The store will not work correctly when cookies are disabled.
JavaScript seems to be disabled in your browser. For the best experience on our site, be sure to turn on Javascript in your browser.
· · COA & SDS available for every product · Same-day shipping on in-stock items BMS 566419 - ≥98%(HPLC) , CAS No.566161-24-8
Synonyms
Acridone-Based Inhibitor, 4m | UNII-9688E11ZQ0 | N-(2-(6-(4-ethylpiperazin-1-yl)pyridin-3-yl)propan-2-yl)-2-fluoro-9-oxo-9,10-dihydroacridine-3-carboxamide | 9688E11ZQ0 | BDBM19289 | BMS-566419 | Q27271886 | n-[1-[6-(4-ethyl-1-piperazinyl)-3-pyridinyl]-1-
Shipped In
Ice chest + Ice pads
🧪
Why this grade ≥98%(HPLC) for sensitive chromatographic and analytical workflows requiring minimal baseline interference.
🌡
Storage & shipping Store at -20°C Ships Ice chest + Ice pads Check lot-specific COA for exact specifications.
📋
Quality documents SDS, COA, datasheet, and spec sheet available for download. Lot-specific COA accessible via lot number lookup.
📚
Literature proof Cited in 0 peer-reviewed publications across chromatography, organic synthesis, and cross-coupling reactions.
Specifications Synonyms
Acridone-Based Inhibitor, 4m | UNII-9688E11ZQ0 | N-(2-(6-(4-ethylpiperazin-1-yl)pyridin-3-yl)propan-2-yl)-2-fluoro-9-oxo-9, 10-dihydroacridine-3-carboxamide | 9688E11ZQ0 | BDBM19289 | BMS-566419 | Q27271886 | n-[1-[6-(4-ethyl-1-piperazinyl)-3-pyridinyl]-1-
Specifications & Purity
≥98%(HPLC)
Biochemical and Physiological Mechanisms
Potent inosine monophosphate dehydrogenase (IMPDH) inhibitor (IC50= 17 nM). Inhibits proliferation of human T-lymphoblasts and PBMCsin vitro. Reduces paw swelling in a rat adjuvant arthritis model. Orally available.
Shipped In
Ice chest + Ice pads
This product requires cold chain shipping. Ground and other economy services are not available.
Names and Identifiers Canonical Smiles CCN1CCN(CC1)C2=NC=C(C=C2)C(C)(C)NC(=O)C3=C(C=C4C(=C3)NC5=CC=CC=C5C4=O)F IUPAC Name N-[2-[6-(4-ethylpiperazin-1-yl)pyridin-3-yl]propan-2-yl]-2-fluoro-9-oxo-10H-acridine-3-carboxamide InChIKey XEVJUIZOZCFECP-UHFFFAOYSA-N INCHI 1S/C28H30FN5O2/c1-4-33-11-13-34(14-12-33)25-10-9-18(17-30-25)28(2,3)32-27(36)20-16-24-21(15-22(20)29)26(35)19-7-5-6-8-23(19)31-24/h5-10,15-17H,4,11-14H2,1-3H3,(H,31,35)(H,32,36) Isomeric SMILES CCN1CCN(CC1)C2=NC=C(C=C2)C(C)(C)NC(=O)C3=C(C=C4C(=C3)NC5=CC=CC=C5C4=O)F Molecular Weight 487.57 Reaxy-Rn 11171623 Reaxys-RN_link_address https://www.reaxys.com/reaxys/secured/hopinto.do?context=S&query=IDE.XRN=11171623&ln=
Documentation 📋 Safety Data Sheet (SDS) Comprehensive hazard, handling, storage, and regulatory compliance document.
Download SDS → ✅ Certificate of Analysis (COA) Lot-specific quality data. Enter your lot number to retrieve the exact COA.
Look up COA → 📊 Datasheet Quick-reference summary of product specifications and applications.
View datasheet → 🔬 Specification Sheet Full quality attributes and acceptance criteria for this grade.
View spec sheet →
Advanced Data Taxonomic Classification Kingdom Organic compounds Superclass Organoheterocyclic compounds Class Quinolines and derivatives Subclass Benzoquinolines Intermediate Tree Nodes Acridines Direct Parent Acridones Alternative Parents Quinoline carboxamides Fluoroquinolones N-arylpiperazines Pyridinylpiperazines Haloquinolines Hydroquinolones 2-halobenzoic acids and derivatives Hydroquinolines Dialkylarylamines N-alkylpiperazines Aminopyridines and derivatives Imidolactams Aryl fluorides Heteroaromatic compounds Vinylogous halides Vinylogous amides Amino acids and derivatives Secondary carboxylic acid amides Trialkylamines Azacyclic compounds Organofluorides Organooxygen compounds Hydrocarbon derivatives Organic oxides Molecular Framework Aromatic heteropolycyclic compounds Substituents Acridone - Quinoline-7-carboxamide - Fluoroquinolone - Pyridinylpiperazine - N-arylpiperazine - Haloquinoline - Dihydroquinolone - Dihydroquinoline - 2-halobenzoic acid or derivatives - Halobenzoic acid or derivatives - Dialkylarylamine - Aminopyridine - N-alkylpiperazine - Aryl fluoride - Aryl halide - 1,4-diazinane - Piperazine - Pyridine - Imidolactam - Benzenoid - Heteroaromatic compound - Vinylogous halide - Vinylogous amide - Amino acid or derivatives - Tertiary aliphatic amine - Tertiary amine - Secondary carboxylic acid amide - Carboxamide group - Azacycle - Carboxylic acid derivative - Amine - Hydrocarbon derivative - Organic nitrogen compound - Organohalogen compound - Organic oxygen compound - Organofluoride - Organonitrogen compound - Organooxygen compound - Organic oxide - Aromatic heteropolycyclic compound Description This compound belongs to the class of organic compounds known as acridones. These are acridines containing a ketone group attached to the C9 carbon atom of the acridine moiety. External Descriptors Not available Data sources 1. Djoumbou Feunang Y, Eisner R, Knox C, Chepelev L, Hastings J, Owen G, Fahy E, Steinbeck C, Subramanian S, Bolton E, Greiner R, and Wishart DS. ClassyFire: Automated Chemical Classification With A Comprehensive, Computable Taxonomy. Journal of Cheminformatics, 2016, 8:61.
3D Structure Associated Targets(Human) Associated Targets(non-human) Mechanisms of Action Certificates（CoA,COO,BSE/TSE and Analysis Chart) Chemical and Physical Properties Solubility Solvent:1eq. HCl, Max Conc. mg/mL: 24.38, Max Conc. mM: 50; Solvent:DMSO, Max Conc. mg/mL: 48.76, Max Conc. mM: 100 Molecular Weight 487.600 g/mol XLogP3 4.000 Hydrogen Bond Donor Count 2 Hydrogen Bond Acceptor Count 7 Rotatable Bond Count 5 Exact Mass 487.238 Da Monoisotopic Mass 487.238 Da Topological Polar Surface Area 77.600 Ų Heavy Atom Count 36 Formal Charge 0 Complexity 801.000 Isotope Atom Count 0 Defined Atom Stereocenter Count 0 Undefined Atom Stereocenter Count 0 Defined Bond Stereocenter Count 0 Undefined Bond Stereocenter Count 0 The total count of all stereochemical bonds 0 Covalently-Bonded Unit Count 1
Solution Calculators Molarity Calculator Determine the necessary mass, volume, or concentration for preparing a solution.
Dilution Calculator Determine the dilution needed to prepare a stock solution.
Reconstitution Calculator Reviews
We use cookies to ensure the website functions properly and, where permitted, to improve your experience. You can manage your preferences at any time in Settings. Learn more in our
Cookie Policy. Settings Agree All Decline
Shall we send you a message when we have discounts available?
Remind me later Allow
Thank you! Please check your email inbox to confirm.
Oops! Notifications are disabled.
Products are supplied to verified businesses, institutions, and qualified professionals for research and development use only. Not for use in humans, animals, diagnosis, or therapy.
Copyright © 2023–present Aladdin Scientific Corp. All rights reserved.
D2403119