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· · COA & SDS available for every product · Same-day shipping on in-stock items Fluorobexarotene - Moligand™, ≥97%(HPLC) , Agonist of Retinoid X receptor-α, CAS No.1190848-23-7, Agonist of Retinoid X receptor-α
GRADE & PURITY Moligand™ ? Moligand™ — Aladdin's line of ligands and bioactive small molecules. Use for receptor, pathway, and binding studies needing defined small-molecule tools. ≥97%(HPLC) Synonyms
GTPL8904 | 2-fluoro-4-(1-(3,5,5,8,8-pentamethyl-5,6,7,8-tetrahydronaphthalen-2-yl)vinyl)benzoic acid | AKOS024457960 | NSC783327 | NSC-783327 | Q27077689 | HY-108525 | F9994-0680 | DTXSID001021433 | 2-fluoro-4-[1-(3,5,5,8,8-pentamethyl-6,7-dihydronaphthal
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Why this grade Moligand™, ≥97%(HPLC) Moligand™ for sensitive chromatographic and analytical workflows requiring minimal baseline interference.
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Storage & shipping Store at 2-8°C Ships Wet ice Check lot-specific COA for exact specifications.
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Quality documents SDS, COA, datasheet, and spec sheet available for download. Lot-specific COA accessible via lot number lookup.
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Literature proof Cited in 0 peer-reviewed publications across chromatography, organic synthesis, and cross-coupling reactions.
Specifications Synonyms
GTPL8904 | 2-fluoro-4-(1-(3, 5, 5, 8, 8-pentamethyl-5, 6, 7, 8-tetrahydronaphthalen-2-yl)vinyl)benzoic acid | AKOS024457960 | NSC783327 | NSC-783327 | Q27077689 | HY-108525 | F9994-0680 | DTXSID001021433 | 2-fluoro-4-[1-(3, 5, 5, 8, 8-pentamethyl-6, 7-dihydronaphthal
Specifications & Purity
Moligand™, ≥97%(HPLC)
Biochemical and Physiological Mechanisms
RXR agonist (Ki= 12 nM; EC50= 43 nM at RXRαreceptors). Displays similar RAR agonist activity to bexarotene; exhibits an apparent RXR binding affinity 75% greater than bexarotene.
Shipped In
Wet ice
This product requires cold chain shipping. Ground and other economy services are not available.
Mechanism of action
Agonist of Retinoid X receptor-α
Names and Identifiers Canonical Smiles CC1=CC2=C(C=C1C(=C)C3=CC(=C(C=C3)C(=O)O)F)C(CCC2(C)C)(C)C IUPAC Name 2-fluoro-4-[1-(3,5,5,8,8-pentamethyl-6,7-dihydronaphthalen-2-yl)ethenyl]benzoic acid InChIKey LWKAWHRSPCHMPJ-UHFFFAOYSA-N INCHI 1S/C24H27FO2/c1-14-11-19-20(24(5,6)10-9-23(19,3)4)13-18(14)15(2)16-7-8-17(22(26)27)21(25)12-16/h7-8,11-13H,2,9-10H2,1,3-6H3,(H,26,27) Isomeric SMILES CC1=CC2=C(C=C1C(=C)C3=CC(=C(C=C3)C(=O)O)F)C(CCC2(C)C)(C)C Molecular Weight 366.47 Reaxy-Rn 19889910 Reaxys-RN_link_address https://www.reaxys.com/reaxys/secured/hopinto.do?context=S&query=IDE.XRN=19889910&ln=
Documentation 📋 Safety Data Sheet (SDS) Comprehensive hazard, handling, storage, and regulatory compliance document.
Download SDS → ✅ Certificate of Analysis (COA) Lot-specific quality data. Enter your lot number to retrieve the exact COA.
Look up COA → 📊 Datasheet Quick-reference summary of product specifications and applications.
View datasheet → 🔬 Specification Sheet Full quality attributes and acceptance criteria for this grade.
View spec sheet →
Advanced Data Taxonomic Classification Kingdom Organic compounds Superclass Lipids and lipid-like molecules Class Prenol lipids Subclass Retinoids Intermediate Tree Nodes Not available Direct Parent Retinoids Alternative Parents Sesquiterpenoids Tetralins Halobenzoic acids 2-halobenzoic acids Benzoic acids Styrenes Benzoyl derivatives 1-carboxy-2-haloaromatic compounds Fluorobenzenes Aryl fluorides Vinylogous halides Organooxygen compounds Organofluorides Organic oxides Hydrocarbon derivatives Molecular Framework Aromatic homopolycyclic compounds Substituents Bexarotene - Sesquiterpenoid - Bisabolane sesquiterpenoid - Tetralin - 2-halobenzoic acid or derivatives - Halobenzoic acid or derivatives - 2-halobenzoic acid - Halobenzoic acid - Benzoic acid or derivatives - Benzoic acid - 1-carboxy-2-haloaromatic compound - Styrene - Benzoyl - Fluorobenzene - Halobenzene - Benzenoid - Aryl halide - Monocyclic benzene moiety - Aryl fluoride - Vinylogous halide - Carboxylic acid - Carboxylic acid derivative - Organooxygen compound - Organofluoride - Organohalogen compound - Hydrocarbon derivative - Organic oxygen compound - Organic oxide - Aromatic homopolycyclic compound Description This compound belongs to the class of organic compounds known as retinoids. These are oxygenated derivatives of 3,7-dimethyl-1-(2,6,6-trimethylcyclohex-1-enyl)nona-1,3,5,7-tetraene and derivatives thereof. External Descriptors Not available Data sources 1. Djoumbou Feunang Y, Eisner R, Knox C, Chepelev L, Hastings J, Owen G, Fahy E, Steinbeck C, Subramanian S, Bolton E, Greiner R, and Wishart DS. ClassyFire: Automated Chemical Classification With A Comprehensive, Computable Taxonomy. Journal of Cheminformatics, 2016, 8:61.
3D Structure Associated Targets(Human) Associated Targets(non-human) Mechanisms of Action Certificates（CoA,COO,BSE/TSE and Analysis Chart) Chemical and Physical Properties Solubility Solvent:DMSO, Max Conc. mg/mL: 36.65, Max Conc. mM: 100; Solvent:ethanol, Max Conc. mg/mL: 9.16, Max Conc. mM: 25 Molecular Weight 366.500 g/mol XLogP3 7.700 Hydrogen Bond Donor Count 1 Hydrogen Bond Acceptor Count 3 Rotatable Bond Count 3 Exact Mass 366.2 Da Monoisotopic Mass 366.2 Da Topological Polar Surface Area 37.300 Ų Heavy Atom Count 27 Formal Charge 0 Complexity 593.000 Isotope Atom Count 0 Defined Atom Stereocenter Count 0 Undefined Atom Stereocenter Count 0 Defined Bond Stereocenter Count 0 Undefined Bond Stereocenter Count 0 The total count of all stereochemical bonds 0 Covalently-Bonded Unit Count 1
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