Count	0
Undefined Atom Stereocenter Count	0
Defined Bond Stereocenter Count	0
Undefined Bond Stereocenter Count	0
The total count of all stereochemical bonds	0
Covalently-Bonded Unit Count	1

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