≥98.5% for sensitive chromatographic and analytical workflows requiring minimal baseline interference.
Store at 2-8°C Ships Wet ice Check lot-specific COA for exact specifications.
SDS, COA, datasheet, and spec sheet available for download. Lot-specific COA accessible via lot number lookup.
Cited in 5 peer-reviewed publications across chromatography, organic synthesis, and cross-coupling reactions.
Atropine sulfate monohydrate is a broad-spectrum and competitive muscarinic acetylcholine receptor (mAChR) antagonist with anti-myopia effect.
| Pubchem Sid | 488190997 |
|---|---|
| Pubchem Sid Url | https://pubchem.ncbi.nlm.nih.gov/substance/488190997 |
| Canonical Smiles | CN1C2CCC1CC(C2)OC(=O)C(CO)C3=CC=CC=C3.CN1C2CCC1CC(C2)OC(=O)C(CO)C3=CC=CC=C3.O.OS(=O)(=O)O |
| IUPAC Name | [(1R,5S)-8-methyl-8-azabicyclo[3.2.1]octan-3-yl] 3-hydroxy-2-phenylpropanoate;sulfuric acid;hydrate |
| InChIKey | JPKKQJKQTPNWTR-BRYCGAMXSA-N |
| INCHI | 1S/2C17H23NO3.H2O4S.H2O/c2*1-18-13-7-8-14(18)10-15(9-13)21-17(20)16(11-19)12-5-3-2-4-6-12;1-5(2,3)4;/h2*2-6,13-16,19H,7-11H2,1H3;(H2,1,2,3,4);1H2/t2*13-,14+,15?,16?;; |
| Isomeric SMILES | CN1[C@@H]2CC[C@H]1CC(C2)OC(=O)C(CO)C3=CC=CC=C3.CN1[C@@H]2CC[C@H]1CC(C2)OC(=O)C(CO)C3=CC=CC=C3.O.OS(=O)(=O)O |
| WGK Germany | 2 |
| UN Number | 1544 |
| Molecular Weight | 694.83 |
| Beilstein | 6109275 |
| Reaxy-Rn | 25031488 |
| Reaxys-RN_link_address | https://www.reaxys.com/reaxys/secured/hopinto.do?context=S&query=IDE.XRN=25031488&ln= |
Comprehensive hazard, handling, storage, and regulatory compliance document.
Download SDS →Lot-specific quality data. Enter your lot number to retrieve the exact COA.
Look up COA →Full quality attributes and acceptance criteria for this grade.
View spec sheet →Taxonomy Tree
| Kingdom | Organic compounds |
|---|---|
| Superclass | Alkaloids and derivatives |
| Class | Tropane alkaloids |
| Subclass | Not available |
| Intermediate Tree Nodes | Not available |
| Direct Parent | Tropane alkaloids |
| Alternative Parents | Beta hydroxy acids and derivatives Piperidines Organic sulfuric acids N-alkylpyrrolidines Benzene and substituted derivatives Trialkylamines Carboxylic acid esters Amino acids and derivatives Monocarboxylic acids and derivatives Azacyclic compounds Primary alcohols Organopnictogen compounds Organic oxides Hydrocarbon derivatives Carbonyl compounds |
| Molecular Framework | Not available |
| Substituents | Tropane alkaloid - Beta-hydroxy acid - Sulfuric acid - Monocyclic benzene moiety - Hydroxy acid - Piperidine - N-alkylpyrrolidine - Benzenoid - Pyrrolidine - Organic sulfuric acid or derivatives - Tertiary aliphatic amine - Tertiary amine - Amino acid or derivatives - Carboxylic acid ester - Azacycle - Organoheterocyclic compound - Carboxylic acid derivative - Monocarboxylic acid or derivatives - Organic oxide - Organic oxygen compound - Organonitrogen compound - Amine - Organooxygen compound - Primary alcohol - Carbonyl group - Organic nitrogen compound - Alcohol - Organopnictogen compound - Hydrocarbon derivative - Aromatic heteropolycyclic compound |
| Description | This compound belongs to the class of organic compounds known as tropane alkaloids. These are organic compounds containing the nitrogenous bicyclic alkaloid parent N-Methyl-8-azabicyclo[3.2.1]octane. |
| External Descriptors | Not available |
Find and download the COA for your product by matching the lot number on the packaging.
| Lot Number | Certificate Type | Date | Item |
|---|---|---|---|
 C2204081 | Certificate of Analysis | Dec 12, 2025 | A109524 |
| C2204105 | Certificate of Analysis | Dec 12, 2025 | A109524 |
| I2111034 | Certificate of Analysis | Jun 09, 2025 | A109524 |
| I2111035 | Certificate of Analysis | Jun 09, 2025 | A109524 |
| I2111059 | Certificate of Analysis | Jun 09, 2025 | A109524 |
| D2326067 | Certificate of Analysis | Feb 17, 2023 | A109524 |
| D2326068 | Certificate of Analysis | Feb 17, 2023 | A109524 |
| D2326072 | Certificate of Analysis | Feb 17, 2023 | A109524 |
| D2326075 | Certificate of Analysis | Feb 17, 2023 | A109524 |
| B2325332 | Certificate of Analysis | Jan 25, 2022 | A109524 |
| B2325333 | Certificate of Analysis | Jan 25, 2022 | A109524 |
| C2204116 | Certificate of Analysis | Jan 25, 2022 | A109524 |
| B2325334 | Certificate of Analysis | Aug 02, 2021 | A109524 |
| Solubility | Soluble in water (2500 mg/ml) at 4°C, ethanol (200 mg/ml) at 4°C, Glycerol (400 mg/ml), and methanol. |
|---|---|
| Sensitivity | Light sensitive. |
| Melt Point(°C) | 187°C |
| Molecular Weight | 694.800 g/mol |
| XLogP3 | |
| Hydrogen Bond Donor Count | 5 |
| Hydrogen Bond Acceptor Count | 13 |
| Rotatable Bond Count | 10 |
| Exact Mass | 694.314 Da |
| Monoisotopic Mass | 694.314 Da |
| Topological Polar Surface Area | 184.000 Ų |
| Heavy Atom Count | 48 |
| Formal Charge | 0 |
| Complexity | 434.000 |
| Isotope Atom Count | 0 |
| Defined Atom Stereocenter Count | 4 |
| Undefined Atom Stereocenter Count | 2 |
| Defined Bond Stereocenter Count | 0 |
| Undefined Bond Stereocenter Count | 0 |
| The total count of all stereochemical bonds | 0 |
| Covalently-Bonded Unit Count | 4 |
| 1. Jian-Jun Meng, Jia-Wei Shen, Guang Li, Chang-Jie Ouyang, Jia-Xi Hu, Zi-Shuo Li, Hang Zhao, Yi-Ming Shi, Mei Zhang, Rong Liu, Ju-Tao Chen, Yu-Qian Ma, Huan Zhao, Tian Xue. (2023) Light modulates glucose metabolism by a retina-hypothalamus-brown adipose tissue axis. CELL, [PMID:36669474] [10.1016/j.cell.2022.12.024] |
| 2. Yi Xiao, Haomin Yi, Jingzhi Zhu, Suhua Chen, Guofang Wang, Yilong Liao, Yuanyuan Lei, Liyin Chen, Xingcai Zhang, Fangfu Ye. (2022) Evaluation of DNA adduct damage using G-quadruplex-based DNAzyme. Bioactive Materials, [PMID:36406255] [10.1016/j.bioactmat.2022.10.002] |
| 3. Yazhou Qin, Yuanzhao Wu, Binjie Wang, Jiye Wang, Xingsen Zong, Weixuan Yao. (2021) Controllable preparation of sea urchin-like Au NPs as a SERS substrate for highly sensitive detection of the toxic atropine. RSC Advances, 11 (32): (19813-19818). [PMID:35479250] [10.1039/D1RA03223B] |
| 4. Lisiqi Xie, Xiao Huang, Bin Su. (2017) Portable Sensor for the Detection of Choline and Its Derivatives Based on Silica Isoporous Membrane and Gellified Nanointerfaces. ACS Sensors, [PMID:28723110] [10.1021/acssensors.7b00166] |
| 5. Ying Miao, Huan Zhao, Yu-Fei Li, Yan-Ping Sun, Rui Bi, Hongli Li, Xin Fang, Zi-Shuo Li, Yu-Hua Ma, Long-Bao Lv, Kai An, Jian-Jun Meng, Yong-Gang Yao, Tian Xue. (2025) Light at night negatively affects mood in diurnal primate-like tree shrews via a visual pathway related to the perihabenular nucleus. PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA, 122 (23): (e2411280122). [PMID:40478874] [10.1073/pnas.2411280122] |
