≥98% for sensitive chromatographic and analytical workflows requiring minimal baseline interference.
Room temperature Ships Normal Check lot-specific COA for exact specifications.
SDS, COA, datasheet, and spec sheet available for download. Lot-specific COA accessible via lot number lookup.
Cited in 3 peer-reviewed publications across chromatography, organic synthesis, and cross-coupling reactions.
Application：
DL-Histidine has been used to study the fouling behaviour of polyethersulfone ultrafiltration membranes made with different PVP (polyvinylpyrrolidone).
DL-Histidine is the mixed isomer of D- and L-histidine. DL-Histidine may be used to evaluate the efficiency of amino acid chiral ligand exchange media and systems and in running buffers for capillary electrophoresis.
| Pubchem Sid | 488179550 |
|---|---|
| Pubchem Sid Url | https://pubchem.ncbi.nlm.nih.gov/substance/488179550 |
| Canonical Smiles | C1=C(NC=N1)CC(C(=O)O)N |
| IUPAC Name | 2-amino-3-(1H-imidazol-5-yl)propanoic acid |
| InChIKey | HNDVDQJCIGZPNO-UHFFFAOYSA-N |
| INCHI | 1S/C6H9N3O2/c7-5(6(10)11)1-4-2-8-3-9-4/h2-3,5H,1,7H2,(H,8,9)(H,10,11) |
| Isomeric SMILES | C1=C(NC=N1)CC(C(=O)O)N |
| WGK Germany | 3 |
| Molecular Weight | 155.15 |
| Beilstein | 7800 |
| Reaxy-Rn | 7800 |
| Reaxys-RN_link_address | https://www.reaxys.com/reaxys/secured/hopinto.do?context=S&query=IDE.XRN=7800&ln= |
Comprehensive hazard, handling, storage, and regulatory compliance document.
Download SDS →Lot-specific quality data. Enter your lot number to retrieve the exact COA.
Look up COA →Full quality attributes and acceptance criteria for this grade.
View spec sheet →Taxonomy Tree
| Kingdom | Organic compounds |
|---|---|
| Superclass | Organic acids and derivatives |
| Class | Carboxylic acids and derivatives |
| Subclass | Amino acids, peptides, and analogues |
| Intermediate Tree Nodes | Amino acids and derivatives - Alpha amino acids and derivatives |
| Direct Parent | Histidine and derivatives |
| Alternative Parents | Alpha amino acids Imidazolyl carboxylic acids and derivatives Aralkylamines Heteroaromatic compounds Amino acids Monocarboxylic acids and derivatives Carboxylic acids Azacyclic compounds Organopnictogen compounds Organic oxides Monoalkylamines Hydrocarbon derivatives Carbonyl compounds |
| Molecular Framework | Aromatic heteromonocyclic compounds |
| Substituents | Histidine or derivatives - Alpha-amino acid - Imidazolyl carboxylic acid derivative - Aralkylamine - Azole - Imidazole - Heteroaromatic compound - Amino acid - Azacycle - Organoheterocyclic compound - Monocarboxylic acid or derivatives - Carboxylic acid - Organic nitrogen compound - Primary amine - Organooxygen compound - Organonitrogen compound - Primary aliphatic amine - Organic oxide - Organopnictogen compound - Carbonyl group - Organic oxygen compound - Amine - Hydrocarbon derivative - Aromatic heteromonocyclic compound |
| Description | This compound belongs to the class of organic compounds known as histidine and derivatives. These are compounds containing cysteine or a derivative thereof resulting from reaction of cysteine at the amino group or the carboxy group, or from the replacement of any hydrogen of glycine by a heteroatom. |
| External Descriptors | imidazoles - alpha-amino acid |
Find and download the COA for your product by matching the lot number on the packaging.
| Lot Number | Certificate Type | Date | Item |
|---|---|---|---|
 C2222079 | Certificate of Analysis | Jan 19, 2026 | H111055 |
| J2126226 | Certificate of Analysis | Aug 11, 2025 | H111055 |
| J2009164 | Certificate of Analysis | Jul 03, 2024 | H111055 |
| H1521028 | Certificate of Analysis | Jun 05, 2023 | H111055 |
| B2303649 | Certificate of Analysis | Dec 09, 2022 | H111055 |
| B2303662 | Certificate of Analysis | Dec 09, 2022 | H111055 |
| B2303665 | Certificate of Analysis | Dec 09, 2022 | H111055 |
| B2303670 | Certificate of Analysis | Dec 09, 2022 | H111055 |
| B2303671 | Certificate of Analysis | Dec 09, 2022 | H111055 |
| B2303676 | Certificate of Analysis | Dec 09, 2022 | H111055 |
| B2303678 | Certificate of Analysis | Dec 09, 2022 | H111055 |
| B2303682 | Certificate of Analysis | Dec 09, 2022 | H111055 |
| C2617071 | Certificate of Analysis | Dec 09, 2022 | H111055 |
| C2222078 | Certificate of Analysis | Feb 14, 2022 | H111055 |
| D2415432 | Certificate of Analysis | Feb 14, 2022 | H111055 |
| Solubility | 0.5 M HCl: soluble |
|---|---|
| Melt Point(°C) | 273°C |
| Molecular Weight | 155.150 g/mol |
| XLogP3 | -3.200 |
| Hydrogen Bond Donor Count | 3 |
| Hydrogen Bond Acceptor Count | 4 |
| Rotatable Bond Count | 3 |
| Exact Mass | 155.069 Da |
| Monoisotopic Mass | 155.069 Da |
| Topological Polar Surface Area | 92.000 Ų |
| Heavy Atom Count | 11 |
| Formal Charge | 0 |
| Complexity | 151.000 |
| Isotope Atom Count | 0 |
| Defined Atom Stereocenter Count | 0 |
| Undefined Atom Stereocenter Count | 1 |
| Defined Bond Stereocenter Count | 0 |
| Undefined Bond Stereocenter Count | 0 |
| The total count of all stereochemical bonds | 0 |
| Covalently-Bonded Unit Count | 1 |
| 1. Jian Zhang, Lingling Liang, Yanqing Miao, Yang Yang, Xin Bao, Chunye Liu. (2022) Open-tubular capillary electrochromatography with hydroxypropyl-β-cyclodextrin imprinted polymers: hybrid polyhedral oligomeric silsesquioxane as a coating for enantioseparation. RSC Advances, 12 (16): (9637-9644). [PMID:35424918] [10.1039/D2RA00079B] |
| 2. Qing Xiong, Jing Jin, Liqiong Lv, Zhisi Bu, Shengqiang Tong. (2018) Chiral ligand exchange countercurrent chromatography: Enantioseparation of amino acids. JOURNAL OF SEPARATION SCIENCE, 41 (6): (1479-1488). [PMID:29323783] [10.1002/jssc.201701117] |
| 3. Quanzhou Xu, Xing Fei, Xueqing Qiu, Xiaofei Wang, Tiejun Wang, Xuliang Lin, Sha Li, Yanlin Qin. (2024) Structure regulation of lignin-derived N-doped carbon-supported Ni catalyst for efficient upgrading of ethanol to higher alcohols. CHEMICAL ENGINEERING JOURNAL, [PMID:] [10.1016/j.cej.2024.151092] |
