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· · COA & SDS available for every product · Same-day shipping on in-stock items CP-101,606 - Moligand™, ≥98%(HPLC) , Glutamate NMDA receptor; GRIN1/GRIN2B antagonist, CAS No.134234-12-1, Glutamate NMDA receptor; GRIN1/GRIN2B antagonist
GRADE & PURITY Moligand™ ? Moligand™ — Aladdin's line of ligands and bioactive small molecules. Use for receptor, pathway, and binding studies needing defined small-molecule tools. ≥98%(HPLC) Synonyms
CP 101606 | MLS006010672 | 1-[(S)-2-(S)-Hydroxy-2-(4-hydroxy-phenyl)-1-methyl-ethyl]-4-phenyl-piperidin-4-ol | BCP13195 | CP101606 | AKOS015959795 | Traxoprodil [INN] | DTXSID90158605 | TRAXOPRODIL [WHO-DD] | 134234-12-1 (free base) | Benzophenone,4'-bis(
Shipped In
Ice chest + Ice pads
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Why this grade Moligand™, ≥98%(HPLC) Moligand™ for sensitive chromatographic and analytical workflows requiring minimal baseline interference.
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Storage & shipping Store at -20°C Ships Ice chest + Ice pads Check lot-specific COA for exact specifications.
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Quality documents SDS, COA, datasheet, and spec sheet available for download. Lot-specific COA accessible via lot number lookup.
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Literature proof Cited in 0 peer-reviewed publications across chromatography, organic synthesis, and cross-coupling reactions.
Overview CP-101,606 has been used as a N-methyl-D-aspartate (NMDA) receptor antagonist to study its role in recovery of spinal cord injuries.
Specifications Synonyms
CP 101606 | MLS006010672 | 1-[(S)-2-(S)-Hydroxy-2-(4-hydroxy-phenyl)-1-methyl-ethyl]-4-phenyl-piperidin-4-ol | BCP13195 | CP101606 | AKOS015959795 | Traxoprodil [INN] | DTXSID90158605 | TRAXOPRODIL [WHO-DD] | 134234-12-1 (free base) | Benzophenone, 4'-bis(
Specifications & Purity
Moligand™, ≥98%(HPLC)
Biochemical and Physiological Mechanisms
曲索普地尔（CP-101606）是一种有效的N-甲基-D-天冬氨酸（NMDA）受体非竞争性拮抗剂，对NR2B亚单位具有选择性。在脑损伤和中风的动物模型中，它被证明具有神经保护作用。
CP-101606（曲索普地尔）在抑制谷氨酸诱导的大鼠死亡中起作用。它可能对人类缺血和神经退行性疾病有治疗作用。曲索普地尔由细胞色素P450（CYP）2D6代谢。
Shipped In
Ice chest + Ice pads
This product requires cold chain shipping. Ground and other economy services are not available.
Mechanism of action
Glutamate NMDA receptor; GRIN1/GRIN2B antagonist
Product Properties Names and Identifiers Pubchem Sid 504757876 Pubchem Sid Url https://pubchem.ncbi.nlm.nih.gov/substance/504757876 Canonical Smiles CC(C(C1=CC=C(C=C1)O)O)N2CCC(CC2)(C3=CC=CC=C3)O IUPAC Name 1-[(1S,2S)-1-hydroxy-1-(4-hydroxyphenyl)propan-2-yl]-4-phenylpiperidin-4-ol InChIKey QEMSVZNTSXPFJA-HNAYVOBHSA-N INCHI 1S/C20H25NO3/c1-15(19(23)16-7-9-18(22)10-8-16)21-13-11-20(24,12-14-21)17-5-3-2-4-6-17/h2-10,15,19,22-24H,11-14H2,1H3/t15-,19+/m0/s1 Isomeric SMILES C[C@@H]([C@H](C1=CC=C(C=C1)O)O)N2CCC(CC2)(C3=CC=CC=C3)O WGK Germany 3 Molecular Weight 327.42 Reaxy-Rn 13582904 Reaxys-RN_link_address https://www.reaxys.com/reaxys/secured/hopinto.do?context=S&query=IDE.XRN=13582904&ln=
Documentation 📋 Safety Data Sheet (SDS) Comprehensive hazard, handling, storage, and regulatory compliance document.
Download SDS → ✅ Certificate of Analysis (COA) Lot-specific quality data. Enter your lot number to retrieve the exact COA.
Look up COA → 📊 Datasheet Quick-reference summary of product specifications and applications.
View datasheet → 🔬 Specification Sheet Full quality attributes and acceptance criteria for this grade.
View spec sheet →
Advanced Data Taxonomic Classification Kingdom Organic compounds Superclass Organoheterocyclic compounds Class Piperidines Subclass Phenylpiperidines Intermediate Tree Nodes Not available Direct Parent Phenylpiperidines Alternative Parents Phenylpropanes Aralkylamines 1-hydroxy-2-unsubstituted benzenoids Tertiary alcohols Trialkylamines Secondary alcohols 1,2-aminoalcohols Azacyclic compounds Organopnictogen compounds Hydrocarbon derivatives Aromatic alcohols Molecular Framework Aromatic heteromonocyclic compounds Substituents Phenylpiperidine - Phenylpropane - 1-hydroxy-2-unsubstituted benzenoid - Phenol - Aralkylamine - Monocyclic benzene moiety - Benzenoid - Tertiary alcohol - Tertiary aliphatic amine - Tertiary amine - 1,2-aminoalcohol - Secondary alcohol - Azacycle - Aromatic alcohol - Hydrocarbon derivative - Organopnictogen compound - Organic oxygen compound - Organooxygen compound - Organonitrogen compound - Organic nitrogen compound - Amine - Alcohol - Aromatic heteromonocyclic compound Description This compound belongs to the class of organic compounds known as phenylpiperidines. These are compounds containing a phenylpiperidine skeleton, which consists of a piperidine bound to a phenyl group. External Descriptors Not available Data sources 1. Djoumbou Feunang Y, Eisner R, Knox C, Chepelev L, Hastings J, Owen G, Fahy E, Steinbeck C, Subramanian S, Bolton E, Greiner R, and Wishart DS. ClassyFire: Automated Chemical Classification With A Comprehensive, Computable Taxonomy. Journal of Cheminformatics, 2016, 8:61.
3D Structure Associated Targets(Human) Associated Targets(non-human) Mechanisms of Action Certificates（CoA,COO,BSE/TSE and Analysis Chart) Chemical and Physical Properties Solubility DMSO: ≥35 mg/mL Molecular Weight 327.400 g/mol XLogP3 2.300 Hydrogen Bond Donor Count 3 Hydrogen Bond Acceptor Count 4 Rotatable Bond Count 4 Exact Mass 327.183 Da Monoisotopic Mass 327.183 Da Topological Polar Surface Area 63.900 Ų Heavy Atom Count 24 Formal Charge 0 Complexity 380.000 Isotope Atom Count 0 Defined Atom Stereocenter Count 2 Undefined Atom Stereocenter Count 0 Defined Bond Stereocenter Count 0 Undefined Bond Stereocenter Count 0 The total count of all stereochemical bonds 0 Covalently-Bonded Unit Count 1
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