Coenzyme A hydrate (free acid) - ≥85%(HPLC) , CAS No.85-61-0(anhydrous)

CAS: 85-61-0(anhydrous) Cat. No.: C130754 Molecular Weight: 767.53 (anhydrous basis) EC Number: 201-619-0

GRADE & PURITY ≥85%(HPLC)

Synonyms

CoA

Storage

Store at -20°C

Shipped In

Ice chest + Ice pads

Overview

General description：

Coenzyme A is structurally composed of 2-aminoethanethiol, pantothenic acid and phosphorylated adenosine phosphate.

Biochemical/Physiological Effects：

Coenzyme A is a cofactor involved in acyl group transfer. It is essential for carbohydrate, lipid and protein metabolism. Coenzyme A acts as a cofactor for vitamin B coenzymes.

Specifications

Synonyms

CoA

Specifications & Purity

≥85%(HPLC)

Biochemical and Physiological Mechanisms

Coenzyme A (CoA) is an essential metabolic cofactor synthesized from cysteine, pantothenate, and ATP. CoA plays important roles in many metabolic pathways, including the tricarboxylic acid cycle, and the synthesis and oxidation of fatty acids. One of the

Storage

Store at -20°C

Shipped In

Ice chest + Ice pads

This product requires cold chain shipping. Ground and other economy services are not available.

Purity

≥85%(HPLC)

Names and Identifiers

• Molecular Weight: 767.53 (anhydrous basis)

Associated Targets(Human)

NAA50 Tchem N-alpha-acetyltransferase 50 (0 Activities)

Discover Target: NAA50

Activity Type	Activity Value -log(M)	Mechanism of Action	Activity Reference	Publications (PubMed IDs)

References

1. Minglei Tao, Shengzhi Liu, Yaohan Li, Amin Liu, Zijian Sun, Vinesh Maharaj, Shouxin Li, Jingkui Tian, Wei Zhu.  (2023)  Comprehensive multi-omics analysis reveals the importance of CtCOSY in the energy metabolism and coumarin biosynthesis in Clematis terniflora DC.  INDUSTRIAL CROPS AND PRODUCTS,      [PMID:] [10.1016/j.indcrop.2023.116444]

2. Ruiqing Long, Ying Guo, Lianwu Xie, Shuyun Shi, Jinju Xu, Chaoying Tong, Qinlu Lin, Te Li.  (2020)  White pepper-derived ratiometric carbon dots for highly selective detection and imaging of coenzyme A.  FOOD CHEMISTRY,      [PMID:31991253] [10.1016/j.foodchem.2020.126171]

3. Yuefang Hu, Liangliang Zhang, Xuefeng Li, Rongjun Liu, Liyun Lin, Shulin Zhao.  (2017)  Green Preparation of S and N Co-Doped Carbon Dots from Water Chestnut and Onion as Well as Their Use as an Off–On Fluorescent Probe for the Quantification and Imaging of Coenzyme A.  ACS Sustainable Chemistry & Engineering,      [PMID:] [10.1021/acssuschemeng.7b00393]

4. Wu Rurong, Liao Lifu, Li Shijun, Yang Yanyan, Xiao Xilin, Nie Changming.  (2015)  Ratiometric colorimetric determination of coenzyme A using gold nanoparticles and a binuclear uranyl complex as optical probes.  MICROCHIMICA ACTA,  183  (2): (715-721).  [PMID:] [10.1007/s00604-015-1716-0]

5. Yating Li, Tong Xu, Yanqin Tu, Tong Li, Yifeng Wei, Yan Zhou.  (2024)  An aldolase-dependent phloroglucinol degradation pathway in Collinsella sp. zg1085.  APPLIED AND ENVIRONMENTAL MICROBIOLOGY,  90  (8):   [PMID:39028195] [10.1128/aem.01047-24]

6. Xu Duan, Haowen Duan, Chunxia Zhao, Leiyu Feng, Guohua Zhao, Yinguang Chen.  (2025)  Genome-Centric Metagenomics and Metaproteomics Profiled the Shared and Unique Taxa in Isomeric Fatty Acid-Differentiated Anaerobic Co-Digestion of Food Waste and Sludge.  ENVIRONMENTAL SCIENCE & TECHNOLOGY,      [PMID:39927429] [10.1021/acs.est.4c09839]

7. Qinnan Yang, Fei Kong, Ziyi Liu, Anxing Jian, Yue Wang, Yong He, Xiaoli Li, Bingquan Chu.  (2025)  Fe3+-assisted nitrogen-doped carbon dot fluorescence switch for ultrasensitive detection of acetyl-CoA in live microalgal cells.  SPECTROCHIMICA ACTA PART A-MOLECULAR AND BIOMOLECULAR SPECTROSCOPY,      [PMID:41344011] [10.1016/j.saa.2025.127281]