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· · COA & SDS available for every product · Same-day shipping on in-stock items BMS 986094 - ≥98%(HPLC) , Hepatitis C virus NS5B RNA-dependent RNA polymerase inhibitor, CAS No.1234490-83-5, Hepatitis C virus NS5B RNA-dependent RNA polymerase inhibitor
Synonyms
DTXSID00154017 | AS-74509 | BMS 986094 | INX08189 | INX-08189 | 62F4AD749Y | 2,2-dimethylpropyl (2S)-2-[({[(2R,3R,4R,5R)-3,4-dihydroxy-5-(2-imino-6-methoxy-3,9-dihydro-2H-purin-9-yl)-4-methyloxolan-2-yl]methoxy}(naphthalen-1-yloxy)phosphoryl)amino]propano
Shipped In
Ice chest + Ice pads
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Why this grade ≥98%(HPLC) for sensitive chromatographic and analytical workflows requiring minimal baseline interference.
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Storage & shipping Store at -20°C Ships Ice chest + Ice pads Check lot-specific COA for exact specifications.
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Quality documents SDS, COA, datasheet, and spec sheet available for download. Lot-specific COA accessible via lot number lookup.
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Literature proof Cited in 0 peer-reviewed publications across chromatography, organic synthesis, and cross-coupling reactions.
Specifications Synonyms
DTXSID00154017 | AS-74509 | BMS 986094 | INX08189 | INX-08189 | 62F4AD749Y | 2, 2-dimethylpropyl (2S)-2-[({[(2R, 3R, 4R, 5R)-3, 4-dihydroxy-5-(2-imino-6-methoxy-3, 9-dihydro-2H-purin-9-yl)-4-methyloxolan-2-yl]methoxy}(naphthalen-1-yloxy)phosphoryl)amino]propano
Specifications & Purity
≥98%(HPLC)
Biochemical and Physiological Mechanisms
Potent hepatitis C virus (HCV) replication inhibitor (EC50= 35 nM). Is rapidly metabolized in primary human hepatocytes to 2'-C-methyl guanosine triphosphate, an inhibitor of HCV RNA-dependent RNA polymerase NS5b. Displays 10-fold reduction in potency in
Shipped In
Ice chest + Ice pads
This product requires cold chain shipping. Ground and other economy services are not available.
Mechanism of action
Hepatitis C virus NS5B RNA-dependent RNA polymerase inhibitor
Product Properties Names and Identifiers Canonical Smiles CC(C(=O)OCC(C)(C)C)NP(=O)(OCC1C(C(C(O1)N2C=NC3=C2N=C(N=C3OC)N)(C)O)O)OC4=CC=CC5=CC=CC=C54 IUPAC Name 2,2-dimethylpropyl (2S)-2-[[[(2R,3R,4R,5R)-5-(2-amino-6-methoxypurin-9-yl)-3,4-dihydroxy-4-methyloxolan-2-yl]methoxy-naphthalen-1-yloxyphosphoryl]amino]propanoate InChIKey YFXGICNMLCGLHJ-RSKRLRQZSA-N INCHI 1S/C30H39N6O9P/c1-17(26(38)42-15-29(2,3)4)35-46(40,45-20-13-9-11-18-10-7-8-12-19(18)20)43-14-21-23(37)30(5,39)27(44-21)36-16-32-22-24(36)33-28(31)34-25(22)41-6/h7-13,16-17,21,23,27,37,39H,14-15H2,1-6H3,(H,35,40)(H2,31,33,34)/t17-,21+,23+,27+,30+,46?/m0/s1 Isomeric SMILES C[C@@H](C(=O)OCC(C)(C)C)NP(=O)(OC[C@@H]1[C@H]([C@@]([C@@H](O1)N2C=NC3=C2N=C(N=C3OC)N)(C)O)O)OC4=CC=CC5=CC=CC=C54 Molecular Weight 658.65 Reaxy-Rn 51050972 Reaxys-RN_link_address https://www.reaxys.com/reaxys/secured/hopinto.do?context=S&query=IDE.XRN=51050972&ln=
Documentation 📋 Safety Data Sheet (SDS) Comprehensive hazard, handling, storage, and regulatory compliance document.
Download SDS → ✅ Certificate of Analysis (COA) Lot-specific quality data. Enter your lot number to retrieve the exact COA.
Look up COA → 📊 Datasheet Quick-reference summary of product specifications and applications.
View datasheet → 🔬 Specification Sheet Full quality attributes and acceptance criteria for this grade.
View spec sheet →
Advanced Data Taxonomic Classification Kingdom Organic compounds Superclass Organic acids and derivatives Class Carboxylic acids and derivatives Subclass Amino acids, peptides, and analogues Intermediate Tree Nodes Amino acids and derivatives - Alpha amino acids and derivatives Direct Parent Alpha amino acid esters Alternative Parents Alanine and derivatives Glycosylamines Pentoses Naphthalenes Hypoxanthines Phosphoric diester monoamides Alkyl aryl ethers Aminopyrimidines and derivatives Organic phosphoramides N-substituted imidazoles Tertiary alcohols Oxolanes Heteroaromatic compounds Secondary alcohols 1,2-diols Carboxylic acid esters Oxacyclic compounds Monocarboxylic acids and derivatives Azacyclic compounds Primary amines Organic oxides Carbonyl compounds Hydrocarbon derivatives Molecular Framework Aromatic heteropolycyclic compounds Substituents Alpha-amino acid ester - Alanine or derivatives - Glycosyl compound - N-glycosyl compound - Naphthalene - Hypoxanthine - Pentose monosaccharide - Imidazopyrimidine - Purine - Phosphoric diester monoamide - Alkyl aryl ether - Aminopyrimidine - Organic phosphoric acid derivative - Monosaccharide - Phosphoric acid ester - Organic phosphoric acid amide - Benzenoid - N-substituted imidazole - Pyrimidine - Azole - Oxolane - Heteroaromatic compound - Imidazole - Tertiary alcohol - Secondary alcohol - Carboxylic acid ester - 1,2-diol - Oxacycle - Azacycle - Ether - Organoheterocyclic compound - Monocarboxylic acid or derivatives - Organic oxygen compound - Alcohol - Carbonyl group - Organic nitrogen compound - Hydrocarbon derivative - Organic oxide - Primary amine - Organooxygen compound - Organonitrogen compound - Amine - Aromatic heteropolycyclic compound Description This compound belongs to the class of organic compounds known as alpha amino acid esters. These are ester derivatives of alpha amino acids. External Descriptors Not available Data sources 1. Djoumbou Feunang Y, Eisner R, Knox C, Chepelev L, Hastings J, Owen G, Fahy E, Steinbeck C, Subramanian S, Bolton E, Greiner R, and Wishart DS. ClassyFire: Automated Chemical Classification With A Comprehensive, Computable Taxonomy. Journal of Cheminformatics, 2016, 8:61.
3D Structure Associated Targets(Human) Associated Targets(non-human) Mechanisms of Action Certificates（CoA,COO,BSE/TSE and Analysis Chart) Chemical and Physical Properties Solubility Solvent:DMSO, Max Conc. mg/mL: 65.86, Max Conc. mM: 100; Solvent:ethanol, Max Conc. mg/mL: 65.86, Max Conc. mM: 100 Molecular Weight 658.600 g/mol XLogP3 2.800 Hydrogen Bond Donor Count 4 Hydrogen Bond Acceptor Count 14 Rotatable Bond Count 13 Exact Mass 658.252 Da Monoisotopic Mass 658.252 Da Topological Polar Surface Area 202.000 Ų Heavy Atom Count 46 Formal Charge 0 Complexity 1100.000 Isotope Atom Count 0 Defined Atom Stereocenter Count 5 Undefined Atom Stereocenter Count 1 Defined Bond Stereocenter Count 0 Undefined Bond Stereocenter Count 0 The total count of all stereochemical bonds 0 Covalently-Bonded Unit Count 1
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