Garcinia lactone - Moligand™, ≥95% , CAS No.27750-13-6

CAS: 27750-13-6 Cat. No.: H648676 Molecular Weight: 190.11 EC Number: 635-780-7 PubChem CID: 9991606

GRADE & PURITY Moligand™, ≥95%

Synonyms

(+)-Garcinia acid | (-)-Hydroxycitric acid lactone | Hydroxycitric acid lactone

Storage

Store at -20°C,Desiccated

Shipped In

Ice chest + Ice pads

Overview

Garcinia lactone is an anti-obesity agent.(-)-Hydroxycitric acid lactone was a potent inhibitor of ATP citrate lyase, which catalyzes the extramitochondrial cleavage of citrate to oxaloacetate and acetyl-CoA.

Specifications

Synonyms

(+)-Garcinia acid | (-)-Hydroxycitric acid lactone | Hydroxycitric acid lactone

Specifications & Purity

Moligand™, ≥95%

Biochemical and Physiological Mechanisms

(-)-Hydroxycitric acid lactone (Garcinia lactone) is an anti-obesity agent and a popular weight loss food supplement. (-)-Hydroxycitric acid lactone is a potent inhibitor of ATP-citrate lyase . (-)-Hydroxycitric acid lactone catalyzes the extramitochondri

Storage

Store at -20°C, Desiccated

Shipped In

Ice chest + Ice pads

This product requires cold chain shipping. Ground and other economy services are not available.

Grade

Moligand™

Purity

≥95%

Names and Identifiers

• Canonical Smiles: C1C(=O)OC(C1(C(=O)O)O)C(=O)O
• IUPAC Name: (2S,3S)-3-hydroxy-5-oxooxolane-2,3-dicarboxylic acid
• InChIKey: PFHZIWAVXDSFTB-CVYQJGLWSA-N
• INCHI: 1S/C6H6O7/c7-2-1-6(12,5(10)11)3(13-2)4(8)9/h3,12H,1H2,(H,8,9)(H,10,11)/t3-,6+/m1/s1
• Isomeric SMILES: C1C(=O)O[C@@H]([C@@]1(C(=O)O)O)C(=O)O
• Alternate CAS: 27750-13-6
• PubChem CID: 9991606
• Molecular Weight: 190.11

Taxonomic Classification

Taxonomy Tree

• Kingdom Organic compounds
  • Superclass Organic acids and derivatives
    • Class Carboxylic acids and derivatives
      • Subclass Tricarboxylic acids and derivatives

• Kingdom: Organic compounds
• Superclass: Organic acids and derivatives
• Class: Carboxylic acids and derivatives
• Subclass: Tricarboxylic acids and derivatives
• Intermediate Tree Nodes: Not available
• Direct Parent: Tricarboxylic acids and derivatives
• Alternative Parents: Gamma butyrolactones Alpha hydroxy acids and derivatives Tetrahydrofurans Tertiary alcohols Carboxylic acid esters Oxacyclic compounds Carboxylic acids Organic oxides Hydrocarbon derivatives Carbonyl compounds
• Molecular Framework: Aliphatic heteromonocyclic compounds
• Substituents: Tricarboxylic acid or derivatives - Alpha-hydroxy acid - Gamma butyrolactone - Hydroxy acid - Tetrahydrofuran - Tertiary alcohol - Carboxylic acid ester - Lactone - Carboxylic acid - Oxacycle - Organoheterocyclic compound - Hydrocarbon derivative - Alcohol - Organic oxide - Carbonyl group - Organic oxygen compound - Organooxygen compound - Aliphatic heteromonocyclic compound
• Description: This compound belongs to the class of organic compounds known as tricarboxylic acids and derivatives. These are carboxylic acids containing exactly three carboxyl groups.
• External Descriptors: butan-4-olide - hydroxy carboxylic acid

Data sources

1. Djoumbou Feunang Y, Eisner R, Knox C, Chepelev L, Hastings J, Owen G, Fahy E, Steinbeck C, Subramanian S, Bolton E, Greiner R, and Wishart DS. ClassyFire: Automated Chemical Classification With A Comprehensive, Computable Taxonomy. Journal of Cheminformatics, 2016, 8:61.

DOI: 10.1186/s13321-016-0174-y

Mechanisms of Action

Chemical and Physical Properties

• Solubility: DMSO : 250 mg/mL (1315.03 mM; Need ultrasonic)
• Sensitivity: moisture sensitive
• Molecular Weight: 190.110 g/mol
• XLogP3: -1.200
• Hydrogen Bond Donor Count: 3
• Hydrogen Bond Acceptor Count: 7
• Rotatable Bond Count: 2
• Exact Mass: 190.011 Da
• Monoisotopic Mass: 190.011 Da
• Topological Polar Surface Area: 121.000 Ų
• Heavy Atom Count: 13
• Formal Charge: 0
• Complexity: 283.000
• Isotope Atom Count: 0
• Defined Atom Stereocenter Count: 2
• Undefined Atom Stereocenter Count: 0
• Defined Bond Stereocenter Count: 0
• Undefined Bond Stereocenter Count: 0
• The total count of all stereochemical bonds: 0
• Covalently-Bonded Unit Count: 1