GRADE & PURITY BioReagent

Synonyms

AKOS040740752 | CHOLESTYRAMINE RESIN | MS-27791 | Azane;2-methylbutane;trimethyl-[[4-(5-phenylhexan-3-yl)phenyl]methyl]azanium;chloride | Colestyramine | Cholestyramine

Storage

Store at 2-8°C,Desiccated

Shipped In

Wet ice

Specifications

Synonyms

AKOS040740752 | CHOLESTYRAMINE RESIN | MS-27791 | Azane;2-methylbutane;trimethyl-[[4-(5-phenylhexan-3-yl)phenyl]methyl]azanium;chloride | Colestyramine | Cholestyramine

Specifications & Purity

BioReagent

Biochemical and Physiological Mechanisms

Xiaobilian is a cation exchange resin. This resin can serve as a bile acid chelator. After exchanging chloride ions with bile acids in the small intestine, the chelated bile acids are excreted from the feces, causing a decrease in serum bile acid levels.

Storage

Store at 2-8°C, Desiccated

Shipped In

Wet ice

This product requires cold chain shipping. Ground and other economy services are not available.

Grade

BioReagent

Names and Identifiers

• Pubchem Sid: 504773508
• Pubchem Sid Url: https://pubchem.ncbi.nlm.nih.gov/substance/504773508
• Canonical Smiles: CCC(C)C.CCC(CC(C)C1=CC=CC=C1)C2=CC=C(C=C2)C[N+](C)(C)C.N.[Cl-]
• IUPAC Name: azane;2-methylbutane;trimethyl-[[4-(5-phenylhexan-3-yl)phenyl]methyl]azanium;chloride
• InChIKey: POJQWPZVKOFVHS-UHFFFAOYSA-M
• INCHI: 1S/C22H32N.C5H12.ClH.H3N/c1-6-20(16-18(2)21-10-8-7-9-11-21)22-14-12-19(13-15-22)17-23(3,4)5;1-4-5(2)3;;/h7-15,18,20H,6,16-17H2,1-5H3;5H,4H2,1-3H3;1H;1H3/q+1;;;/p-1
• Isomeric SMILES: CCC(C)C.CCC(CC(C)C1=CC=CC=C1)C2=CC=C(C=C2)C[N+](C)(C)C.N.[Cl-]
• PubChem CID: 137699107

Taxonomic Classification

Taxonomy Tree

• Kingdom Organic compounds
  • Superclass Lignans, neolignans and related compounds

• Kingdom: Organic compounds
• Superclass: Lignans, neolignans and related compounds
• Class: Not available
• Subclass: Not available
• Intermediate Tree Nodes: Not available
• Direct Parent: Lignans, neolignans and related compounds
• Alternative Parents: Linear 1,3-diarylpropanoids Alkyldimethylbenzylammonium chlorides Monocyclic monoterpenoids Aromatic monoterpenoids Phenylpropanes Phenylmethylamines Benzylamines Aralkylamines Tetraalkylammonium salts Organopnictogen compounds Organic chloride salts Hydrocarbon derivatives Saturated hydrocarbons
• Molecular Framework: Not available
• Substituents: Norlignan skeleton - Linear 1,3-diarylpropanoid - Alkyldimethylbenzylammonium chloride - Alkyldimethylbenzylammonium halide - Monoterpenoid - Monocyclic monoterpenoid - Aromatic monoterpenoid - P-cymene - Phenylpropane - Phenylmethylamine - Benzylamine - Aralkylamine - Benzenoid - Monocyclic benzene moiety - Tetraalkylammonium salt - Quaternary ammonium salt - Organic nitrogen compound - Organopnictogen compound - Hydrocarbon derivative - Organic chloride salt - Organic salt - Organonitrogen compound - Amine - Saturated hydrocarbon - Hydrocarbon - Aromatic homomonocyclic compound
• Description: This compound belongs to the class of organic compounds known as lignans, neolignans and related compounds. These are plant products of low molecular weight formed primarily from oxidative coupling of two p-propylphenol moieties. They can also be described as micromolecules with two phenylpropanoid units coupled together. They can be attached in various manners, like C5-C5', C8-C8'. Most known natural lignans are oxidized at C9 and C9´ and, based upon the way in which oxygen is incorporated into the skeleton and on the cyclization patterns, a wide range of lignans of very different structural types can be formed.
• External Descriptors: Not available

Data sources

1. Djoumbou Feunang Y, Eisner R, Knox C, Chepelev L, Hastings J, Owen G, Fahy E, Steinbeck C, Subramanian S, Bolton E, Greiner R, and Wishart DS. ClassyFire: Automated Chemical Classification With A Comprehensive, Computable Taxonomy. Journal of Cheminformatics, 2016, 8:61.

DOI: 10.1186/s13321-016-0174-y

Chemical and Physical Properties

• Sensitivity: Moisture sensitive
• Molecular Weight: 435.100 g/mol
• Hydrogen Bond Donor Count: 1
• Hydrogen Bond Acceptor Count: 2
• Rotatable Bond Count: 8
• Exact Mass: 434.343 Da
• Monoisotopic Mass: 434.343 Da
• Topological Polar Surface Area: 1.000 Ų
• Heavy Atom Count: 30
• Formal Charge: 0
• Complexity: 329.000
• Isotope Atom Count: 0
• Defined Atom Stereocenter Count: 0
• Undefined Atom Stereocenter Count: 2
• Defined Bond Stereocenter Count: 0
• Undefined Bond Stereocenter Count: 0
• The total count of all stereochemical bonds: 0
• Covalently-Bonded Unit Count: 4

XLogP3

References

1. Zijun Tao, Jian Zhang, Fuge Niu, Huien Zhang, Zhongfa Chen, Shanfu Wang, Yuli Zhang, Jie Li, Peng Liu.  (2024)  Polygonati rhizoma fermentation by Monascus ruber and evaluation of fermentation products in vitro.  PROCESS BIOCHEMISTRY,      [PMID:] [10.1016/j.procbio.2024.07.013]

2. Junxi Zhou, Qinglian Zhang, Jingjing Guan, Xiuyun Peng, Zebei Lu, Quan Zhou, Abdullah Al Mamun, Shuanghu Wang.  (2025)  Computational and Experimental Investigation of Antidiabetic Drugs on Tofacitinib Metabolism: Molecular Docking, in vitro, and in vivo Studies.  Drug Design Development and Therapy,      [PMID:40386187] [10.2147/DDDT.S507141]