Cyclosporin A Acetate - ≥95% , CAS No.83602-41-9

CAS: 83602-41-9 Cat. No.: C357209 Molecular Weight: 1244.65 PubChem CID: 6438472

GRADE & PURITY ≥95%

Synonyms

B3-243 | Sdz-33-243 | OACsA | O-Acetyl C(9) cyclosporin A | Cyclosporine A acetate | Cyclosporin A, 6-acetate | 6-[(2S,3R,4R,6E)-3-(Acetyloxy)-4-methyl-2-(methylamino)-6-octenoic acid] Cyclosporin A | B 3-243 | [(E,1R,2R)-1-[(2S,5S,11S,14S,17S,20S,23R,26S

Storage

Store at -20°C

Shipped In

Ice chest + Ice pads

Overview

Cyclosporin A Acetate is a non-immunosuppressive analog of Cyclosporin A. However both Cyclosporin A Acetate and Cyclosporin A are able to inhibit IL-1 and PTH stimulated calcium release. NAG stimulated release by IL-1 is less effective by Cyclosporin A Acetate than Cyclosporin A.

Specifications

Synonyms

B3-243 | Sdz-33-243 | OACsA | O-Acetyl C(9) cyclosporin A | Cyclosporine A acetate | Cyclosporin A, 6-acetate | 6-[(2S, 3R, 4R, 6E)-3-(Acetyloxy)-4-methyl-2-(methylamino)-6-octenoic acid] Cyclosporin A | B 3-243 | [(E, 1R, 2R)-1-[(2S, 5S, 11S, 14S, 17S, 20S, 23R, 26S

Specifications & Purity

≥95%

Storage

Store at -20°C

Shipped In

Ice chest + Ice pads

This product requires cold chain shipping. Ground and other economy services are not available.

Purity

≥95%

Names and Identifiers

• Pubchem Sid: 504764183
• Pubchem Sid Url: https://pubchem.ncbi.nlm.nih.gov/substance/504764183
• Canonical Smiles: C/C=C/C[C@@H](C)C(OC(=O)C)C(N(C)C)C(=O)CCCCCCC(=O)[C@@H](NC(=O)[C@@H](NC)CC(C)C)C(C)C
• Isomeric SMILES: CC[C@H]1C(=O)N(CC(=O)N([C@H](C(=O)N[C@H](C(=O)N([C@H](C(=O)N[C@H](C(=O)N[C@@H](C(=O)N([C@@](C(=O)N[C@H](C(=O)N([C@H](C(=O)N([C@H](C(=O)N1)[C@@H]([C@H](C)C/C=C/C)OC(=O)C)C)C(C)C)C)CC(C)C)(C)CC(C)C)C)C)C)CC(C)C)C)C(C)C)CC(C)C)C)C
• PubChem CID: 6438472
• Molecular Weight: 1244.65

Chemical and Physical Properties

• Solubility: Soluble in Ethyl Acetate and Methanol
• Specific Rotation[α]: -215.6° (c = 0.2, Methanol)
• Melt Point(°C): 140-145° C