Diethyl maleate - 10mM in DMSO , CAS No.141-05-9

CAS: 141-05-9 Cat. No.: D421527 Molecular Weight: 172.18 Beilstein Registry Number: 1100825 EC Number: 205-451-9
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GRADE & PURITY 10mM in DMSO
Synonyms
2-Butenedioic acid (2E)-, 1,4-diethyl ester | NCGC00256390-01 | 2-Butenedioic acid(E)-,diethyl ester | DIETHYL MALEATE | D70233 | DTXCID80464 | NCGC00249057-01 | 2-Butenedioic acid, diethyl ester, (Z)- | Diethyl (2Z)-2-butenedioate # | Fumaric acid, dieth
Storage
Store at -80°C
Shipped In
Dry ice packs + Cold packs
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Size
Status
Price
Qty
1ml
D421527-1ml
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Why this grade

10mM in DMSO for sensitive chromatographic and analytical workflows requiring minimal baseline interference.

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Storage & shipping

Store at -80°C Ships Dry ice packs + Cold packs Check lot-specific COA for exact specifications.

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Quality documents

SDS, COA, datasheet, and spec sheet available for download. Lot-specific COA accessible via lot number lookup.

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Literature proof

Cited in 38 peer-reviewed publications across chromatography, organic synthesis, and cross-coupling reactions.

Overview

Diethylmaleate is a glutathione-depleting compound that has been shown to induce apoptosis. Reports indicate that Diethylmaleate inhibits NF κ B activation, activates PDAP1 (Pap1), and modifies the endoribonuclease action of 26S proteasomes. Diethylmaleate is an activator of GHS-R1α.
A glutathione-depleting compound that inhibits NF kappa B.

Specifications

Synonyms
2-Butenedioic acid (2E)-, 1, 4-diethyl ester | NCGC00256390-01 | 2-Butenedioic acid(E)-, diethyl ester | DIETHYL MALEATE | D70233 | DTXCID80464 | NCGC00249057-01 | 2-Butenedioic acid, diethyl ester, (Z)- | Diethyl (2Z)-2-butenedioate # | Fumaric acid, dieth
Specifications & Purity
10mM in DMSO
Storage
Store at -80°C
Shipped In
Dry ice packs + Cold packs
This product requires cold chain shipping. Ground and other economy services are not available.
Names and Identifiers
Canonical SmilesCCOC(=O)C=CC(=O)OCC
IUPAC Namediethyl (Z)-but-2-enedioate
InChIKeyIEPRKVQEAMIZSS-WAYWQWQTSA-N
INCHI1S/C8H12O4/c1-3-11-7(9)5-6-8(10)12-4-2/h5-6H,3-4H2,1-2H3/b6-5-
Isomeric SMILES CCOC(=O)/C=C\C(=O)OCC
WGK Germany 2
RTECS ON1225000
Molecular Weight 172.18
Beilstein 1100825
Reaxy-Rn 8138148
Reaxys-RN_link_address https://www.reaxys.com/reaxys/secured/hopinto.do?context=S&query=IDE.XRN=8138148&ln=

Documentation

📋 Safety Data Sheet (SDS)

Comprehensive hazard, handling, storage, and regulatory compliance document.

Download SDS →

✅ Certificate of Analysis (COA)

Lot-specific quality data. Enter your lot number to retrieve the exact COA.

Look up COA →

📊 Datasheet

Quick-reference summary of product specifications and applications.

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🔬 Specification Sheet

Full quality attributes and acceptance criteria for this grade.

View spec sheet →

Advanced Data

Taxonomic Classification

Taxonomy Tree

KingdomOrganic compounds
SuperclassLipids and lipid-like molecules
ClassFatty Acyls
SubclassFatty acid esters
Intermediate Tree Nodes Not available
Direct ParentFatty acid esters
Alternative Parents Dicarboxylic acids and derivatives  Enoate esters  Organic oxides  Hydrocarbon derivatives  Carbonyl compounds  
Molecular FrameworkAliphatic acyclic compounds
Substituents Fatty acid ester - Dicarboxylic acid or derivatives - Alpha,beta-unsaturated carboxylic ester - Enoate ester - Carboxylic acid ester - Carboxylic acid derivative - Organic oxygen compound - Organic oxide - Hydrocarbon derivative - Organooxygen compound - Carbonyl group - Aliphatic acyclic compound
DescriptionThis compound belongs to the class of organic compounds known as fatty acid esters. These are carboxylic ester derivatives of a fatty acid.
External Descriptors ethyl ester - maleate ester
3D Structure
Interactive Chemical Structure Model





Associated Targets(Human)
CCRF-CEM (65223 Activities)
Activity TypeRelationActivity valueUnitsAction TypeJournalPubMed IddoiAssay Aladdin ID
Associated Targets(non-human)
Aspergillus niger (16508 Activities)
Activity TypeRelationActivity valueUnitsAction TypeJournalPubMed IddoiAssay Aladdin ID
Candida albicans (78123 Activities)
Activity TypeRelationActivity valueUnitsAction TypeJournalPubMed IddoiAssay Aladdin ID
Rattus norvegicus (775804 Activities)
Activity TypeRelationActivity valueUnitsAction TypeJournalPubMed IddoiAssay Aladdin ID
Mucor mucedo (338 Activities)
Activity TypeRelationActivity valueUnitsAction TypeJournalPubMed IddoiAssay Aladdin ID
Tetranychus urticae (2600 Activities)
Activity TypeRelationActivity valueUnitsAction TypeJournalPubMed IddoiAssay Aladdin ID
Mechanisms of Action
Certificates(CoA,COO,BSE/TSE and Analysis Chart)
C of A & Other Certificates(BSE/TSE, COO):
Analytical Chart:
Chemical and Physical Properties
SensitivityMoisture sensitive
Refractive Index1.4402
Flash Point(°F)199°F
Flash Point(°C)93℃
Boil Point(°C)223°C
Melt Point(°C)-10°C
Molecular Weight172.180 g/mol
XLogP30.900
Hydrogen Bond Donor Count0
Hydrogen Bond Acceptor Count4
Rotatable Bond Count6
Exact Mass172.074 Da
Monoisotopic Mass172.074 Da
Topological Polar Surface Area52.600 Ų
Heavy Atom Count12
Formal Charge0
Complexity163.000
Isotope Atom Count0
Defined Atom Stereocenter Count0
Undefined Atom Stereocenter Count0
Defined Bond Stereocenter Count1
Undefined Bond Stereocenter Count0
The total count of all stereochemical bonds1
Covalently-Bonded Unit Count1
Citations of This Product
References
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